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Heterozygous gain-of-function variants cause an autoinflammatory immunodeficiency
Authors: Thomas Magg, Tsubasa Okano, Lars M Koenig, Daniel F R Boehmer, Samantha L Schwartz, Kento Inoue, Jennifer Heimall, Francesco Licciardi, Julia Ley-Zaporozhan, Ronald M Ferdman, Andrés Caballero-Oteyza, Esther N Park, Brenda M Calderon, Debayan Dey, Hirokazu Kanegane, Kazutoshi Cho, Davide Montin, Karl Reiter, Matthias Griese, Michael H Albert, Meino Rohlfs, Paul Gray, Christoph Walz, Graeme L Conn, Kathleen E Sullivan, Christoph Klein, Tomohiro Morio, Fabian Hauck
Journal: Sci Immunol
PubMed ID: 34145065
Doi: 10.1126/sciimmunol.abf9564
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Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species
Authors: Ruoke Wang, Qi Zhang, Jiwan Ge, Wenlin Ren, Rui Zhang, Jun Lan, Bin Ju, Bin Su, Fengting Yu, Peng Chen, Huiyu Liao, Yingmei Feng, Xuemei Li, Xuanling Shi, Zheng Zhang, Fujie Zhang, Qiang Ding, Tong Zhang, Xinquan Wang, Linqi Zhang
Journal: Immunity
PubMed ID: 34166623
Doi: 10.1016/j.immuni.2021.06.003
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Direct Observation of the Self-Aggregation of R3R4 Bi-repeat of Tau Protein
Authors: Parvathy Jayan, Arshad A Vahid, Safwa T Kizhakkeduth, Shafeek O H Muhammed, Ajmala B Shibina, Vinesh Vijayan
Journal: Chembiochem
PubMed ID: 33826208
Doi: 10.1002/cbic.202100013
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Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
Authors: Jenn-Haung Lai, De-Wei Wu, Chien-Hsiang Wu, Li-Feng Hung, Chuan-Yueh Huang, Shuk-Man Ka, Ann Chen, Zee-Fen Chang, Ling-Jun Ho
Journal: iScience
PubMed ID: 34142025
Doi: 10.1016/j.isci.2021.102498
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YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways
Authors: Wen-Bin Ou, Meijun Z Lundberg, Shuihao Zhu, Nacef Bahri, Anastasios Kyriazoglou, Liangliang Xu, Ting Chen, Adrian Mariño-Enriquez, Jonathan A Fletcher
Journal: Oncogenesis
PubMed ID: 33947829
Doi: 10.1038/s41389-021-00327-w
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Nanomolar Pulse Dipolar EPR Spectroscopy in Proteins: Cu-Cu and Nitroxide-Nitroxide Cases
Authors: Katrin Ackermann, Joshua L Wort, Bela E Bode
Journal: J Phys Chem B
PubMed ID: 33998795
Doi: 10.1021/acs.jpcb.1c03666
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Bioinformatic prediction and identification of immunogenic epitopes of the antigenic 14-3-3 protein of Echinococcus multilocularis
Authors: Wei Wei, Lei Wang, Pei Zhou, Baili Jiang, Haisheng Liu, Lin Feng, Ri-Li Ge, Feng Tang, Runle Li
Journal: Acta Trop
PubMed ID: 33979643
Doi: 10.1016/j.actatropica.2021.105955
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Insect High FiveTM cell line development using site-specific flipase recombination technology
Authors: Mafalda M Dias, João Vidigal, Daniela P Sequeira, Paula M Alves, Ana P Teixeira, António Roldão
Journal: G3 (Bethesda)
PubMed ID: 33982066
Doi: 10.1093/g3journal/jkab166
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Structural and Biophysical Properties of Supercharged and Circularized Nanodiscs
Authors: Nicolai Tidemand Johansen, Alessandra Luchini, Frederik Grønbæk Tidemand, Simone Orioli, Anne Martel, Lionel Porcar, Lise Arleth, Martin Cramer Pedersen
Journal: Langmuir
PubMed ID: 34038130
Doi: 10.1021/acs.langmuir.1c00560
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SpRY Cas9 Can Utilize a Variety of Protospacer Adjacent Motif Site Sequences To Edit the Candida albicans Genome
Authors: Ben A Evans, Douglas A Bernstein
Journal: mSphere
PubMed ID: 34011687
Doi: 10.1128/mSphere.00303-21
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