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Thermodynamic Profiling Reveals DNA Polymerase Template Binding, Substrate Incorporation, and Exonuclease Function

Authors: Yaping Sun, Wu Lin, Kang Fu, Jie Gao, Xianhui Zhao, Yun He, Hui Tian

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms262411909

Products & Services: Gene Synthesis Plasmid DNA Preparation Proteins, Expression, Isolation and Analysis Single-Stranded DNA Synthesis

Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents

Authors: Yichen Jiang, Qi Liu, Ting Zhu, Ruiguo Liang, Yujiao Qin, Xiya Guo, Jiacheng Wang, Ping Li, Jie Zhou, Han Ju, Mingxin Dong

Journal: European Journal of Medicinal Chemistry

PubMed ID: 41386205

Doi: 10.1016/j.ejmech.2025.118410

Products & Services: Plasmid DNA Preparation

Journal of Controlled Release

Authors: Fei Li, Quan Wang, Tingting Wang, Chen Xiong, Ziling Chen, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Shixuan Wang, Meng Wu, Jun Dai

Journal: Journal of controlled release

Doi: 10.1016/j.jconrel.2025.114337

Products & Services: Plasmid DNA Preparation

Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform

Authors: Ziguo Song, Junfan Guo, Zhanqing Fan, Shuhong Huang, Guanglei Li, Zichang Zhao, Bingchun Chen, Shisheng Huang, Wenxin Zheng, Yinghui Wei, Yulin Chen, Xingxu Huang, Jianghuai Liu, Lina Wu, Xiaolong Wang

Journal: Nature Communications

PubMed ID: 41152217

Doi: 10.1038/s41467-025-64562-0

Products & Services: Plasmid DNA Preparation

Protein M fusion proteins and uses

Authors: Jay Dela Cruz , Moreno Valley , CA

Journal: U.S. Patent

Doi: US11401309B2

Products & Services: Gene Synthesis Plasmid DNA Preparation Catalog Antibody Codon Optimization

Direct Observation of Secondary Nucleation in Huntingtin Amyloid Formation by High-Speed Atomic Force Microscopy

Authors: Chris van Ewijk, Greeshma Jain, Yari K Knelissen, Sourav Maity, Patrick C A van der Wel, Wouter H Roos

Journal: J Am Chem Soc

PubMed ID: 40505012

Doi: 10.1021/jacs.5c05571

Products & Services: Plasmid DNA Preparation

Histidine-Specific Modification of Chitin-Binding protein21 via Visible Light-Mediated C–H Functionalization and Protein Ligation

Authors: Xinliang Liu, Ping Wang and Farong Ye

Journal: CCS Chemistry

Doi: 10.31635/ccschem.024.202404864

Products & Services: Gene Synthesis Plasmid DNA Preparation

Accurate Mapping of 5-Glyceryl-methylcytosine Using Nanopore Sequencing

Authors: Linting Wang, Baodan He, Zixin Wang, Liting Kang, Jianhuang Xue, Shuanghong Yan

Journal: Anal Chem

PubMed ID: 40314134

Doi: 10.1021/acs.analchem.5c00845

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CRISPR-Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide-RNAs

Authors: Benjamín Durán-Vinet, Jo-Ann L. Stanton, Gert-Jan Jeunen, Ulla von Ammon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

Journal: Environmental DNA

Doi: doi.org/10.1002/edn3.70105

Products & Services: Gene Synthesis Plasmid DNA Preparation Custom DNA/RNA Oligos Molecular Biology Reagents

Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates ﬁbrilinduced cellular stress

Authors: Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Tingting Chen, Raffaella Parlato, Giuseppe Portale, Amalia M. Dolga & Patrick C. A. van der Wel

Journal: Nat Commun

PubMed ID: 40234398

Doi: 10.1038/s41467-025-58691-9

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