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Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.

Authors: Perez-RuizElisabeth，MinuteLuna，OtanoItziar，AlvarezMaite，OchoaMaria Carmen，BelsueVirginia，de AndreaCarlos，Rodriguez-RuizMaria Esperanza，Perez-GraciaJose Luis，Marquez-RodasIvan，LlacerCasilda，AlvarezMartina，de LuqueVanesa，MolinaCarmen，TeijeiraAlvaro，BerraondoPedro，MeleroIgn

Journal: Nature

PubMed ID: 31043740

Doi: 10.1038/s41586-019-1162-y

Products & Services: Peptide Synthesis

MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.

Authors: MeixiongJames，VasavdaChirag，SnyderSolomon H，DongXinz

Journal: Proc. Natl. Acad. Sci. U.S.A.

PubMed ID: 31068464

Doi: 10.1073/pnas.1903316116

Products & Services: Peptide Synthesis

Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8 T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness.

Authors: WuJingxia，MaSicong，SandhoffRoger，MingYanan，Hotz-WagenblattAgnes，TimmermanVincent，Bonello-PalotNathalie，Schlotter-WeigelBeate，Auer-GrumbachMichaela，SeemanPavel，L?scherWolfgang N，ReindlMarkus，WeissFlorian，MahEric，WeisshaarNina，MadiAlaa，MohrKerstin，SchlimbachTilo，Velasco CárdenasRubí M-H，KoeppelJonas，Grünschl?gerFlorian，MüllerLisann，BaumeisterMaren，BrüggerBritta，SchmittMichael，WabnitzGuido，SamstagYvonne，CuiGuol

Journal: Immunity

PubMed ID: 30952607

Doi: 10.1016/j.immuni.2019.03.005

Products & Services: Peptide Synthesis

Arabidopsis ENDOMEMBRANE PROTEIN 12 contributes to the endoplasmic reticulum stress response by regulating K/HDEL receptor trafficking.

Authors: LeungKing Pong，LuoMing，GaoCaiji，ZengYonglun，ZhaoQiong，ChyeMee-Len，YaoXiaoqiang，JiangL

Journal: Plant Cell

PubMed ID: 31123049

Doi: 10.1105/tpc.18.00913

Products & Services: Peptide Synthesis

Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation.

Authors: SongYijun，CygnarKatherine D，SagdullaevBotir，ValleyMatthew，HirshSarah，StephanAaron，ReisertJohannes，ZhaoHai

Journal: Neuron

PubMed ID: 18466748

Doi: 10.1016/j.neuron.2008.02.029

Products & Services: Peptide Synthesis

Design， synthesis and biological evaluation of N-phenylthieno[2，3-d]pyrimidin-4-amines as inhibitors of FGFR1.

Authors: GryshchenkoA A，BdzholaV G，BalandaA O，BriukhovetskaN V，KoteyI M，GolubA G，RubanT P，LukashL L，Yarmolu

Journal: Bioorg. Med. Chem.

PubMed ID: 25817240

Doi: 10.1016/j.bmc.2014.12.044

Products & Services: Peptide Synthesis

Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor.

Authors: MamonovaTatyana，ZhangQiangmin，ChandraMintu，CollinsBrett M，SarfoEdward，BuZimei，XiaoKunhong，BiselloAlessandro，FriedmanPet

Journal: Biochemistry

PubMed ID: 28376304

Doi: 10.1021/acs.biochem.7b00078

Products & Services: Peptide Synthesis

Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins

Authors: Fan H, Wang J, Liao W, Jiang X, Wu J

Journal: J Agric Food Chem

PubMed ID: 31140270

Doi: 10.1021/acs.jafc.9b01071

Products & Services: Peptide Synthesis

Mechanism of CK2.3， a Novel Mimetic Peptide of Bone Morphogenetic Protein Receptor Type IA， Mediated Osteogenesis.

Authors: VrathashaVrathasha，WeidnerHilary，Nohe

Journal: Int J Mol Sci

PubMed ID: 31117181

Doi: 10.3390/ijms20102500

Products & Services: Peptide Synthesis

Molecular Recognition of Structures Is Key in the Polymerization of Patterned Barnacle Adhesive Sequences.

Authors: SoChristopher R，YatesElizabeth A，EstrellaLuis A，FearsKenan P，SchenckAshley M，YipCatherine M，WahlKathr

Journal: ACS Nano

PubMed ID: 30986028

Doi: 10.1021/acsnano.8b09194

Products & Services: Peptide Synthesis