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5′-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response

Authors: Hanyong Jin , Ji-Hyun Yeom , Eunkyoung Shin , Yoonjie Ha , Haifeng Liu , Daeyoung Kim , Minju Joo , Yong-Hak Kim , Hak Kyun Kim , Minkyung Ryu, Hong-Man Kim , Jeongkyu Kim , Keun P Kim , Yoonsoo Hahn , Jeehyeon Bae , Kangseok Lee

Journal: Nature Communications

PubMed ID: 39468069

Doi: 10.1038/s41467-024-53624-4

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Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression

Authors: Haley E Adcox , Jason R Hunt , Paige E Allen , Thomas E Siff , Kyle G Rodino , Andrew K Ottens , Jason A Carlyon

Journal: Nature Communications

PubMed ID: 39277599

Doi: 10.1038/s41467-024-52119-6

Products & Services: Custom Vector Construction Codon Optimization

Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes

Authors: Yani Arhab , Tatyana V Pestova , Christopher U T Hellen

Journal: Viruses

PubMed ID: 39339889

Doi: 10.3390/v16091413

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Efficient Chemical Synthesis of Multi-Monoubiquitylated and Diubiquitylated Histones by the α-Halogen Ketone-Mediated Strategy

Authors: Shuai Peng, Xin Liu, Chengpiao Lu, Haibo Wang, Xiaotong Liu, Qingyue Gong, Huizhong Tao, Hongrui Xu, Changlin Tian, Guoqiang Xu, Jia-Bin Li

Journal: Bioconjugate Chemistry

PubMed ID: 38954775

Doi: 10.1021/acs.bioconjchem.4c00130

Products & Services: Gene Synthesis Codon Optimization Custom Vector Construction

Andrographolide influences IDD cell autophagy and oxidative stress under mechanical pressure via miR-9/FoxO3/PINK1/Parkin molecular axis

Authors: Jianwei Liu, Dixing Lin, Jiadong Lu

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 38836662

Doi: 10.14715/cmb/2024.70.6.29

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One-shot design elevates functional expression levels of a voltage-gated potassium channel

Authors: Jonathan Jacob Weinstein, Chandamita Saikia, Izhar Karbat, Adi Goldenzweig, Eitan Reuveny, Sarel Jacob Fleishman

Journal: Protein Sci

PubMed ID: 38747377

Doi: 10.1002/pro.4995

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Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design

Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly

Journal: Structure

PubMed ID: 38870939

Doi: 10.1016/j.str.2024.05.011

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Evaluating the antibody response elicited by diverse HIV envelope immunogens in the African green monkey (Vervet) model

Authors: Thandeka Moyo-Gwete, Frances Ayres, Nonkululeko B Mzindle, Zanele Makhado, Nelia P Manamela, Simone I Richardson, Dale Kitchin, Strauss van Graan, Joritha van Heerden, Nishal Parbhoo, Gerald K Chege, Penny L Moore

Journal: Sci Rep

PubMed ID: 38858452

Doi: 10.1038/s41598-024-63703-7

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Molecular Mechanism of WWOX Inhibiting the Development of Esophageal Cancer by Inhibiting Hippo Signaling Pathway

Authors: Zihan Chen, Jingyu Sun, Lili Zhang, Yanglin Sun, Qingqing Ni, Hongkun Zhu, Miao Hui, Longzhen Zhang, Qiang Wang

Journal: Biochem Genet

PubMed ID: 38902482

Doi: 10.1007/s10528-024-10856-9

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Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage

Authors: Sarah Stuart, Daniel Tarade, Michael Ohh

Journal: Sci Rep

PubMed ID: 38926538

Doi: 10.1038/s41598-024-65537-9

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