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Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment.

Authors: ZamanFarasat, ZhaoYunhan, CelvinBettina, MehtaHemal H, WanJunxiang, ChrysisDionisios, OhlssonClaes, FadeelBengt, CohenPinchas, Sävendahl

Journal: FASEB J.

PubMed ID: 30657335

Doi: 10.1096/fj.201801741R

Products & Services: Catalog Antibodies Peptide Synthesis

In vitro analysis of synthetic peptides in blocking the entry of dengue virus.

Authors: JohnAsnet Mary, JittmittraphapAkanitt, ChattanadeeSiriporn, Alwin Prem AnandA, ShenbagarathaiR, LeaungwutiwongPorns

Journal: Virus Res.

PubMed ID: 30508603

Doi: 10.1016/j.virusres.2018.11.016

Products & Services: Peptide Synthesis

Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface

Authors: Warmack RA1, Boyer DR1, Zee CT1, Richards LS1, Sawaya MR1,2,3, Cascio D1,2,3, Gonen T2,4,5,6, Eisenberg DS1,2,3,4,5, Clarke SG7,8.

Journal: Nat Commun.

PubMed ID: 31350392

Doi: 10.1038/s41467-019-11183-z

Products & Services: Peptide Synthesis

Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension

Authors: Biancospino M1, Buel GR2, Niño CA1, Maspero E1, di Perrotolo RS1, Raimondi A3, Redlingshöfer L4, Weber J1, Brodsky FM5, Walters KJ6, Polo S7,8.

Journal: Nat Commun.

PubMed ID: 31672988

Doi: 10.1038/s41467-019-12855-6

Products & Services: Peptide Synthesis

In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

Authors: Jiang W1,2, Birtley JR3,4, Hung SC5,6, Wang W7, Chiou SH8, Macaubas C5,6, Kornum B9, Tian L10, Huang H8, Adler L5,11, Weaver G3, Lu L3, Ilstad-Minnihan A5, Somasundaram S5, Ayyangar S5, Davis MM6,8,12, Stern LJ3, Mellins ED13,14.

Journal: Nat Commun.

PubMed ID: 31748512

Doi: 10.1038/s41467-019-13234-x

Products & Services: Peptide Synthesis

Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation

Authors: Wrobel AG1, Kadlecova Z2, Kamenicky J3, Yang JC4, Herrmann T5, Kelly BT1, McCoy AJ1, Evans PR4, Martin S6, Müller S7, Sroubek F3, Neuhaus D4, Höning S8, Owen DJ1.

Journal: Dev Cell.

PubMed ID: 31430451

Doi: 10.1016/j.devcel.2019.07.017

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Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing

Authors: Blythe EE1, Gates SN2, Deshaies RJ3, Martin A4.

Journal: Structure.

PubMed ID: 31623962

Products & Services: Peptide Synthesis

Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis

Authors: Rosendale M1,2,3, Van TNN1,2,4, Grillo-Bosch D1,2, Sposini S1,2, Claverie L1,2, Gauthereau I1,2, Claverol S5, Choquet D1,2,6, Sainlos M7,8, Perrais D9,10.

Journal: Nat Commun.

PubMed ID: 31575863

Doi: 10.1038/s41467-019-12434-9

Products & Services: Peptide Synthesis

PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage

Authors: Raju S1, Verbaro DJ1, Egawa T2.

Journal: Cell Rep.

PubMed ID: 31775026

Products & Services: Peptide Synthesis

Amplified Cancer Immunotherapy of a Surface-Engineered Antigenic Microparticle Vaccine by Synergistically Modulating Tumor Microenvironment

Authors: Zhao H1,2, Zhao B1, Wu L1, Xiao H1, Ding K1, Zheng C1, Song Q1, Sun L1, Wang L1,2,3, Zhang Z1,2,3.

Journal: ACS Nano.

PubMed ID: 31689085

Products & Services: Peptide Synthesis