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Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units

Authors: Uciel Chorostecki, Ester Saus, Toni Gabaldón

Journal: Comput Struct Biotechnol J

PubMed ID: 34141143

Doi: 10.1016/j.csbj.2021.05.045

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Lovastatin attenuates sevoflurane-induced cognitive disorder in aged rats via reducing Aβ accumulation

Authors: Ying Xu, Yunxia Dong, Cong Wang, Qian Jiang, Haichao Chu, Yue Tian

Journal: Neurochem Int

PubMed ID: 34048842

Doi: 10.1016/j.neuint.2021.105078

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Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system

Authors: Lenka Horváthová, Vojtěch Žárský, Tomáš Pánek, Romain Derelle, Jan Pyrih, Alžběta Motyčková, Veronika Klápšťová, Martina Vinopalová, Lenka Marková, Luboš Voleman, Vladimír Klimeš, Markéta Petrů, Zuzana Vaitová, Ivan Čepička, Klára Hryzáková, Karel Harant, Michael W Gray, Mohamed Chami, Ingrid Guilvout, Olivera Francetic, B Franz Lang, Čestmír Vlček, Anastasios D Tsaousis, Marek Eliáš, Pavel Doležal

Journal: Nat Commun

PubMed ID: 34011950

Doi: 10.1038/s41467-021-23046-7

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CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors

Authors: Ornella Manfra, Gaia Calamera, Alexander Froese, Dulasi Arunthavarajah, Nicoletta C Surdo, Silja Meier, Arne Olav Melleby, Monica Aasrum, Jan Magnus Aronsen, Viacheslav O Nikolaev, Manuela Zaccolo, Lise Román Moltzau, Finn Olav Levy, Kjetil Wessel Andressen

Journal: Cardiovasc Res

PubMed ID: 33970224

Doi: 10.1093/cvr/cvab167

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Subthreshold Nanosecond Laser, from Trials to Real-Life Clinical Practice: A Cohort Study

Authors: Hasan Chichan, Matthias Maus, Ludwig M Heindl

Journal: Clin Ophthalmol

PubMed ID: 33986589

Doi: 10.2147/OPTH.S307671

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Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification

Authors: Chenghui Zhou, Zhefang Wang, Jiahui Li, Xiaolin Wu, Ningbo Fan, Dai Li, Fanyu Liu, Patrick S Plum, Sascha Hoppe, Axel M Hillmer, Alexandar Quaas, Florian Gebauer, Seung-Hun Chon, Christiane J Bruns, Yue Zhao

Journal: Cancers (Basel)

PubMed ID: 34065695

Doi: 10.3390/cancers13102403

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Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development

Authors: Xiangmei Zhang, Igor Mandric, Kevin H Nguyen, Thao T T Nguyen, Matteo Pellegrini, James C R Grove, Steven Barnes, Xian-Jie Yang

Journal: Front Cell Dev Biol

PubMed ID: 34055784

Doi: 10.3389/fcell.2021.653305

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Novel serine/threonine-O-glycosylation with N-acetylneuraminic acid and 3-deoxy-D-manno-octulosonic acid by bacterial flagellin glycosyltransferases

Authors: Khairnar A, Sunsunwal S, Babu P, Ramya TNC

Journal: Glycobiology

PubMed ID: 32886756

Doi: 10.1093/glycob/cwaa084

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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

Authors: Koenraad Philippaert, Subha Kalyaanamoorthy, Mohammad Fatehi, Wentong Long, Shubham Soni, Nikole J Byrne, Amy Barr, Jyoti Singh, Jordan Wong, Taylor Palechuk, Chloe Schneider, Ahmed M Darwesh, Zaid H Maayah, John M Seubert, Khaled Barakat, Jason R B Dyck, Peter E Light

Journal: Circulation

PubMed ID: 33832341

Doi: 10.1161/CIRCULATIONAHA.121.053350

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Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis

Authors: Canan Kasikara, Maaike Schilperoort, Brennan Gerlach, Chenyi Xue, Xiaobo Wang, Ze Zheng, George Kuriakose, Bernhard Dorweiler, Hanrui Zhang, Gabrielle Fredman, Danish Saleheen, Muredach P Reilly, Ira Tabas

Journal: J Clin Invest

PubMed ID: 33630758

Doi: 10.1172/JCI145275

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