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Heterologous synthesis of a simplified nitrogenase analog in Escherichia coli
Authors: Yiling A Liu, Chi Chung Lee, Kamil Górecki, Martin T Stiebritz, Calder Duffin, Joseph B Solomon, Markus W Ribbe, Yilin Hu
Journal: SCIENCE ADVANCES
PubMed ID: 40315313
Doi: 10.1126/sciadv.adw6785
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Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring
Authors: Xiangwei Wu, Huasong Ai, Junxiong Mao, Hongyi Cai, Lu-Jun Liang, Zebin Tong, Zhiheng Deng, Qingyun Zheng, Lei Liu, Man Pan
Journal: nature COMMUNICATION
PubMed ID: 40341121
Doi: doi.org/10.1038/s41467-025-59569-6
Identification of naturally occurring drug-resistant mutations of SARS-CoV-2 papain-like protease
Authors: Haozhou Tan, Qianru Zhang, Kyriakos Georgiou, Siyu Zhang, Kan Li, George Lambrinidis, Antonios Kolocouris, Xufang Deng, Jun Wang
Journal: Nature Communications
PubMed ID: 40379662
Doi: 10.1038/s41467-025-59922-9
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A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress
Authors: Suman Pokhrel, Gwangbeom Heo, Irimpan Mathews, Shun Yokoi, Tsutomu Matsui, Ayori Mitsutake, Soichi Wakatsuki, Daria Mochly-Rosen
Journal: Nature Communications
PubMed ID: 40328741
Doi: 10.1038/s41467-025-59434-6
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Fe(III)−H2O2 as an Alternative Oxidant for Catalytic Sulfoxidation in Cytochrome P450 Enzymes: Combined Theoretical and Experimental Evidence
Authors: Musen Li, Langxing Liao, Zhihui Jiang, Zongyu Bao, Shengbiao Ji, Binju Wang
Journal: ACS catalysis
Doi: doi.org/10.1021/acscatal.5c01673
Products & Services: Gene Synthesis   Codon Optimization   
Microtubules in Asgard archaea
Authors: Florian Wollweber, Jingwei Xu, Rafael I Ponce-Toledo, Florina Marxer, Thiago Rodrigues-Oliveira, Anja Pössnecker, Zhen-Hao Luo, Jessie James Limlingan Malit, Anastasiia Kokhanovska, Michal Wieczorek, Christa Schleper, Martin Pilhofer
Journal: Cell
PubMed ID: 40120574
Doi: 10.1016/j.cell.2025.02.027
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SARS-related coronavirus S-protein structures reveal synergistic RBM interactions underpinning high-affinity human ACE2 binding
Authors: Jingjing Wang, Yong Ma, Zimu Li, Hang Yuan, Banghui Liu, Zexuan Li, Mengzhen Su, Gul Habib, Yutong Liu, Lutang Fu, Peiyi Wang, Mei Li, Jun He, Jing Chen, Peng Zhou, Zhengli Shi, Xinwen Chen, Xiaoli Xiong
Journal: SCIENCE ADVANCES
PubMed ID: 40085715
Doi: 10.1126/sciadv.adr8772
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Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery
Authors: Jiaolong Wang, Rune T Kidmose, Niels Boegholm, Nevin K Zacharia, Mads B Thomsen, Anni Christensen, Tara Malik, Karl Lechtreck, Esben Lorentzen
Journal: The Journal of biological chemistry
PubMed ID: 39880089
Doi: 10.1016/j.jbc.2025.108237
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Structural basis of gap-filling DNA synthesis in the nucleosome by DNA Polymerase β
Authors: Tyler M Weaver, Benjamin J Ryan, Spencer H Thompson, Adil S Hussen, Jonah J Spencer, Zhen Xu, Nicholas J Schnicker, Bret D Freudenthal
Journal: Nature Communications
PubMed ID: 40097433
Doi: 10.1038/s41467-025-57915-2
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Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs
Authors: Jibin Cui , Qingyun Zheng , Yicheng Weng , Xiaoguo Zhai , Zhen Su , Yunxiang Du , Xiaoxiong Wei , Yuanyuan Yu , Qian Qu , Man Pan
Journal: Analytical Chemistry
PubMed ID: 40000409
Doi: doi.org/10.1002/anie.202501488
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