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Fitness Costs of pfhrp2 and pfhrp3 Deletions Underlying Diagnostic Evasion in Malaria Parasites

Authors: Shalini Nair, Xue Li, Standwell C Nkhoma, Tim Anderson

Journal: J Infect Dis

PubMed ID: 35709327

Doi: 10.1093/infdis/jiac240

Products & Services: Plasmid DNA Preparation

De novo design of anti-tuberculosis agents using a structure-based deep learning method

Authors: Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Srinivas Oruganti, Rajgopal Srinivasan, Arijit Roy

Journal: J Mol Graph Model

PubMed ID: 36257148

Doi: 10.1016/j.jmgm.2022.108361

Products & Services: Plasmid DNA Preparation

AlphaFold version 20 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys-Cys) formation of functional significance for VIPR2

Authors: Kotaro Sakamoto, Satoshi Asano, Yukio Ago, Takatsugu Hirokawa

Journal: Biochem Biophys Res Commun

PubMed ID: 36332470

Doi: 10.1016/j.bbrc.2022.10.071

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Rat Group IIA Secreted Phospholipase A Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer's Disease

Authors: Adrijan Ivanušec, Jernej Šribar, Adrijana Leonardi, Maja Zorović, Marko Živin, Igor Križaj

Journal: Int J Mol Sci

PubMed ID: 36293221

Doi: 10.3390/ijms232012368

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Isobutanol production by combined and metabolic engineering

Authors: Mamta Gupta, Matthew Wong, Kamran Jawed, Kamil Gedeon, Hannah Barrett, Marcelo Bassalo, Clifford Morrison, Danish Eqbal, Syed Shams Yazdani, Ryan T Gill, Jiaqi Huang, Marc Douaisi, Jonathan Dordick, Georges Belfort, Mattheos A G Koffas

Journal: Metab Eng Commun

PubMed ID: 36325486

Doi: 10.1016/j.mec.2022.e00210

Products & Services: Plasmid DNA Preparation

A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with motor and cognitive decline

Authors: Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride

Journal: Elife

PubMed ID: 36205397

Doi: 10.7554/eLife.77568

Products & Services: Plasmid DNA Preparation

Upregulation of programmed cell death 1 by interferon gamma and its biological functions in human monocytes

Authors: Kittitach Sri-Ngern-Ngam, Pornlapat Keawvilai, Trairak Pisitkun, Tanapat Palaga

Journal: Biochem Biophys Rep

PubMed ID: 36275930

Doi: 10.1016/j.bbrep.2022.101369

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Discovery and functional characterization of the oncogenicity and targetability of a novel gene fusion in pediatric angiosarcoma

Authors: Payal Jain, Sudarshan Iyer, Joshua Straka, Lea F Surrey, Jennifer Pogoriler, Harry Han, Tiffany Smith, Christine Busch, Elizabeth Fox, Marilyn Li, Angela J Waanders, Adam Resnick, Monika A Davare

Journal: Cold Spring Harb Mol Case Stud

PubMed ID: 36307212

Doi: 10.1101/mcs.a006222

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A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers

Authors: Rongjie Cheng, Fanying Li, Maolei Zhang, Xin Xia, Jianzhuang Wu, Xinya Gao, Huangkai Zhou, Zhi Zhang, Nunu Huang, Xuesong Yang, Yaliang Zhang, Shunli Shen, Tiebang Kang, Zexian Liu, Feizhe Xiao, Hongwei Yao, Jianbo Xu, Chao Yan, Nu Zhang

Journal: Cell Res

PubMed ID: 36241718

Doi: 10.1038/s41422-022-00726-7

Products & Services: Plasmid DNA Preparation

Autophagic flux restoration enhances the antitumor efficacy of tumor infiltrating lymphocytes

Authors: Chaoting Zhang, Yizhe Sun, Shance Li, Luyan Shen, Xia Teng, Yefei Xiao, Nan Wu, Zheming Lu

Journal: J Immunother Cancer

PubMed ID: 36307150

Doi: 10.1136/jitc-2022-004868

Products & Services: Plasmid DNA Preparation