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Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery
Authors: Ferdinando M Milazzo, Antonio Chaves-Sanjuan, Olga Minenkova, Daniela Santapaola, Anna M Anastasi, Gianfranco Battistuzzi, Caterina Chiapparino, Antonio Rosi, Emilio Merlo Pich, Claudio Albertoni, Emanuele Marra, Laura Luberto, Cécile Viollet, Luigi G Spagnoli, Anna Riccio, Antonio Rossi, M Gabriella Santoro, Federico Ballabio, Cristina Paissoni, Carlo Camilloni, Martino Bolognesi, Rita De Santis
Journal: Mol Ther
PubMed ID: 36114671
Doi: 10.1016/j.ymthe.2022.09.010
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Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis
Authors: Govind Kunduri, Si-Hung Le, Valentina Baena, Nagampalli Vijaykrishna, Adam Harned, Kunio Nagashima, Daniel Blankenberg, Izumi Yoshihiro, Kedar Narayan, Takeshi Bamba, Usha Acharya, Jairaj K Acharya
Journal: PLoS Biol
PubMed ID: 36170207
Doi: 10.1371/journal.pbio.3001599
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Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes
Authors: Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola, Björn Schulte, Kristin G Monaghan, Amber Begtrup, Annalaura Torella, Michele Pinelli, Anne Sophie Denommé-Pichon, Antonio Vitobello, Caroline Racine, Maria Margherita Mancardi, Courtney Kiss, Andrea Guerin, Wendy Wu, Elisabeth Gabau Vila, Bryan C Mak, Julian A Martinez-Agosto, Michael B Gorin, Bugrahan Duz, Yavuz Bayram, Claudia M B Carvalho, Jaime E Vengoechea, David Chitayat, Tiong Yang Tan, Bert Callewaert, Bernd Kruse, Lynne M Bird, Laurence Faivre, Marcella Zollino, Saskia Biskup, Pasquale Striano, Vincenzo Nigro, Mariasavina Severino, Valeria Capra, Gregory Costain, Koh Ichi Nagata
Journal: Brain
PubMed ID: 35851598
Doi: 10.1093/brain/awac106
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Structural Basis of Substrate Promiscuity and Catalysis by the Reverse Prenyltransferase -Dimethylallyl-l-tryptophan Synthase from
Authors: Samuel A Eaton, Trey A Ronnebaum, Benjamin W Roose, David W Christianson
Journal: Biochemistry
PubMed ID: 36084241
Doi: 10.1021/acs.biochem.2c00350
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Proton-transporting heliorhodopsins from marine giant viruses
Authors: Shoko Hososhima, Ritsu Mizutori, Rei Abe-Yoshizumi, Andrey Rozenberg, Shunta Shigemura, Alina Pushkarev, Masae Konno, Kota Katayama, Keiichi Inoue, Satoshi P Tsunoda, Oded Béjà, Hideki Kandori
Journal: Elife
PubMed ID: 36065640
Doi: 10.7554/eLife.78416
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Characteristics of NtCCD1-3 from tobacco, and protein engineering of the CCD1 to enhance -ionone production in yeast
Authors: Xiaowei Gong, Fan Li, Yupeng Liang, Xiulin Han, Mengliang Wen
Journal: Front Microbiol
PubMed ID: 36212872
Doi: 10.3389/fmicb.2022.1011297
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Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma
Authors: James M Cleary, Betty Rouaisnel, Antoine Daina, Srivatsan Raghavan, Lauren A Roller, Brandon M Huffman, Harshabad Singh, Patrick Y Wen, Nabeel Bardeesy, Vincent Zoete, Brian M Wolpin, Julie-Aurore Losman
Journal: NPJ Precis Oncol
PubMed ID: 36056177
Doi: 10.1038/s41698-022-00304-5
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Utilization of Receptor-Binding Domain of SARS-CoV-2 Spike Protein Expressed in Escherichia coli for the Development of Neutralizing Antibody Assay
Authors: Termsak Tantiwiwat, Apisitt Thaiprayoon, Ake-Kavitch Siriatcharanon, Chakrit Tachaapaikoon, Nongluk Plongthongkum, Dujduan Waraho-Zhmayev
Journal: Mol Biotechnol
PubMed ID: 36103078
Doi: 10.1007/s12033-022-00563-4
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The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues
Authors: Sinan Gai, Kajitha Suthagar, Karl J Shaffer, Wanting Jiao, Yacoba V T Minnow, Kayla Glockzin, Sean W Maatouk, Ardala Katzfuss, Thomas D Meek, Vern L Schramm, Peter C Tyler
Journal: Bioorg Med Chem
PubMed ID: 36209571
Doi: 10.1016/j.bmc.2022.117038
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PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells
Authors: Yan Feng, Xu Zhang, Songfa Zhang, Shanshan Xu, Xiaojing Chen, Caiyun Zhou, Yongmei Xi, Xing Xie, Weiguo Lu
Journal: Front Biosci (Landmark Ed)
PubMed ID: 36224008
Doi: 10.31083/j.fbl2709262
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