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Evolutionary insights into the stereoselectivity of imine reductases based on ancestral sequence reconstruction
Authors: Xin-Xin Zhu, Wen-Qing Zheng, Zi-Wei Xia, Xin-Ru Chen, Tian Jin, Xu-Wei Ding, Fei-Fei Chen, Qi Chen, Jian-He Xu, Xu-Dong Kong, Gao-Wei Zheng
Journal: Nat Commun
PubMed ID: 39609402
Doi: 10.1038/s41467-024-54613-3
Products & Services: Plasmid DNA Preparation   
Identification of an RNA-binding perturbing characteristic for thiopurine drugs and their derivatives to disrupt CELF1–RNA interaction
Authors: Yang Tan , Zhibo Zhao , Qingfang Han , Peipei Xu , Xiaopeng Shen , Yajun Jiang , Qiang Xu , Xingxin Wu
Journal: Nucleic Acids Research
PubMed ID: 39268573
Doi: 10.1093/nar/gkae788
Products & Services: Plasmid DNA Preparation   
Improvement and application of vacuum-infiltration system in tomato
Authors: Xinghao Yao, Ayat Taheri, Hang Liu, Yaojie Zhang, Ling Li, Jin Shao, Ke Wu, Qing Miao, Weizhi He, Xinyi Hu, Kexuan Tang
Journal: Horticulture research
Doi: doi.org/10.1093/hr/uhae197
Products & Services: Plasmid DNA Preparation   
Structure and genome editing of type I-B CRISPR-Cas
Authors: Meiling Lu, Chenlin Yu, Yuwen Zhang, Wenjun Ju, Zhi Ye, Chenyang Hua, Jinze Mao, Chunyi Hu, Zhenhuang Yang & Yibei Xiao
Journal: Nat Commun
PubMed ID: 38750051
Doi: 10.1038/s41467-024-48598-2
CRISPR/Cas13a-based supersensitive circulating tumor DNA assay for detecting EGFR mutations in plasma
Authors: Li Wang , Xiaosha Wen , Yang Yang , Zheng Hu , Jing Jiang , Lili Duan , Xiaofen Liao , Yan He , Yaru Liu , Jing Wang , Zhikun Liang , Xiaoya Zhu , Quan Liu , Tiancai Liu , Dixian Luo
Journal: Commun Biol
PubMed ID: 38806596
Doi: 10.1038/s42003-024-06368-2
Products & Services: Plasmid DNA Preparation   
Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes
Authors: Fleur Chapus 1, Guillaume Giraud 2, Pélagie Huchon 3, Mélanie Rodà 2, Xavier Grand 2, Caroline Charre 4, Chloé Goldsmith 5, Armando Andres Roca Suarez 2, Maria-Guadalupe Martinez 1, Judith Fresquet 6, Audrey Diederichs 3, Maëlle Locatelli 1, Hélène Polvèche 7, Caroline Scholtès 8, Isabelle Chemin 2, Hector Hernandez Vargas 5, Michel Rivoire 9, Cyril F Bourgeois 10, Fabien Zoulim 11, Barbara Testoni 12
Journal: J Hepatol
PubMed ID: 38782119
Doi: doi: 10.1016/j.jhep.2024.05.016.
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Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid
Authors: Huaying Zhao, Abdullah M Syed, Mir M Khalid, Ai Nguyen, Alison Ciling, Di Wu, Wai-Ming Yau, Sanjana Srinivasan, Dominic Esposito, Jennifer A Doudna, Grzegorz Piszczek, Melanie Ott, Peter Schuck
Journal: Nucleic Acids Res
PubMed ID: 38587193
Doi: 10.1093/nar/gkae256
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A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
Authors: Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
Journal: Nature
PubMed ID: 38509117
Doi: 10.1038/s41467-024-46644-7
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A Synergistic Lipid Nanoparticle Encapsulating mRNA Shingles Vaccine Induces Potent Immune Responses and Protects Guinea Pigs from Viral Challenges
Authors: Xingdi Cheng 1 2, Sujia Liu 3, Jing Sun 4, Lin Liu 3, Xinghuan Ma 3, Jingjiao Li 1 2, Bangda Fan 3, Chen Yang 1 2, Yuanyuan Zhao 1 2, Shuai Liu 1, Yixing Wen 1 2, Wei Li 1 2, Simin Sun 1, Shiwei Mi 1 2, Haonan Huo 1 2, Lei Miao 5, Hao Pan 6, Xiaolan Cui 4, Jiaqi Lin 3, Xueguang Lu 1 2
Journal: Adv Mater
PubMed ID: 38145557
Doi: 10.1002/adma.20231088
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Persistent immune imprinting occurs after vaccination with the COVID-19 XBB.1.5 mRNA booster in humans
Authors: M Alejandra Tortorici, Amin Addetia, Albert J Seo, Jack Brown, Kaiti Sprouse, Jenni Logue, Erica Clark, Nicholas Franko, Helen Chu, David Veesler
Journal: Immunity
PubMed ID: 38490197
Doi: 10.1016/j.immuni.2024.02.016
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