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TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation

Authors: Suyan Wang, Mengmeng Yu, Aijing Liu, Yuanling Bao, Xiaole Qi, Li Gao, Yuntong Chen, Peng Liu, Yulong Wang, Lixiao Xing, Lingzhai Meng, Yu Zhang, Linjin Fan, Xinyi Li, Qing Pan, Yanping Zhang, Hongyu Cui, Kai Li, Changjun Liu, Xijun He, Yulong Gao, Xiaomei Wang

Journal: PLoS Pathog

PubMed ID: 34516573

Doi: 10.1371/journal.ppat.1009900

Products & Services: Mutagenesis Services

CCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production

Authors: Nan Liang, Ming-Dong Yao, Ying Wang, Jia Liu, Lu Feng, Zhi-Ming Wang, Xiang-Yu Li, Wen-Hai Xiao, Ying-Jin Yuan

Journal: J Agric Food Chem

PubMed ID: 34554747

Doi: 10.1021/acs.jafc.1c04588

Products & Services: Mutagenesis Services

An ultra-sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma

Authors: Lei Liu, Hyunchang Kwak, Trebor L Lawton, Shan-Xue Jin, Angela L Meunier, Yifan Dang, Beth Ostaszewski, Alison C Pietras, Andrew M Stern, Dennis J Selkoe

Journal: Alzheimers Dement

PubMed ID: 34550630

Doi: 10.1002/alz.12457

Products & Services: Mutagenesis Services

Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation

Authors: Sarah M Glass, F Peter Guengerich

Journal: J Biol Chem

PubMed ID: 34480899

Doi: 10.1016/j.jbc.2021.101142

Products & Services: Mutagenesis Services

TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth

Authors: Tsz-Yin Chan, Christina M Egbert, Julia E Maxson, Adam Siddiqui, Logan J Larsen, Kristina Kohler, Eranga Roshan Balasooriya, Katie L Pennington, Tsz-Ming Tsang, Madison Frey, Erik J Soderblom, Huimin Geng, Markus Müschen, Tetyana V Forostyan, Savannah Free, Gaelle Mercenne, Courtney J Banks, Jonard Valdoz, Clifford J Whatcott, Jason M Foulks, David J Bearss, Thomas O'Hare, David C S Huang, Kenneth A Christensen, James Moody, Steven L Warner, Jeffrey W Tyner, Joshua L Andersen

Journal: Nat Commun

PubMed ID: 34504101

Doi: 10.1038/s41467-021-25622-3

Products & Services: Mutagenesis Services

Genetic and phenotypic heterogeneity in KIAA0753-related ciliopathies

Authors: Katherine A Inskeep, Yuri A Zarate, Danielle Monteil, Jurgen Spranger, Dan Doherty, Rolf W Stottmann, K Nicole Weaver

Journal: Am J Med Genet A

PubMed ID: 34523780

Doi: 10.1002/ajmg.a.62497

Products & Services: Mutagenesis Services

Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response

Authors: Kishu Ranjan, Matija Hedl, Saloni Sinha, Xuchen Zhang, Clara Abraham

Journal: J Clin Invest

PubMed ID: 34623328

Doi: 10.1172/JCI145472

Products & Services: Mutagenesis Services

Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity

Authors: Ashley C Dougherty, Mariam G Hawaz, Kristine G Hoang, Judy Trac, Jacob M Keck, Carmen Ayes, Joseph E Deweese

Journal: ACS Omega

PubMed ID: 34660952

Doi: 10.1021/acsomega.1c02083

Products & Services: Mutagenesis Services

The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA

Authors: Qian Huang, Bo Duan, Zhi Qu, Shilong Fan, Bin Xia

Journal: Molecules

PubMed ID: 34641320

Doi: 10.3390/molecules26195776

Products & Services: Mutagenesis Services

A Secreted Chorismate Mutase from pv Attenuates Virulence and Walnut Blight Symptoms

Authors: Renata de A B Assis, Cíntia H D Sagawa, Paulo A Zaini, Houston J Saxe, Phillip A Wilmarth, Brett S Phinney, Michelle Salemi, Leandro M Moreira, Abhaya M Dandekar

Journal: Int J Mol Sci

PubMed ID: 34638715

Doi: 10.3390/ijms221910374

Products & Services: Mutagenesis Services