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Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase.
Authors: Walton CJW,, Thiebaut F,, Brunzelle JS, Couture JF,, Chica RA,.
Journal: Biochemistry
PubMed ID: 30153007
Doi: 10.1021/acs.biochem.8b00767
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An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex.
Authors: Kawauchi K, Sugimoto W, Yasui T, Murata K, Itoh K, Takagi K, Tsuruoka T, Akamatsu K, Tateishi-Karimata H, Sugimoto N, Miyoshi D.
Journal: Nat Commun
PubMed ID: 29891945
Doi: 10.1038/s41467-018-04771-y
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A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.
Authors: Michel BC,,, D'Avino AR,, Cassel SH,,,, Mashtalir N,, McKenzie ZM, McBride MJ,,, Valencia AM,,, Zhou Q, Bocker M, Soares LMM, Pan J,,, Remillard DI,, Lareau CA,, Zullow HJ,,,, Fortoul N, Gray NS, Bradner JE,, Chan HM, Kadoch C,.
Journal: Nat Cell Biol
PubMed ID: 30397315
Doi: 10.1038/s41556-018-0221-1
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X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Authors: Järvå M, Lay FT, Phan TK, Humble C, Poon IKH, Bleackley MR, Anderson MA, Hulett MD, Kvansakul M.
Journal: Nat Commun
PubMed ID: 29773800
Doi: 10.1038/s41467-018-04434-y
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Novel Role of p53 in Septic Immunosuppression: Involvement in Loss and Dysfunction of CD4+ T Lymphocytes.
Authors: Zhang H, Xu CF, Ren C, Wu TT, Dong N, Yao YM.
Journal: Cell Physiol Biochem
PubMed ID: 30453300
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Biochemical Characterization of Aspergillus fumigatus AroH, a Putative Aromatic Amino Acid Aminotransferase.
Authors: Dindo M, Costanzi E, Pieroni M, Costantini C, Annunziato G, Bruno A,, Keller NP, Romani L, Zelante T, Cellini B.
Journal: Front Mol Biosci
PubMed ID: 30547035
Doi: 10.3389/fmolb.2018.00104
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A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance.
Authors: Berland S, Toft-Bertelsen TL, Aukrust I, Byska J, Vaudel M,, Bindoff LA,, MacAulay N, Houge G.
Journal: Cold Spring Harb Mol Case Stud
PubMed ID: 29437797
Doi: 10.1101/mcs.a002303
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MicroRNA-421 suppresses the apoptosis and autophagy of hippocampal neurons in epilepsy mice model by inhibition of the TLR/MYD88 pathway.
Authors: Wen X,, Han XR,, Wang YJ,, Wang S,, Shen M,, Zhang ZF,, Fan SH,, Shan Q,, Wang L,, Li MQ,, Hu B,, Sun CH,, Wu DM,, Lu J,, Zheng YL,.
Journal: J Cell Physiol
PubMed ID: 29380367
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De novo design of a fluorescence-activating β-barrel.
Authors: Dou J,, Vorobieva AA,, Sheffler W,, Doyle LA, Park H,, Bick MJ,, Mao B,, Foight GW, Lee MY, Gagnon LA, Carter L,, Sankaran B, Ovchinnikov S,,, Marcos E,,, Huang PS,,, Vaughan JC, Stoddard BL, Baker D,,.
Journal: Nature
PubMed ID: 30209393
Doi: 10.1038/s41586-018-0509-0
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Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.
Authors: Bigley V, Maisuria S, Cytlak U, Jardine L, Care MA, Green K, Gunawan M, Milne P, Dickinson R, Wiscombe S, Parry D, Doffinger R, Laurence A, Fonseca C, Stoevesandt O, Gennery A, Cant A, Tooze R, Simpson AJ, Hambleton S, Savic S, Doody G, Collin M.
Journal: J Allergy Clin Immunol
PubMed ID: 29128673
Doi: 10.1016/j.jaci.2017.08.044
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