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Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase.

Authors: WalesJessica A，ChenCheng-Yu，BreciLinda，WeichselAndrzej，BernierSylvie G，SheppeckJames E，SolingaRobert，NakaiTakashi，RenhowePaul A，JungJoon，MontfortWilli

Journal: J. Biol. Chem.

PubMed ID: 29222330

Doi: 10.1074/jbc.RA117.000457

Products & Services: PCR Cloning and Subcloning

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity.

Authors: SteinhardtJames J，GuenagaJavier，TurnerHannah L，McKeeKrisha，LouderMark K，O'DellSijy，ChiangChi-I，LeiLin，GalkinAndrey，AndrianovAlexander K，A Doria-RoseNicole，BailerRobert T，WardAndrew B，MascolaJohn R，LiYu

Journal: Nat Commun

PubMed ID: 29491415

Doi: 10.1038/s41467-018-03335-4

Products & Services: PCR Cloning and Subcloning

Antibodies towards Tyrosine Amyloid-Like Fibrils Allow Toxicity Modulation and Cellular Imaging of the Assemblies.

Authors: ZaguriDor，KreiserTopaz，Shaham-NivShira，Gazit

Journal: Molecules

PubMed ID: 29861432

Doi: 10.3390/molecules23061273

Products & Services: PCR Cloning and Subcloning

Caenorhabditis elegans BRICHOS Domain-Containing Protein C09F5.1 Maintains Thermotolerance and Decreases Cytotoxicity of Aβ by Activating the UPR.

Authors: SongMyungchul，SongKyunghee，KimSunghee，LeeJinyoung，HwangSueyun，HanChing

Journal: Genes (Basel)

PubMed ID: 29534049

Doi: 10.3390/genes9030160

Products & Services: PCR Cloning and Subcloning

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets.

Authors: Hobor Fruzsina，Dallmann Andre，Ball Neil J，Cicchini Carla，Battistelli Cecilia，Ogrodowicz Roksana W，Christodoulou Evangelos，Martin Stephen R，Castello Alfredo，Tripodi Marco，Taylor Ian A，Ramos An

Journal: Nat Commun

PubMed ID: 29483512

Doi: 10.1038/s41467-018-03182-3

Products & Services: PCR Cloning and Subcloning

The cereal pathogen Fusarium pseudograminearum produces a new class of active cytokinins during infection.

Authors: Sørensen Jens Laurids，Benfield Aurelie H，Wollenberg Rasmus Dam，Westphal Klaus，Wimmer Reinhard，Nielsen Mikkel Rank，Nielsen Kristian Fog，Carere Jason，Covarelli Lorenzo，Beccari Giovanni，Powell Jonathan，Yamashino Takafumi，Kogler Herbert，Sondergaard Teis Esben，Gardiner Donald

Journal: Mol. Plant Pathol.

PubMed ID: 28802024

Doi: 10.1111/mpp.12593

Products & Services: PCR Cloning and Subcloning

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.

Authors: EstornesYann，DondelingerYves，WeberKathrin，BruggemanInge，PeallAdam，MacFarlaneMarion，LebecqueSerge，VandenabeelePeter，BertrandMathieu

Journal: Cell Death Dis

PubMed ID: 29717117

Doi: 10.1038/s41419-018-0544-7

Products & Services: PCR Cloning and Subcloning

Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells.

Authors: Emami-ShahriNia，FosterJulie，KashaniRoxana，GazinskaPatrycja，CookCelia，SosabowskiJane，MaherJohn，PapaSo

Journal: Nat Commun

PubMed ID: 29540684

Doi: 10.1038/s41467-018-03524-1

Products & Services: PCR Cloning and Subcloning

SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate.

Authors: MatyskielaMary E，CoutoSuzana，ZhengXinde，LuGang，HuiJulia，StampKatie，DrewClifton，RenYan，WangMaria，CarpenterAaron，LeeChung-Wein，ClaytonThomas，FangWei，LuChin-Chun，RileyMariko，AbdubekPolat，BleaseKate，HartkeJames，KumarGondi，VesseyRupert，RolfeMark，HamannLawrence G，ChamberlainPhil

Journal: Nat. Chem. Biol.

PubMed ID: 30190590

Doi: 10.1038/s41589-018-0129-x

Products & Services: PCR Cloning and Subcloning

p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells.

Authors: IhryRobert J，WorringerKathleen A，SalickMax R，FriasElizabeth，HoDaniel，TheriaultKraig，KommineniSravya，ChenJulie，SondeyMarie，YeChaoyang，RandhawaRanjit，KulkarniTripti，YangZinger，McAllisterGregory，RussCarsten，Reece-HoyesJohn，ForresterWilliam，HoffmanGregory R，DolmetschRicardo，KaykasAja

Journal: Nat. Med.

PubMed ID: 29892062

Doi: 10.1038/s41591-018-0050-6

Products & Services: PCR Cloning and Subcloning