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Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50

Authors: Sarah N. Zvornicanin; Ala M. Shaqra; Julia Flynn; Heidi Carias Martinez; Weiping Jia; Stephanie Moquin; Dustin Dovala; Daniel N. Bolon; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: MBio

PubMed ID: 40183562

Doi: 10.1128/mbio.04068-24

Products & Services: Peptide Synthesis

Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism

Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau

Journal: Nature Communications

PubMed ID: 39939597

Doi: 10.1038/s41467-025-56873-z

Products & Services: Peptide Synthesis

Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense

Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra

Journal: Nature Communications

PubMed ID: 39952938

Doi: 10.1038/s41467-025-56594-3

Products & Services: Peptide Synthesis

Pan-Variant SARS-CoV-2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes

Authors: Masaud Shah, Sung Ung Moon, Ji-Yon Shin, Ji-Hye Choi, Doyoon Kim, Hyun Goo Woo

Journal: Advanced Science

PubMed ID: 40014015

Doi: 10.1002/advs.202409919

Products & Services: Peptide Synthesis

Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50

Authors: Sarah N. Zvornicanin; Ala M. Shaqra; Julia Flynn; Heidi Carias Martinez; Weiping Jia; Stephanie Moquin; Dustin Dovala; Daniel N. Bolon; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: MBio

PubMed ID: 40183562

Doi: 10.1128/mbio.04068-24

Products & Services: Peptide Synthesis

Design and Binding Affinity of Antisense Peptides for Snake Venom Neutralization

Authors: Ivan Biru ; Tino eba; Marin Mari ; Mario Gabri evi ; Tin Weitner

Journal: Molecules

PubMed ID: 40005213

Doi: 10.3390/molecules30040903

Products & Services: Peptide Synthesis

Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50

Authors: Sarah N. Zvornicanin; Ala M. Shaqra; Julia Flynn; Heidi Carias Martinez; Weiping Jia; Stephanie Moquin; Dustin Dovala; Daniel N. Bolon; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: MBio

PubMed ID: 40183562

Doi: 10.1128/mbio.04068-24

Products & Services: Peptide Synthesis

The short conserved region-2 of LARP4 interacts with ribosome-associated RACK1 and promotes translation

Authors: Amitabh Ranjan, Sandy Mattijssen, Nithin Charlly, Isabel Cruz Gallardo, Leah F Pitman, Jennifer C Coleman, Maria R Conte, Richard J Maraia。

Journal: Nucleic Acids Res

PubMed ID: 39898547

Doi: 10.1093/nar/gkaf053

Products & Services: Peptide Synthesis

Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression

Authors: Emmanuel Labaronne, Didier Décimo, Lisa Bertrand, Laura Guiguettaz, Thibault J M Sohier, David Cluet, Valérie Vivet-Boudou, Ana Luiza Chaves Valadão, Clara Dahoui, Pauline François, Isabelle Hatin, Olivier Lambotte, Assia Samri, Brigitte Autran, Lucie Etienne, Caroline Goujon, Jean-Christophe Paillart, Olivier Namy, Bertha Cecilia Ramirez, Théophile Ohlmann, Arnaud Moris, Emiliano P Ricci

Journal: Nature Communications

PubMed ID: 39966383

Doi: 10.1038/s41467-025-56772-3

Products & Services: Peptide Synthesis

Enrichment of carcinoembryonic antigen by epitope molecularly imprinted polymer based on cucurbituril host-guest interaction

Authors: Yitong Xu, Ying Zhang, Huifeng Zhang, Yi He, Qiong Jia

Journal: Journal of chromatography. A

PubMed ID: 39644742

Doi: 10.1016/j.chroma.2024.465584

Products & Services: Peptide Synthesis