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The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders.

Authors: Fieten H, Gill Y, Martin AJ, Concilli M, Dirksen K, van Steenbeek FG, Spee B, van den Ingh TS, Martens EC, Festa P, Chesi G, van de Sluis B, Houwen RH, Watson AL, Aulchenko YS, Hodgkinson VL, Zhu S, Petris MJ, Polishchuk RS, Leegwater PA, Rothuizen J.

Journal: Dis Model Mech

PubMed ID: 26747866

Doi: 10.1242/dmm.020263

Products & Services: Mutagenesis Services

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.

Authors: SteichenJon M，KulpDaniel W，TokatlianTalar，EscolanoAmelia，DosenovicPia，StanfieldRobyn L，McCoyLaura E，OzorowskiGabriel，HuXiaozhen，KalyuzhniyOleksandr，BrineyBryan，SchiffnerTorben，GarcesFernando，FreundNatalia T，GitlinAlexander D，MenisSergey，GeorgesonErik，KubitzMichael，AdachiYumiko，JonesMeaghan，MutafyanAndrew A，YunDong Soo，MayerChristian T，WardAndrew B，BurtonDennis R，WilsonIan A，IrvineDarrell J，NussenzweigMichel C，SchiefWilli

Journal: Immunity

PubMed ID: 27617678

Doi: 10.1016/j.immuni.2016.08.016

Products & Services: Mutagenesis Services

The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer.

Authors: HartungAnne-Mette，SwensenJeff，UrizInaki E，LapinMorten，KristjansdottirKaren，PetersenUlrika S S，BangJeanne Mari V，GuerraBarbara，AndersenHenriette Skovgaard，DobrowolskiSteven F，CareyJohn C，YuPing，VaughnCecily，CalhounAmy，LarsenMartin R，DyrskjøtLars，StevensonDavid A，AndresenBra

Journal: PLoS Genet.

PubMed ID: 27195699

Doi: 10.1371/journal.pgen.1006039

Products & Services: Mutagenesis Services

The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin.

Authors: Maison C,, Bailly D,, Quivy JP,, Almouzni G,.

Journal: Nat Commun

PubMed ID: 27426629

Doi: 10.1038/ncomms12224

Products & Services: Mutagenesis Services

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens.

Authors: Wisniewski JA,, Traore DA,, Bannam TL,, Lyras D,, Whisstock JC,, Rood JI,.

Journal: Mol Microbiol

PubMed ID: 26560080

Doi: 10.1111/mmi.13270

Products & Services: Mutagenesis Services

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants.

Authors: Brenan L, Andreev A, Cohen O, Pantel S, Kamburov A, Cacchiarelli D, Persky NS, Zhu C, Bagul M, Goetz EM, Burgin AB, Garraway LA, Getz G, Mikkelsen TS, Piccioni F, Root DE, Johannessen CM.

Journal: Cell Rep

PubMed ID: 27760319

Doi: 10.1016/j.celrep.2016.09.061

Products & Services: Mutagenesis Services

Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making.

Authors: Thouvenot P,,, Ben Yamin B,,, Fourrière L,,, Lescure A, Boudier T, Del Nery E, Chauchereau A,,, Goldgar DE, Houdayer C,,, Stoppa-Lyonnet D,,, Nicolas A,,, Millot GA,,.

Journal: PLoS Genet

PubMed ID: 27272900

Doi: 10.1371/journal.pgen.1006096

Products & Services: Mutagenesis Services

A new group of eubacterial light-driven retinal-binding proton pumps with an unusual cytoplasmic proton donor

Authors: Harris A, Ljumovic M, Bondar AN, Shibata Y, Ito S, Inoue K, Kandori H, Brown LS.

Journal: Biochim Biophys Acta.

PubMed ID: 26260121

Products & Services: PCR Cloning and Subcloning Mutagenesis Services

Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis.

Authors: Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S.

Journal: Nat Commun