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Comparative pharmacological characterization of D1-like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatussuggests pleiotropic signaling in mosquito vector lineages

Authors: Catherine A. Hill, Trevor Doyle, Andrew B. Nuss, Karin F. K. Ejendal, Jason M. Meyer & Val J. Watts

Journal: Parasites & Vectors

Doi: 10.1186/s13071-016-1477-6

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pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants.

Authors: MuruganElavazhagan，VenkatramanAnandalakshmi，LeiZhou，MouvetVictoria，Rui Yi LimRayne，MurugananthamNandhakumar，GohEunice，Swee Lim PehGary，BeuermanRoger W，ChaurasiaShyam S，RajamaniLakshminarayanan，MehtaJodhb

Journal: Sci Rep

PubMed ID: 27030015

Doi: 10.1038/srep23836

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Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells.

Authors: CherianJoseph，NacroKassoum，PohZhi Ying，GuoSamantha，JeyarajDuraiswamy A，WongYun Xuan，HoMelvyn，YangHai Yan，JoyJoma Kanikadu，KwekZekui Perlyn，LiuBoping，WeeJohn Liang Kuan，OngEsther H Q，ChoongMeng Ling，PoulsenAnders，LeeMay Ann，PendharkarVishal，DingLi Jun，ManoharanVithya，ChewYun Shan，SangthongpitagKanda，LimSharon，OngS Tiong，HillJeffrey，KellerThom

Journal: J. Med. Chem.

PubMed ID: 27011159

Doi: 10.1021/acs.jmedchem.5b01712

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Antibody-antigen kinetics constrain intracellular humoral immunity.

Authors: BottermannMaria，LodeHeidrun Elisabeth，WatkinsonRuth E，FossStian，SandlieInger，AndersenJan Terje，JamesL

Journal: Sci Rep

PubMed ID: 27881870

Doi: 10.1038/srep37457

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Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.

Authors: Smith D, Tikhonova IG, Jewhurst HL, Drysdale OC, Dvořák J, Robinson MW, Cwiklinski K, Dalton JP.

Journal: J Biol Chem

PubMed ID: 27422822

Doi: 10.1074/jbc.M116.724344

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A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

Authors: Tan J, Pieper K, Piccoli L, Abdi A, Perez MF, Geiger R, Tully CM, Jarrossay D, Maina Ndungu F, Wambua J, Bejon P, Fregni CS, Fernandez-Rodriguez B, Barbieri S, Bianchi S, Marsh K, Thathy V, Corti D, Sallusto F, Bull P, Lanzavecchia A

Journal: Nature

PubMed ID: 26700814

Doi: 10.1038/nature16450

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Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA.

Authors: ThiEmily P，LeeAmy C H，GeisbertJoan B，Ursic-BedoyaRaul，AgansKrystle N，RobbinsMarjorie，DeerDaniel J，FentonKarla A，KondratowiczAndrew S，MacLachlanIan，GeisbertThomas W，MireCh

Journal: Nat Microbiol

PubMed ID: 27670117

Doi: 10.1038/nmicrobiol.2016.142

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miR-26a induced the suppression of tumor growth of cholangiocarcinoma via KRT19 approach.

Authors: WangPing，Lv

Journal: Oncotarget

PubMed ID: 27833076

Doi: 10.18632/oncotarget.13229

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Generation of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies.

Authors: JahnLorenz，van der SteenDirk M，HagedoornRenate S，HombrinkPleun，KesterMichel G D，SchoonakkerMarjolein P，de RidderDaniëlle，van VeelenPeter A，FalkenburgJ H Frederik，HeemskerkMirjam

Journal: Oncotarget

PubMed ID: 27776339

Doi: 10.18632/oncotarget.12778

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Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha.

Authors: AoXiang，LiShujing，XuZhaowei，YangYangyang，ChenMin，JiangXiao，WuHui

Journal: Oncotarget

PubMed ID: 27028856

Doi: 10.18632/oncotarget.8354

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