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Mycobacterium tuberculosis ClpC1 N-Terminal Domain Is Dispensable for Adaptor Protein-Dependent Allosteric Regulation.

Authors: Marsee JD, Ridings A, Yu T, Miller JM.

Journal: Int J Mol Sci

PubMed ID: 30463272

Doi: 10.3390/ijms19113651

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Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase.

Authors: Walton CJW,, Thiebaut F,, Brunzelle JS, Couture JF,, Chica RA,.

Journal: Biochemistry

PubMed ID: 30153007

Doi: 10.1021/acs.biochem.8b00767

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An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex.

Authors: Kawauchi K, Sugimoto W, Yasui T, Murata K, Itoh K, Takagi K, Tsuruoka T, Akamatsu K, Tateishi-Karimata H, Sugimoto N, Miyoshi D.

Journal: Nat Commun

PubMed ID: 29891945

Doi: 10.1038/s41467-018-04771-y

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Mutagenesis of an Active-Site Loop in Tryptophan Hydroxylase Dramatically Slows the Formation of an Early Intermediate in Catalysis.

Authors: Subedi BP, Fitzpatrick PF.

Journal: J Am Chem Soc

PubMed ID: 29589922

Doi: 10.1021/jacs.8b00936

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Soluble Zwitterionic Poly(sulfobetaine) Destabilizes Proteins.

Authors: Kisley L, Serrano KA, Davis CM, Guin D, Murphy EA, Gruebele M, Leckband DE.

Journal: Biomacromolecules

PubMed ID: 30064224

Doi: 10.1021/acs.biomac.8b01120

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Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Authors: Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Journal: Cell Chem Biol

PubMed ID: 30344053

Doi: 10.1016/j.chembiol.2018.09.012

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PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.

Authors: Georgilis Athena，Klotz Sabrina，Hanley Christopher J，Herranz Nicolas，Weirich Benedikt，Morancho Beatriz，Leote Ana Carolina，D'Artista Luana，Gallage Suchira，Seehawer Marco，Carroll Thomas，Dharmalingam Gopuraja，Wee Keng Boon，Mellone Marco，Pombo Joaquim，Heide Danijela，Guccione Ernesto，Arribas Joaquín，Barbosa-Morais Nuno L，Heikenwalder Mathias，Thomas Gareth J，Zender Lars，Gil Je

Journal: Cancer Cell

PubMed ID: 29990503

Doi: 10.1016/j.ccell.2018.06.007

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LncRNA ZEB1-AS1/miR-409-3p/ZEB1 feedback loop is involved in the progression of non-small cell lung cancer.

Authors: Qu R, Chen X, Zhang C.

Journal: Biochem Biophys Res Commun

PubMed ID: 30448056

Doi: 10.1016/j.bbrc.2018.11.059

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Discovery and Characterization of VU0529331， a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated， Inwardly Rectifying， Potassium (GIRK) Channels.

Authors: KozekKrystian A，DuYu，SharmaSwagat，PraelFrancis J，SpitznagelBrittany D，KharadeSujay V，DentonJerod S，HopkinsCorey R，WeaverC D

Journal: ACS Chem Neurosci

PubMed ID: 30136838

Doi: 10.1021/acschemneuro.8b00287

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.

Authors: HouYuzhu，LiangHua，RaoEnyu，ZhengWenxin，HuangXiaona，DengLiufu，ZhangYuan，YuXinshuang，XuMeng，MauceriHelena，ArinaAinhoa，WeichselbaumRalph R，FuYang

Journal: Immunity

PubMed ID: 30170810

Doi: 10.1016/j.immuni.2018.07.008

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