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Circular RNA TLK1 Promotes Sepsis-Associated Acute Kidney Injury by Regulating Inflammation and Oxidative Stress Through miR-106a-5p/HMGB1 Axis

Authors: Hai-Ping Xu, Xiao-Ying Ma, Chen Yang

Journal: Front Mol Biosci

PubMed ID: 34250012

Doi: 10.3389/fmolb.2021.660269

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Functional differences between TSHR alleles associate with variation in spawning season in Atlantic herring

Authors: Junfeng Chen, Huijuan Bi, Mats E Pettersson, Daiki X Sato, Angela P Fuentes-Pardo, Chunheng Mo, Shady Younis, Ola Wallerman, Patric Jern, Gregorio Molés, Ana Gómez, Gunnar Kleinau, Patrick Scheerer, Leif Andersson

Journal: Commun Biol

PubMed ID: 34172814

Doi: 10.1038/s42003-021-02307-7

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The lncRNA PVT1 regulates autophagy in regulatory T cells to suppress heart transplant rejection in mice by targeting miR-146a

Authors: Jian Lu, Xiaodong Wang, Baotong Zhang, Peiyuan Li, Xuezhi Du, Feng Qi

Journal: Cell Immunol

PubMed ID: 34214903

Doi: 10.1016/j.cellimm.2021.104400

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A novel multiplexed Enzyme-Linked Immunosorbent Assay for the detection of IgG seroreactivity to cytomegalovirus (CMV) UL144

Authors: H Miller, P Simpson, M Forman, A Prigan, S Kehl, B Mesich, M Faron, N Ledeboer, R Arav-Boger

Journal: J Clin Microbiol

PubMed ID: 34076473

Doi: 10.1128/JCM.00964-21

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Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides

Authors: Bing Wang, Vladimir Svetlov, Yuri I Wolf, Eugene V Koonin, Evgeny Nudler, Irina Artsimovitch

Journal: MBio

PubMed ID: 34154407

Doi: 10.1128/mBio.01423-21

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Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin

Authors: Ian A Durie, John V Dzimianski, Courtney M Daczkowski, Jack McGuire, Kay Faaberg, Scott D Pegan

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34196620

Doi: 10.1107/S205979832100509X

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Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection

Authors: Fouad S El-Mayet, Kelly S Harrison, Clinton Jones

Journal: Viruses

PubMed ID: 34203849

Doi: 10.3390/v13061148

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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Authors: Shirish Shukla, Weijiang Ying, Felicia Gray, Yiwu Yao, Miranda L Simes, Qingjie Zhao, Hongzhi Miao, Hyo Je Cho, Paula González-Alonso, Alyssa Winkler, George Lund, Trupta Purohit, EunGi Kim, Xiaotian Zhang, Joshua M Ray, Shihan He, Caroline Nikolaidis, Juliano Ndoj, Jingya Wang, Łukasz Jaremko, Mariusz Jaremko, Russell J H Ryan, Monica L Guzman, Jolanta Grembecka, Tomasz Cierpicki

Journal: Nat Chem Biol

PubMed ID: 34155404

Doi: 10.1038/s41589-021-00815-5

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Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Authors: Ruoke Wang, Qi Zhang, Jiwan Ge, Wenlin Ren, Rui Zhang, Jun Lan, Bin Ju, Bin Su, Fengting Yu, Peng Chen, Huiyu Liao, Yingmei Feng, Xuemei Li, Xuanling Shi, Zheng Zhang, Fujie Zhang, Qiang Ding, Tong Zhang, Xinquan Wang, Linqi Zhang

Journal: Immunity

PubMed ID: 34166623

Doi: 10.1016/j.immuni.2021.06.003

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Multiplexed engineering glycosyltransferase genes in CHO cells via targeted integration for producing antibodies with diverse complex-type N-glycans

Authors: Ngan T B Nguyen, Jianer Lin, Shi Jie Tay, Jessna Yeo, Terry Nguyen-Khuong, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 34155258

Doi: 10.1038/s41598-021-92320-x

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