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Immunogenic neoantigens derived from gene fusions stimulate T cell responses.

Authors: YangWei，LeeKen-Wing，SrivastavaRaghvendra M，KuoFengshen，KrishnaChirag，ChowellDiego，MakarovVladimir，HoenDouglas，DalinMartin G，WexlerLeonard，GhosseinRonald，KatabiNora，NadeemZaineb，CohenMarc A，TianS Ken，RobineNicolas，AroraKanika，GeigerHeather，AgiusPhaedra，BouvierNancy，HubermanKety，VannessKatelynd，HavelJonathan J，SimsJennifer S，SamsteinRobert M，MandalRajarsi，TepeJustin，GanlyIan，HoAlan L，RiazNadeem，WongRichard J，ShuklaNeerav，ChanTimothy A，MorrisLuc

Journal: Nat. Med.

PubMed ID: 31011208

Doi: 10.1038/s41591-019-0434-2

Products & Services: Peptide Synthesis

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.

Authors: SliepenKwinten，HanByung Woo，BontjerIlja，MooijPetra，GarcesFernando，BehrensAnna-Janina，RantalainenKimmo，KumarSonu，SarkarAnita，BrouwerPhilip J M，HuaYuanzi，TolazziMonica，SchermerEdith，TorresJonathan L，OzorowskiGabriel，van der WoudePatricia，de la PeñaAlba Torrents，van BreemenMariëlle J，Camacho-SánchezJuan Miguel，BurgerJudith A，Medina-RamírezMax，GonzálezNuria，AlcamiJose，LaBrancheCelia，ScarlattiGabriella，van GilsMarit J，CrispinMax，MontefioriDavid C，WardAndrew B，KoopmanGerrit，MooreJohn P，ShattockRobin J，BogersWilly M，WilsonIan A，SandersRogi

Journal: Nat Commun

PubMed ID: 31142746

Doi: 10.1038/s41467-019-10262-5

Products & Services: Peptide Synthesis

Identification of angiotensin converting enzyme 2 (ACE2) up-regulating peptides from pea protein hydrolysate

Authors: Wang Liao, Hongbing Fan, Ping Liua, Jianping Wu

Journal: Journal of Functional Foods

Doi: 10.1016/j.jff.2019.05.051

Products & Services: Peptide Synthesis

Discovery of Novel Hepatitis B Virus Nucleocapsid Assembly Inhibitors.

Authors: Zhang X, Cheng J, Ma J, Hu Z, Wu S, Hwang N, Kulp J, Du Y, Guo JT, Chang J.

Journal: ACS Infect Dis

PubMed ID: 30525438

Doi: 10.1021/acsinfecdis.8b00269

Products & Services: Peptide Synthesis

Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer.

Authors: LoWinifred，ParkhurstMaria，RobbinsPaul F，TranEric，LuYong-Chen，JiaLi，GartnerJared J，PasettoAnna，DenigerDrew，MalekzadehParisa，SheltonThomas E，PrickettTodd，RaySatyajit，KivitzScott，PariaBiman C，KrileyIsaac，SchrumpDavid S，RosenbergStev

Journal: Cancer Immunol Res

PubMed ID: 30709841

Doi: 10.1158/2326-6066.CIR-18-0686

Products & Services: Peptide Synthesis

Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.

Authors: LuoLing，ZhangXiaohui，HiranoYoshio，TyagiPuneet，BarabásPéter，UeharaHironori，MiyaTadashi R，SinghNirbhai，ArcherBonnie，QaziYureeda，JackmanKyle，DasSubrata K，OlsenThomas，ChennamaneniSrinivas R，StaggBrian C，AhmedFaisal，EmersonLyska，ZygmuntKristen，WhitakerRoss，MamalisChristina，HuangWei，GaoGuangping，SrinivasSangly P，KrizajDavid，BaffiJudit，AmbatiJayakrishna，KompellaUday B，AmbatiBalamura

Journal: ACS Nano

PubMed ID: 23464925

Doi: 10.1021/nn305958y

Products & Services: Peptide Synthesis

FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates.

Authors: TurcoEleonora，WittMarie，AbertChristine，Bock-BierbaumTobias，SuMing-Yuan，TrapannoneRiccardo，SztachoMartin，DanieliAlberto，ShiXiaoshan，ZaffagniniGabriele，GamperAnnamaria，SchuschnigMartina，FracchiollaDorotea，BernklauDaniel，RomanovJulia，HartlMarkus，HurleyJames H，DaumkeOliver，MartensSa

Journal: Mol. Cell

PubMed ID: 30853400

Doi: 10.1016/j.molcel.2019.01.035

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Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity.

Authors: MacQuoc D，MathewsDave V，KahlaJustin A，StoffersClaire M，DelmasOlivia M，HoltBrandon Alexander，AdamsAndrew B，KwongGabri

Journal: Nat Biomed Eng

PubMed ID: 30952979

Doi: 10.1038/s41551-019-0358-7

Products & Services: Peptide Synthesis

Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist.

Authors: KohKwi Hye, CaoYanxia, MangosSteve, TardiNicholas J, DandeRanadheer R, LeeHa Won, SamelkoBeata, AltintasMehmet M, SchmitzVincent P, LeeHyun, MukherjeeKamalika, PeevVasil, CimbalukDavid J, ReiserJochen, HahmEu

Journal: J. Clin. Invest.

PubMed ID: 30747722

Doi: 10.1172/JCI123386

Products & Services: Peptide Synthesis

High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity

Authors: Fakhouri, A. S., Weist, J. L., Tomusko, A. R., & Leight, J. L.

Journal: ASSAY and Drug Development Technologies

PubMed ID: 30958702

Doi: 10.1089/adt.2018.877

Products & Services: Peptide Synthesis