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De novo design of a fluorescence-activating β-barrel.

Authors: Dou J,, Vorobieva AA,, Sheffler W,, Doyle LA, Park H,, Bick MJ,, Mao B,, Foight GW, Lee MY, Gagnon LA, Carter L,, Sankaran B, Ovchinnikov S,,, Marcos E,,, Huang PS,,, Vaughan JC, Stoddard BL, Baker D,,.

Journal: Nature

PubMed ID: 30209393

Doi: 10.1038/s41586-018-0509-0

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Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.

Authors: Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M.

Journal: J Allergy Clin Immunol

PubMed ID: 29128673

Doi: 10.1016/j.jaci.2017.08.044

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Mycobacterium tuberculosis ClpC1 N-Terminal Domain Is Dispensable for Adaptor Protein-Dependent Allosteric Regulation.

Authors: Marsee JD, Ridings A, Yu T, Miller JM.

Journal: Int J Mol Sci

PubMed ID: 30463272

Doi: 10.3390/ijms19113651

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Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase.

Authors: Walton CJW,, Thiebaut F,, Brunzelle JS, Couture JF,, Chica RA,.

Journal: Biochemistry

PubMed ID: 30153007

Doi: 10.1021/acs.biochem.8b00767

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An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex.

Authors: Kawauchi K, Sugimoto W, Yasui T, Murata K, Itoh K, Takagi K, Tsuruoka T, Akamatsu K, Tateishi-Karimata H, Sugimoto N, Miyoshi D.

Journal: Nat Commun

PubMed ID: 29891945

Doi: 10.1038/s41467-018-04771-y

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Mutagenesis of an Active-Site Loop in Tryptophan Hydroxylase Dramatically Slows the Formation of an Early Intermediate in Catalysis.

Authors: Subedi BP, Fitzpatrick PF.

Journal: J Am Chem Soc

PubMed ID: 29589922

Doi: 10.1021/jacs.8b00936

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Soluble Zwitterionic Poly(sulfobetaine) Destabilizes Proteins.

Authors: Kisley L, Serrano KA, Davis CM, Guin D, Murphy EA, Gruebele M, Leckband DE.

Journal: Biomacromolecules

PubMed ID: 30064224

Doi: 10.1021/acs.biomac.8b01120

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Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Authors: Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Journal: Cell Chem Biol

PubMed ID: 30344053

Doi: 10.1016/j.chembiol.2018.09.012

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PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.

Authors: Georgilis Athena，Klotz Sabrina，Hanley Christopher J，Herranz Nicolas，Weirich Benedikt，Morancho Beatriz，Leote Ana Carolina，D'Artista Luana，Gallage Suchira，Seehawer Marco，Carroll Thomas，Dharmalingam Gopuraja，Wee Keng Boon，Mellone Marco，Pombo Joaquim，Heide Danijela，Guccione Ernesto，Arribas Joaquín，Barbosa-Morais Nuno L，Heikenwalder Mathias，Thomas Gareth J，Zender Lars，Gil Je

Journal: Cancer Cell

PubMed ID: 29990503

Doi: 10.1016/j.ccell.2018.06.007

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LncRNA ZEB1-AS1/miR-409-3p/ZEB1 feedback loop is involved in the progression of non-small cell lung cancer.

Authors: Qu R, Chen X, Zhang C.

Journal: Biochem Biophys Res Commun

PubMed ID: 30448056

Doi: 10.1016/j.bbrc.2018.11.059

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