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The E3 ubiquitin ligase Cbl-b improves the prognosis of RANK positive breast cancer patients by inhibiting RANKL-induced cell migration and metastasis.

Authors: ZhangLingyun，TengYuee，FanYibo，WangYan，LiWei，ShiJing，MaYanju，LiCe，ShiXiaonan，QuXiujuan，LiuYun

Journal: Oncotarget

PubMed ID: 26087197

Doi: 10.18632/oncotarget.4382

Products & Services: Gene Synthesis

Juvenile Greenland sharks Somniosus microcephalus (Bloch & Schneider, 1801) in the Canadian Arctic

Authors: Nigel E. HusseyEmail authorAurelie Cosandey-GodinRyan P. WalterKevin J. HedgesMelanie VanGerwen-ToyneAmanda N. BarkleySteven T. KesselAaron T. Fisk

Journal: Polar Biology

Doi: 10.1007/s00300-014-1610-y

Products & Services: Gene Synthesis

Traditional and molecular detection methods reveal intense interguild competition and other multitrophic interactions associated with native entomopathogenic

Authors: Raquel Campos-HerreraEmail authorGeoffrey JaffuelXavier ChiribogaRubén Blanco-PérezMarie FesseletVladimír PůžaFabio MascherTed C. J. Turlings

Journal: Plant and Soil

Doi: 10.1007/s11104-014-2358-4

Products & Services: Gene Synthesis

Development of Pleurocidin-poly (vinyl alcohol) electrospun antimicrobial nanofibers to retain antimicrobial activity in food system application

Authors: Wang, Xiaoyuan, Yue, Tianli, Lee, Tung-ching

Journal: Food control 2015

Doi: 10.1016/j.foodcont.2015.02.001

Products & Services: Gene Synthesis

Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter， THTR-2 (SLC19A3).

Authors: LiangXiaomin，ChienHuan-Chieh，YeeSook Wah，GiacominiMarilyn M，ChenEugene C，PiaoMeiling，HaoJia，TwelvesJolyn，LepistEve-Irene，RayAdrian S，GiacominiKathle

Journal: Mol. Pharm.

PubMed ID: 26528626

Doi: 10.1021/acs.molpharmaceut.5b00501

Products & Services: Gene Synthesis

Recombinant expression, molecular characterization and crystal structure of antitumor enzyme, L-lysine α-oxidase from Trichoderma viride.

Authors: Amano M, Mizuguchi H, Sano T, Kondo H, Shinyashiki K, Inagaki J, Tamura T, Kawaguchi T, Kusakabe H, Imada K, Inagaki K.

Journal: J Biochem

PubMed ID: 25648943

Doi: 10.1093/jb/mvv012

Products & Services: Gene Synthesis

Amastin Knockdown in Leishmania braziliensis Affects Parasite-Macrophage Interaction and Results in Impaired Viability of Intracellular Amastigotes.

Authors: de Paiva RM, Grazielle-Silva V, Cardoso MS, Nakagaki BN, Mendonça-Neto RP, Canavaci AM, Souza Melo N, Martinelli PM, Fernandes AP, daRocha WD, Teixeira SM.

Journal: PLoS Pathog

PubMed ID: 26641088

Doi: 10.1371/journal.ppat.1005296

Products & Services: Gene Synthesis

C-terminal cleavage of human Foxp3 at a proprotein convertase motif abrogates its suppressive function.

Authors: Elhage R, Cheraï M, Levacher B, Darrasse-Jeze G, Baillou C, Zhao X, Khatib AM, Piaggio E, Klatzmann D.

Journal: Scand J Immunol

PubMed ID: 25683871

Doi: 10.1111/sji.12275

Products & Services: Gene Synthesis

Overexpression of the Large-Conductance, Ca2+-Activated K+ (BK) Channel Shortens Action Potential Duration in HL-1 Cardiomyocytes.

Authors: Stimers JR, Song L, Rusch NJ, Rhee SW.

Journal: PLoS ONE

PubMed ID: 26091273

Doi: 10.1371/journal.pone.0130588

Products & Services: Gene Synthesis

Discovery of type II inhibitors of TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2).

Authors: Tan L, Nomanbhoy T, Gurbani D, Patricelli M, Hunter J, Geng J, Herhaus L, Zhang J, Pauls E, Ham Y, Choi HG, Xie T, Deng X, Buhrlage SJ, Sim T, Cohen P, Sapkota G, Westover KD, Gray NS.

Journal: J Med Chem

PubMed ID: 25075558

Doi: 10.1021/jm500480k

Products & Services: Gene Synthesis