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N-glycosylation of the protein disulfide isomerase Pdi1 ensures full Ustilago maydis virulence.
Authors: Marín-Menguiano M, Moreno-Sánchez I, Barrales RR, Fernández-Álvarez A, Ibeas JI.
Journal: PLoS Pathog
PubMed ID: 31730668
Doi: 10.1371/journal.ppat.1007687
Products & Services: Mutagenesis Services   
De novo design of potent and selective mimics of IL-2 and IL-15.
Authors: SilvaDaniel-Adriano，YuShawn，UlgeUmut Y，SpanglerJamie B，JudeKevin M，Lab?o-AlmeidaCarlos，AliLestat R，Quijano-RubioAlfredo，RuterbuschMikel，LeungIsabel，BiaryTamara，CrowleyStephanie J，MarcosEnrique，WalkeyCarl D，WeitznerBrian D，Pardo-AvilaFátima，CastellanosJavier，CarterLauren，StewartLance，RiddellStanley R，PepperMarion，BernardesGon?alo J L，DouganMichael，GarciaK Christopher，BakerD
Journal: Nature
PubMed ID: 30626941
Doi: 10.1038/s41586-018-0830-7
Products & Services: Mutagenesis Services   
PvdF of pyoverdin biosynthesis is a structurally unique N-formyltetrahydrofolate-dependent formyltransferase.
Authors: Kenji?Nikola，HoagMatthew R，MoraskiGarrett C，CaperelliCarol A，MoranGraham R，LambAudr
Journal: Arch. Biochem. Biophys.
PubMed ID: 30689984
Doi: 10.1016/j.abb.2019.01.028
Products & Services: Mutagenesis Services   
Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells.
Authors: PanHsuan-Yeh，AlamriAbdulla H，ValapalaMal
Journal: Cell. Mol. Biol. Lett.
PubMed ID: 31160892
Doi: 10.1186/s11658-019-0159-8
Products & Services: Mutagenesis Services   
Functional characterization of β-adrenergic and insulin receptor heteromers.
Authors: SusecMaja，SencanskiMilan，GlisicSanja，VeljkovicNevena，PedersenChristina，DrinovecLuka，StojanJurij，NøhrJane，VreclM
Journal: Neuropharmacology
PubMed ID: 30707913
Doi: 10.1016/j.neuropharm.2019.01.025
Products & Services: Mutagenesis Services   
Functional and structural analysis of rare SLC2A2 variants associated with Fanconi-Bickel syndrome and metabolic traits.
Authors: EnogieruOsatohanmwen J，UngPeter M U，YeeSook Wah，SchlessingerAvner，GiacominiKathle
Journal: Hum. Mutat.
PubMed ID: 30950137
Doi: 10.1002/humu.23758
Products & Services: Mammalian Expression System   Mutagenesis Services   
Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus.
Authors: ChoulesMary P，WolfNina M，LeeHyun，AndersonJeffrey R，GrzelakEdyta M，WangYuehong，MaRui，GaoWei，McAlpineJames B，JinYing-Yu，ChengJinhua，LeeHanki，SuhJoo-Won，DucNguyen Minh，PaikSeungwha，ChoeJin Ho，JoEun-Kyeong，ChangChulhun L，LeeJong Seok，JakiBirgit U，PauliGuido F，FranzblauScott G，ChoSang
Journal: Antimicrob. Agents Chemother.
PubMed ID: 30602512
Doi: 10.1128/AAC.02204-18
Products & Services: Mutagenesis Services   
Transient Expression in Islets During Pregnancy Correlates With β-Cell Survival， Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus.
Authors: Martin-MontalvoAlejandro，López-NoriegaLivia，Jiménez-MorenoCarmen，HerranzAmanda，LorenzoPetra I，Cobo-VuilleumierNadia，TamayoAlejandra，González-GuerreroCristian，HofsteedeJonathan S W R，LebretonFanny，BoscoDomenico，García ToscanoMiguel，HerranzLucrecia，AnselmoJoao，MorenoJosé Carlos，GauthierBeno
Journal: Diabetes
PubMed ID: 30352879
Doi: 10.2337/db18-0285
Products & Services: Mutagenesis Services   
Fat regulates expression of four-jointed reporters in vivo through a 20 bp element independently of the Hippo pathway.
Authors: ArbouzovaNatalia I，FulfordAlexander D，ZhangHongtao，McNeillH
Journal: Dev. Biol.
PubMed ID: 30858024
Doi: 10.1016/j.ydbio.2019.03.004
Products & Services: Mutagenesis Services   
Functional reclassification of variants of uncertain significance in the HCN4 gene identified in sudden unexpected death.
Authors: DongJingyun，SubbotinaEkaterina，WilliamsNori，SampsonBarbara A，TangYingying，CoetzeeWilli
Journal: Pacing Clin Electrophysiol
PubMed ID: 30578647
Doi: 10.1111/pace.13593
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