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页码: 71/195 每页显示数量

Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells

Authors: Wolfstetter G, Pfeifer K, Backman M, Masudi TA, Mendoza-García P, Chen S, Sonnenberg H, Sukumar SK, Uçkun E, Varshney GK, Uv A, Palmer RH

Journal: Scientific REPORTS

PubMed ID: 32917927

Doi: 10.1038/s41598-020-70890-6

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PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia

Authors: Gawel JM, Shouksmith AE, Raouf YS, Nawar N, Toutah K, Bukhari S, Manaswiyoungkul P, Olaoye OO, Israelian J, Radu TB, Cabral AD, Sina D, Sedighi A, de Araujo ED, Gunning PT

Journal: European Journal of Medicinal Chemistry

PubMed ID: 32615502

Doi: 10.1016/j.ejmech.2020.112411

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Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico

Authors: Broom A, Rakotoharisoa RV, Thompson MC, Zarifi N, Nguyen E, Mukhametzhanov N, Liu L, Fraser JS, Chica RA

Journal: Nature Communications

PubMed ID: 32968058

Doi: 10.1038/s41467-020-18619-x

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A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations

Authors: Grzelak L, Temmam S, Planchais C, Demeret C, Tondeur L, Huon C, Guivel-Benhassine F, Staropoli I, Chazal M, Dufloo J, Planas D, Buchrieser J, Rajah MM, Robinot R, Porrot F, Albert M, Chen KY, Crescenzo-Chaigne B, Donati F, Anna F, Souque P, Gransagne M, Bellalou J, Nowakowski M, Backovic M, Bouadma L, Le Fevre L, Le Hingrat Q, Descamps D, Pourbaix A, Laouénan C, Ghosn J, Yazdanpanah Y, Besombes C, Jolly N, Pellerin-Fernandes S, Cheny O, Ungeheuer MN, Mellon G, Morel P, Rolland S, Rey FA, Behillil S, Enouf V, Lemaitre A, Créach MA, Petres S, Escriou N, Charneau P, Fontanet A, Hoen B, Bruel T, Eloit M, Mouquet H, Schwartz O, van der Werf S

Journal: Science Translational Medicine

PubMed ID: 32817357

Doi: 10.1126/scitranslmed.abc3103

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Quantitating denaturation by formic acid: imperfect repeats are essential to the stability of the functional amyloid protein FapC.

Authors: Christensen LFB,Nowak JS,Sønderby TV,Frank SA,Otzen DE

Journal: The Journal of Biological Chemistry

PubMed ID: 32719003

Doi: 10.1074/jbc.RA120.013396

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Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes

Authors: Cai EP, Ishikawa Y, Zhang W, Leite NC, Li J, Hou S, Kiaf B, Hollister-Lock J, Yilmaz NK, Schiffer CA, Melton DA, Kissler S, Yi P

Journal: Nature metabolism

PubMed ID: 32719542

Doi: 10.1038/s42255-020-0254-1

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Geographical distribution and molecular insights into abamectin and milbemectin cross-resistance in European field populations of Tetranychus urticae

Authors: Xue W, Snoeck S, Njiru C, Inak E, Dermauw W, Van Leeuwen T

Journal: Pest management science

PubMed ID: 32237053

Doi: 10.1002/ps.5831

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GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

Authors: Hattori SI, Higshi-Kuwata N, Raghavaiah J, Das D, Bulut H, Davis DA, Takamatsu Y, Matsuda K, Takamune N, Kishimoto N, Okamura T, Misumi S, Yarchoan R, Maeda K, Ghosh AK, Mitsuya H

Journal: MBio

PubMed ID: 32820005

Doi: 10.1128/mBio.01833-20

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The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor

Authors: Hochstoeger T, Al Said T, Maestre D, Walter F, Vilceanu A, Pedron M, Cushion TD, Snider W, Nimpf S, Nordmann GC, Landler L, Edelman N, Kruppa L, Dürnberger G, Mechtler K, Schuechner S, Ogris E, Malkemper EP, Weber S, Schleicher E, Keays DA

Journal: SCIENCE ADVANCES

PubMed ID: 32851187

Doi: 10.1126/sciadv.abb9110

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Unregulated Sphingolipid Biosynthesis in Gene-Edited Arabidopsis ORM Mutants Results in Nonviable Seeds with Strongly Reduced Oil Content

Authors: Gonzalez-Solis A, Han G, Gan L, Li Y, Markham JE, Cahoon RE, Dunn TM, Cahoon EB

Journal: The Plant cell

PubMed ID: 32527862

Doi: 10.1105/tpc.20.00015

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