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The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo.

Authors: PowersNatalie R，ParvanovEmil D，BakerChristopher L，WalkerMichael，PetkovPetko M，PaigenKen

Journal: PLoS Genet.

PubMed ID: 27362481

Doi: 10.1371/journal.pgen.1006146

Products & Services: Gene Synthesis

Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening， Optimization， and Biological Evaluation.

Authors: XueXiaoqian，ZhangYan，LiuZhaoxuan，SongMing，XingYanli，XiangQiuping，WangZhen，TuZhengchao，ZhouYulai，DingKe，Xu

Journal: J. Med. Chem.

PubMed ID: 26731490

Doi: 10.1021/acs.jmedchem.5b01511

Products & Services: Gene Synthesis

Antisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3.

Authors: ToonenLodewijk J A，SchmidtIris，LuijsterburgMartijn S，van AttikumHaico，van Roon-MomWilleke

Journal: Sci Rep

PubMed ID: 27731380

Doi: 10.1038/srep35200

Products & Services: Gene Synthesis

Comparative Community Proteomics Demonstrates the Unexpected Importance of Actinobacterial Glycoside Hydrolase Family 12 Protein for Crystalline Cellulose Hydrolysis.

Authors: HirasJennifer，WuYu-Wei，DengKai，NicoraCarrie D，AldrichJoshua T，FreyDario，KolinkoSebastian，RobinsonErrol W，JacobsJon M，AdamsPaul D，NorthenTrent R，SimmonsBlake A，SingerStev

Journal: MBio

PubMed ID: 27555310

Doi: 10.1128/mBio.01106-16

Products & Services: Gene Synthesis

Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals.

Authors: MaesoIgnacio，DunwellThomas L，WyattChris D R，MarlétazFerdinand，VetőBorbála，BernalJuan A，QuahShan，IrimiaManuel，HollandPeter

Journal: BMC Biol.

PubMed ID: 27296695

Doi: 10.1186/s12915-016-0267-0

Products & Services: Gene Synthesis

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML.

Authors: HuangJu，LiuYuanfeng，AuBryan C，BarberDwayne L，ArrudaAndrea，SchambachAxel，RotheMichael，MindenMark D，PaigeChristopher J，MedinJeffr

Journal: Mol Ther Methods Clin Dev

PubMed ID: 27933304

Doi: 10.1038/mtm.2016.74

Products & Services: Gene Synthesis

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology.

Authors: TatzelKatharina，KurokiLindsay，DmitrievIgor，KashentsevaElena，CurielDavid T，GoedegebuureS Peter，PowellMatthew A，MutchDavid G，HawkinsWilliam G，Spitzer

Journal: Sci Rep

PubMed ID: 26935795

Doi: 10.1038/srep22661

Products & Services: Gene Synthesis

Structure-function analysis of myomaker domains required for myoblast fusion.

Authors: MillayDouglas P，GamageDilani G，QuinnMalgorzata E，MinYi-Li，MitaniYasuyuki，Bassel-DubyRhonda，OlsonEr

Journal: Proc. Natl. Acad. Sci. U.S.A.

PubMed ID: 26858401

Doi: 10.1073/pnas.1600101113

Products & Services: Gene Synthesis

Expanding Biosensing Abilities through Computer-Aided Design of Metabolic Pathways.

Authors: LibisVincent，DelépineBaudoin，FaulonJean-

Journal: ACS Synth Biol

PubMed ID: 27028723

Doi: 10.1021/acssynbio.5b00225

Products & Services: Gene Synthesis

Characterization of a novel DNA glycosylase from S. sahachiroi involved in the reduction and repair of azinomycin B induced DNA damage.

Authors: WangShan，LiuKai，XiaoLe，YangLiYuan，LiHong，ZhangFeiXue，LeiLei，LiShengQing，FengXu，LiAiYing，He

Journal: Nucleic Acids Res.

PubMed ID: 26400161

Doi: 10.1093/nar/gkv949

Products & Services: Gene Synthesis