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Identification and biochemical characterization of a novel exo-type β-agarase Aga3463 from an Antarctic Pseudoalteromonas sp. strain.
Authors: LiJiang，XieMaisheng，Gao
Journal: Int. J. Biol. Macromol.
PubMed ID: 30710591
Doi: 10.1016/j.ijbiomac.2019.01.204
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An IQSEC2 Mutation Associated With Intellectual Disability and Autism Results in Decreased Surface AMPA Receptors.
Authors: RogersEli J，JadaReem，Schragenheim-RozalesKinneret，SahMegha，CortesMarisol，FlorenceMatthew，LevyNina S，MossRachel，WalikonisRandall S，PaltyRaz，ShalgiReut，LichtmanDaniela，KavushanskyAlexandra，GergesNashaat Z，KahnItamar，UmanahGeorge K E，LevyAndr
Journal: Front Mol Neurosci
PubMed ID: 30842726
Doi: 10.3389/fnmol.2019.00043
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Homozygous frame shift variant in ATP7B exon 1 leads to bypass of nonsense-mediated mRNA decay and to a protein capable of copper export.
Authors: StalkeAmelie，PfisterEva-Doreen，BaumannUlrich，EilersMarlies，SchäfferVera，IlligThomas，AuberBernd，SchlegelbergerBrigitte，BrackmannRenate，ProkischHolger，KroossSimon，BohneJens，SkawranBr
Journal: Eur. J. Hum. Genet.
PubMed ID: 30723317
Doi: 10.1038/s41431-019-0345-1
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Whole-exome sequencing of ovarian cancer families uncovers putative predisposition genes.
Authors: Zhu Qianqian，Zhang Jianmin，Chen Yanmin，Hu Qiang，Shen He，Huang Ruea-Yea，Liu Qian，Kaur Jasmine，Long Mark，Battaglia Sebastiano，Eng Kevin H，Lele Shashikant B，Zsiros Emese，Villella Jeannine，Lugade Amit，Yao Song，Liu Song，Moysich Kirsten，Odunsi Kun
Journal: Int. J. Cancer
PubMed ID: 31265121
Doi: 10.1002/ijc.32545
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Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT).
Authors: ZwartsenAnne，LitjensCarlijn H C，HondebrinkLaura，van den HeuvelJeroen J M W，GreupinkRick，RusselFrans G M，de LangeDylan W，LeglerJuliette，KoenderinkJan B，WesterinkRemco
Journal: Toxicology
PubMed ID: 31009648
Doi: 10.1016/j.tox.2019.04.012
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Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Authors: AnantharajanJothi，ZhouHengbo，ZhangLingdi，HotzTaylor，VincentMelanie Y，BlevinsMelanie A，JanssonAnna E，KuanJohn Wee Liang，NgElizabeth Yihui，YeoYee Khoon，BaburajendranNithya，LinGrace，HungAlvin W，JoyJoma，PatnaikSamarjit，MaruganJuan，RudraPratyaydipta，GhoshDebashis，HillJeffrey，KellerThomas H，ZhaoRui，FordHeide L，KangCon
Journal: Mol. Cancer Ther.
PubMed ID: 31285279
Doi: 10.1158/1535-7163.MCT-18-1239
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microRNA-505 negatively regulates HMGB1 to suppress cell proliferation in renal cell carcinoma.
Authors: ZhongBing，QinZhiqiang，ZhouHui，YangFengming，WeiKe，JiangXi，JiaRui
Journal: J. Cell. Physiol.
PubMed ID: 30644098
Doi: 10.1002/jcp.28142
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Highlight article: Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.
Authors: StrayerAmy L，Dennys-RiversCassandra N，RicartKarina C，BaeNarae，BeckmanJoseph S，FrancoMaria Clara，EstevezAlva
Journal: Exp. Biol. Med. (Maywood)
PubMed ID: 31142143
Doi: 10.1177/1535370219853798
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Rare variant significantly alters de novo ceramide synthesis pathway.
Authors: BlackburnNicholas B，MichaelLaura F，MeiklePeter J，PeraltaJuan M，MosiorMarian，McAhrenScott，BuiHai H，BellingerMelissa A，GilesCorey，KumarSatish，LeandroAna C，AlmeidaMarcio，WeirJacquelyn M，MahaneyMichael C，DyerThomas D，AlmasyLaura，VandeBergJohn L，Williams-BlangeroSarah，GlahnDavid C，DuggiralaRavindranath，KowalaMark，BlangeroJohn，CurranJoan
Journal: J. Lipid Res.
PubMed ID: 31227640
Doi: 10.1194/jlr.P094433
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Linker Dependence of Avidity in Multivalent Interactions between Disordered Proteins.
Authors: Sørensen Charlotte S，Jendroszek Agnieszka，Kjaergaard Ma
Journal: J. Mol. Biol.
PubMed ID: 31518611
Doi: 10.1016/j.jmb.2019.09.001
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