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Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses

Authors: Brendan T Freitas, Daniil A Ahiadorme, Rahul S Bagul, Ian A Durie, Samir Ghosh, Jarvis Hill, Naomi E Kramer, Jackelyn Murray, Brady M O'Boyle, Emmanuel Onobun, Michael G Pirrone, Justin D Shepard, Suzanne Enos, Yagya P Subedi, Kapil Upadhyaya, Ralph A Tripp, Brian S Cummings, David Crich, Scott D Pegan

Journal: ACS Infect Dis

PubMed ID: 35199517

Doi: 10.1021/acsinfecdis.1c00631

Products & Services: PCR Cloning and Subcloning

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

Authors: M Gordon Joyce, Hannah A D King, Ines Elakhal-Naouar, Aslaa Ahmed, Kristina K Peachman, Camila Macedo Cincotta, Caroline Subra, Rita E Chen, Paul V Thomas, Wei-Hung Chen, Rajeshwer S Sankhala, Agnes Hajduczki, Elizabeth J Martinez, Caroline E Peterson, William C Chang, Misook Choe, Clayton Smith, Parker J Lee, Jarrett A Headley, Mekdi G Taddese, Hanne A Elyard, Anthony Cook, Alexander Anderson, Kathryn McGuckin Wuertz, Ming Dong, Isabella Swafford, James Brett Case, Jeffrey R Currier, Kerri G Lal, Sebastian Molnar, Manoj S Nair, Vincent Dussupt, Sharon P Daye, Xiankun Zeng, Erica K Barkei, Hilary M Staples, Kendra Alfson, Ricardo Carrion, Shelly J Krebs, Dominic Paquin-Proulx, Nicos Karasavva, Victoria R Polonis, Linda L Jagodzinski, Mihret F Amare, Sandhya Vasan, Paul T Scott, Yaoxing Huang, David D Ho, Natalia de Val, Michael S Diamond, Mark G Lewis, Mangala Rao, Gary R Matyas, Gregory D Gromowski, Sheila A Peel, Nelson L Michael, Diane L Bolton, Kayvon Modjarrad

Journal: Sci Transl Med

PubMed ID: 34914540

Doi: 10.1126/scitranslmed.abi5735

Products & Services: PCR Cloning and Subcloning

The cell adhesion protein dystroglycan affects the structural remodeling of dendritic spines

Authors: Izabela Figiel, Ewa Bączyńska, Tomasz Wójtowicz, Marta Magnowska, Anna Buszka, Monika Bijata, Jakub Włodarczyk

Journal: Sci Rep

PubMed ID: 35169214

Doi: 10.1038/s41598-022-06462-7

Products & Services: PCR Cloning and Subcloning

Elicitation of potent SARS-CoV-2 neutralizing antibody responses through immunization with a versatile adenovirus-inspired multimerization platform

Authors: Christopher Chevillard, Axelle Amen, Solène Besson, Dalil Hannani, Isabelle Bally, Valentin Dettling, Evelyne Gout, Christophe J Moreau, Marlyse Buisson, Salomé Gallet, Daphna Fenel, Emilie Vassal-Stermann, Guy Schoehn, Pascal Poignard, Marie-Claire Dagher, Pascal Fender

Journal: Mol Ther

PubMed ID: 35151843

Doi: 10.1016/j.ymthe.2022.02.011

Products & Services: PCR Cloning and Subcloning

Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus

Authors: Sau Yee Tsoi, Merve Öncül, Ella Svahn, Mark Robertson, Zuzanna Bogdanowicz, Christina McClure, Gülşen Sürmeli

Journal: Elife

PubMed ID: 35188100

Doi: 10.7554/eLife.73162

Products & Services: PCR Cloning and Subcloning

Design of Synthetic Mammalian Promoters Using Highly Palindromic Subsequences

Authors: Polina Govorkova, Chee Ka Candice Lam, Kevin Truong

Journal: ACS Synth Biol

PubMed ID: 35225601

Doi: 10.1021/acssynbio.1c00600

Products & Services: PCR Cloning and Subcloning

Structure−Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels

Authors: Naglaa Salem El-Sayed, Young-Woo Nam, Polina A Egorova, Hai Minh Nguyen, Razan Orfali, Mohammad Asikur Rahman, Grace Yang, Heike Wulff, Ilya Bezprozvanny, Keykavous Parang, Miao Zhang

Journal: J Med Chem

PubMed ID: 34962403

Doi: doi/10.1021/acs.jmedchem.1c01473.

Products & Services: PCR Cloning and Subcloning

Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants

Authors: Taichi Kuramochi, Siok Wan Gan, Adrian W S Ho, Bei Wang, Nagisa Kageji, Takeru Nambu, Sayaka Iida, Momoko Okuda-Miura, Wei Shan Chia, Chiew Ying Yeo, Dan Chen, Wen-Hsin Lee, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Cheng-I Wang, Tomoyuki Igawa, Hideaki Shimada

Journal: MAbs

PubMed ID: 35293276

Doi: 10.1080/19420862.2022.2040350

Products & Services: PCR Cloning and Subcloning

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

Authors: Raffaele Iennaco, Giulio Formenti, Camilla Trovesi, Riccardo Lorenzo Rossi, Chiara Zuccato, Tiziana Lischetti, Vittoria Dickinson Bocchi, Andrea Scolz, Cristina Martínez-Labarga, Olga Rickards, Michela Pacifico, Angelica Crottini, Anders Pape Møller, Richard Zhenghuan Chen, Thomas Francis Vogt, Giulio Pavesi, David Stephen Horner, Nicola Saino, Elena Cattaneo

Journal: Cell Death Differ

PubMed ID: 34974533

Doi: 10.1038/s41418-021-00914-9

Products & Services: PCR Cloning and Subcloning

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Authors: Icaro Putinhon Caruso, Vitor Dos Santos Almeida, Mariana Juliani do Amaral, Guilherme Caldas de Andrade, Gabriela Rocha de Araújo, Talita Stelling de Araújo, Jéssica Moreira de Azevedo, Glauce Moreno Barbosa, Leonardo Bartkevihi, Peter Reis Bezerra, Katia Maria Dos Santos Cabral, Isabella Otênio de Lourenço, Clara L F Malizia-Motta, Aline de Luna Marques, Nathane Cunha Mebus-Antunes, Thais Cristtina Neves-Martins, Jéssica Maróstica de Sá, Karoline Sanches, Marcos Caique Santana-Silva, Ariana Azevedo Vasconcelos, Marcius da Silva Almeida, Gisele Cardoso de Amorim, Cristiane Dinis Anobom, Andrea T Da Poian, Francisco Gomes-Neto, Anderson S Pinheiro, Fabio C L Almeida

Journal: Int J Biol Macromol

PubMed ID: 35077748

Doi: 10.1016/j.ijbiomac.2022.01.121

Products & Services: PCR Cloning and Subcloning