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Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate-Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults

Authors: Pillet S, Couillard J, Trépanier S, Poulin JF, Yassine-Diab B, Guy B, Ward BJ, Landry N.

Journal: PLoS ONE

PubMed ID: 31166987

Doi: 10.1371/journal.pone.0216533

Products & Services: Peptide Synthesis

Computational insights into the interaction mechanism of transcription cofactor vestigial-like protein 4 binding to TEA domain transcription factor 4 by molecular dynamics simulation and molecular mechanics generalized Born/surface area) calculation.

Authors: Gao J, Zhang Y, Chen H, Chen Q, Feng D, Zhang L, Li C.

Journal: J Biomol Struct Dyn

PubMed ID: 30051771

Products & Services: Peptide Synthesis

Gene delivery into hepatic cells with ternary complexes of plasmid DNA, cationic liposomes and apolipoprotein E-derived peptide.

Authors: Hattori Y, Nakagawa Y, Onishi H.

Journal: Exp Ther Med

PubMed ID: 31572511

Doi: 10.3892/etm.2019.7863

Products & Services: Peptide Synthesis

Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis.

Authors: Santajit S, Seesuay W, Mahasongkram K, Sookrung N,, Ampawong S, Reamtong O, Diraphat P, Chaicumpa W, Indrawattana N.

Journal: Sci Rep

PubMed ID: 31624289

Doi: 10.1038/s41598-019-51089-w

Products & Services: Peptide Synthesis

Amyloid-β induced neuropathological actions are suppressed by Padina gymnospora (Phaeophyceae) and its active constituent α-bisabolol in Neuro2a cells and transgenic Caenorhabditis elegans Alzheimer's model.

Authors: Shanmuganathan B, Sathya S, Balasubramaniam B, Balamurugan K, Devi KP.

Journal: Nitric Oxide

PubMed ID: 31362072

Products & Services: Peptide Synthesis

APRIL Induces a Novel Subset of IgA+ Regulatory B Cells That Suppress Inflammation via Expression of IL-10 and PD-L1.

Authors: Fehres CM,, van Uden NO,, Yeremenko NG,, Fernandez L, Franco Salinas G, van Duivenvoorde LM,, Huard B, Morel J, Spits H, Hahne M, Baeten DLP,.

Journal: Front Immunol

PubMed ID: 31258536

Doi: 10.3389/fimmu.2019.01368

Products & Services: Peptide Synthesis

Annexin A1 Bioactive Peptide Promotes Resolution of Neuroinflammation in a Rat Model of Exsanguinating Cardiac Arrest Treated by Emergency Preservation and Resuscitation.

Authors: Ma Q, Zhang Z,, Shim JK, Venkatraman TN, Lascola CD,, Quinones QJ, Mathew JP, Terrando N,, Podgoreanu MV.

Journal: Front Neurosci

PubMed ID: 31258464

Doi: 10.3389/fnins.2019.00608

Products & Services: Peptide Synthesis

MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions.

Authors: Grimes J,, Desai S, Charter NW, Lodge J, Moita Santos R, Isidro-Llobet A, Mason AM, Wu Z, Wolfe LA rd, Anantharaman L, Green A, Bridges AM, Dalmas Wilk DA, Brown AJ.

Journal: Pharmacol Res Perspect

PubMed ID: 31832205

Doi: 10.1002/prp2.547

Products & Services: Peptide Synthesis

Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease.

Authors: Kotomina T, Isakova-Sivak I, Matyushenko V, Kim KH, Lee Y, Jung YJ, Kang SM, Rudenko L.

Journal: Antiviral Res

PubMed ID: 31075351

Products & Services: Peptide Synthesis

LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System.

Authors: Dusi S, Angiari S, Pietronigro EC, Lopez N, Angelini G, Zenaro E, Della Bianca V, Tosadori G,, Paris F, Amoruso A, Carlucci T, Constantin G,, Rossi B.

Journal: Front Immunol

PubMed ID: 31681316

Doi: 10.3389/fimmu.2019.02436

Products & Services: Peptide Synthesis