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页码: 65/195 每页显示数量

The Arabidopsis active demethylase ROS1 -regulates defence genes by erasing DNA methylation at promoter-regulatory regions

Authors: Thierry Halter, Jingyu Wang, Delase Amesefe, Emmanuelle Lastrucci, Magali Charvin, Meenu Singla Rastogi, Lionel Navarro

Journal: Elife

PubMed ID: 33470193

Doi: 10.7554/eLife.62994

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Dengue virus strain 2 capsid protein switches the annealing pathway and reduces intrinsic dynamics of the conserved 5' untranslated region

Authors: Xin Ee Yong, Palur Venkata Raghuvamsi, Ganesh S Anand, Thorsten Wohland, Kamal K Sharma

Journal: RNA Biol

PubMed ID: 33406991

Doi: 10.1080/15476286.2020.1860581

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A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

Authors: Shin-Ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut, Debananda Das, Brandon J Anson, Emma K Lendy, Yuki Takamatsu, Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David A Davis, Eiichi N Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew D Mesecar, Arun K Ghosh, Hiroaki Mitsuya

Journal: Nat Commun

PubMed ID: 33510133

Doi: 10.1038/s41467-021-20900-6

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TIMELESS inhibits breast cancer cell invasion and metastasis by down-regulating the expression of MMP9

Authors: Bowen Li, Liying Mu, Yanan Li, Kangkai Xia, Yuxi Yang, Sattout Aman, Bashir Ahmad, Shujing Li, Huijian Wu

Journal: Cancer Cell Int

PubMed ID: 33430865

Doi: 10.1186/s12935-021-01752-y

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Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer

Authors: Johnathan D Guest, Ruixue Wang, Khadija H Elkholy, Andrezza Chagas, Kinlin L Chao, Thomas E Cleveland, Young Chang Kim, Zhen-Yong Keck, Alexander Marin, Abdul S Yunus, Roy A Mariuzza, Alexander K Andrianov, Eric A Toth, Steven K H Foung, Brian G Pierce, Thomas R Fuerst

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33431677

Doi: 10.1073/pnas.2015149118

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Facile Fabrication of Protein-Macrocycle Frameworks

Authors: Kiefer O Ramberg, Sylvain Engilberge, Tomasz Skorek, Peter B Crowley

Journal: J Am Chem Soc

PubMed ID: 33470808

Doi: 10.1021/jacs.0c10697

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Effects of H3 3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells

Authors: Huang TY,Piunti A,Qi J,Morgan M,Bartom E,Shilatifard A,Saratsis AM

Journal: Acta neuropathologica communications

PubMed ID: 33287886

Doi: 10.1186/s40478-020-01092-4

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Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

Authors: Cardozo KHM, Lebkuchen A, Okai GG, Schuch RA, Viana LG, Olive AN, Lazari CDS, Fraga AM, Granato CFH, Pintão MCT, Carvalho VM

Journal: Nature Communications

PubMed ID: 33273458

Doi: 10.1038/s41467-020-19925-0

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An anchoring molecule increases intravitreal retention of antibody-based therapeutics used in the treatment of ocular diseases

Authors: Gao Q, Schachar IH

Journal: Journal of controlled release : official journal of the Controlled Release Society

PubMed ID: 32858075

Doi: 10.1016/j.jconrel.2020.08.034

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Design, synthesis, and in vitro evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors

Authors: Corrigan TS, Lotti Diaz LM, Border SE, Ratigan SC, Kasper KQ, Sojka D, Fajtova P, Caffrey CR, Salvesen GS, McElroy CA, Hadad CM, Doğan Ekici Ö

Journal: Journal of enzyme inhibition and medicinal chemistry

PubMed ID: 32633155

Doi: 10.1080/14756366.2020.1781107

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