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Designed DNA-Encoded IL-36 Gamma Acts as a Potent Molecular Adjuvant Enhancing Zika Synthetic DNA Vaccine-Induced Immunity and Protection in a Lethal Challenge Model.

Authors: Louis L, Wise MC, Choi H, Villarreal DO, Muthumani K, Weiner DB.

Journal: Vaccines (Basel)

PubMed ID: 31121939

Doi: 10.3390/vaccines7020042

Products & Services: Peptide Synthesis

Computational insights into the interaction mechanism of transcription cofactor vestigial-like protein 4 binding to TEA domain transcription factor 4 by molecular dynamics simulation and molecular mechanics generalized Born/surface area) calculation.

Authors: Gao J, Zhang Y, Chen H, Chen Q, Feng D, Zhang L, Li C.

Journal: J Biomol Struct Dyn

PubMed ID: 30051771

Products & Services: Peptide Synthesis

Gene delivery into hepatic cells with ternary complexes of plasmid DNA, cationic liposomes and apolipoprotein E-derived peptide.

Authors: Hattori Y, Nakagawa Y, Onishi H.

Journal: Exp Ther Med

PubMed ID: 31572511

Doi: 10.3892/etm.2019.7863

Products & Services: Peptide Synthesis

Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis.

Authors: Santajit S, Seesuay W, Mahasongkram K, Sookrung N,, Ampawong S, Reamtong O, Diraphat P, Chaicumpa W, Indrawattana N.

Journal: Sci Rep

PubMed ID: 31624289

Doi: 10.1038/s41598-019-51089-w

Products & Services: Peptide Synthesis

Amyloid-β induced neuropathological actions are suppressed by Padina gymnospora (Phaeophyceae) and its active constituent α-bisabolol in Neuro2a cells and transgenic Caenorhabditis elegans Alzheimer's model.

Authors: Shanmuganathan B, Sathya S, Balasubramaniam B, Balamurugan K, Devi KP.

Journal: Nitric Oxide

PubMed ID: 31362072

Products & Services: Peptide Synthesis

APRIL Induces a Novel Subset of IgA+ Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1.

Authors: Fehres CM,, van Uden NO,, Yeremenko NG,, Fernandez L, Franco Salinas G, van Duivenvoorde LM,, Huard B, Morel J, Spits H, Hahne M, Baeten DLP,.

Journal: Front Immunol

PubMed ID: 31258536

Doi: 10.3389/fimmu.2019.01368

Products & Services: Peptide Synthesis

Stepwise autophosphorylation regulates biased agonism of the insulin receptor

Authors: Na-Oh Yunn, Mangeun Park, Jungeun Noh, Sung Ho Ryu

Journal: biorxiv

Doi: 0.1101/859868

Products & Services: Peptide Synthesis

Dendritic cells are crucial for cardiovascular remodeling and modulate neutrophil gelatinase-associated lipocalin expression upon mineralocorticoid receptor activation

Authors: Araos P, Prado C, Lozano M, Figueroa S, Espinoza A, Berger T, Mak TW, Jaisser F, Pacheco R, Michea L, , Amador CA

Journal: J Hypertens

PubMed ID: 31033725

Doi: 10.1097/HJH.0000000000002067

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Molecular Recognition of Rhodopsin Kinase GRK1 and Recoverin Is Tuned by Switching Intra- and Intermolecular Electrostatic Interactions

Authors: Abbas S, Marino V, Dell'Orco D, Koch KW

Journal: Biochemistry

PubMed ID: 31621304

Doi: 10.1021/acs.biochem.9b00846

Products & Services: Peptide Synthesis

Proteomic enzyme analysis of the marine fungus Paradendryphiella salina reveals alginate lyase as a minimal adaptation strategy for brown algae degradation

Authors: Pilgaard B, Wilkens C, Herbst FA, Vuillemin M, Rhein-Knudsen N, Meyer AS, Lange L

Journal: Sci Rep

PubMed ID: 31451726

Doi: 10.1038/s41598-019-48823-9

Products & Services: Peptide Synthesis