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Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals.

Authors: BarbieriChristopher M，WangXinkang，WuWeizhen，ZhouXueping，OgawaAimie M，O'NeillKim，ChuDonald，CastriotaGino，SeiffertDietmar A，GutsteinDavid E，Che

Journal: J. Pharmacol. Exp. Ther.

PubMed ID: 28035006

Doi: 10.1124/jpet.116.238493

Products & Services: Gene Synthesis

Fluoromodules Consisting of a Promiscuous RNA Aptamer and Red or Blue Fluorogenic Cyanine Dyes: Selection， Characterization， and Bioimaging.

Authors: TanXiaohong，ConstantinTudor P，SloaneKelly L，WaggonerAlan S，BruchezMarcel P，ArmitageBru

Journal: J. Am. Chem. Soc.

PubMed ID: 28644615

Doi: 10.1021/jacs.7b04211

Products & Services: Gene Synthesis

Identification and characterization of a novel botulinum neurotoxin.

Authors: ZhangSicai，MasuyerGeoffrey，ZhangJie，ShenYi，LundinDaniel，HenrikssonLinda，MiyashitaShin-Ichiro，Martínez-CarranzaMarkel，DongMin，Stenmark

Journal: Nat Commun

PubMed ID: 28770820

Doi: 10.1038/ncomms14130

Products & Services: Gene Synthesis

Comparative analysis of chimeric ZFP-， TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells.

Authors: LuoWentian，GalvanDaniel L，WoodardLauren E，DorsetDan，LevyShawn，WilsonMatth

Journal: Nucleic Acids Res.

PubMed ID: 28666380

Doi: 10.1093/nar/gkx572

Products & Services: Gene Synthesis

Homozygous EEF1A2 mutation causes dilated cardiomyopathy， failure to thrive， global developmental delay， epilepsy and early death.

Authors: CaoSiqi，SmithLaura L，Padilla-LopezSergio R，GuidaBrandon S，BlumeElizabeth，ShiJiahai，MortonSarah U，BrownsteinCatherine A，BeggsAlan H，KruerMichael C，AgrawalPank

Journal: Hum. Mol. Genet.

PubMed ID: 28911200

Doi: 10.1093/hmg/ddx239

Products & Services: Gene Synthesis

Klotho restoration via acetylation of Peroxisome Proliferation-Activated Receptor γ reduces the progression of chronic kidney disease.

Authors: LinWenjun，ZhangQin，LiuLin，YinShasha，LiuZhihong，CaoWan

Journal: Kidney Int.

PubMed ID: 28416226

Doi: 10.1016/j.kint.2017.02.023

Products & Services: Gene Synthesis

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

Authors: KulpDaniel W，SteichenJon M，PauthnerMatthias，HuXiaozhen，SchiffnerTorben，LiguoriAlessia，CottrellChristopher A，Havenar-DaughtonColin，OzorowskiGabriel，GeorgesonErik，KalyuzhniyOleksandr，WillisJordan R，KubitzMichael，AdachiYumiko，ReissSamantha M，ShinMia，de ValNatalia，WardAndrew B，CrottyShane，BurtonDennis R，SchiefWilli

Journal: Nat Commun

PubMed ID: 29162799

Doi: 10.1038/s41467-017-01549-6

Products & Services: Gene Synthesis

Electronic control of gene expression and cell behaviour in Escherichia coli through redox signalling.

Authors: TschirhartTanya，KimEunkyoung，McKayRyan，UedaHana，WuHsuan-Chen，PottashAlex Eli，ZargarAmin，NegreteAlejandro，ShiloachJoseph，PayneGregory F，BentleyWilli

Journal: Nat Commun

PubMed ID: 28094788

Doi: 10.1038/ncomms14030

Products & Services: Gene Synthesis

Glutamate Deregulation in Ketamine-Induced Psychosis-A Potential Role of PSD95， NMDA Receptor and PMCA Interaction.

Authors: LisekMalwina，FerencBozena，StudzianMaciej，PulaskiLukasz，GuoFeng，ZylinskaLudmila，BoczekTo

Journal: Front Cell Neurosci

PubMed ID: 28701926

Doi: 10.3389/fncel.2017.00181

Products & Services: Gene Synthesis

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.

Authors: Kitevski-LeBlancJulianne，Fradet-TurcotteAmélie，KukicPredrag，WilsonMarcus D，PortellaGuillem，YuwenTairan，PanierStephanie，DuanShili，CannyMarella D，van IngenHugo，ArrowsmithCheryl H，RubinsteinJohn L，VendruscoloMichele，DurocherDaniel，KayLew

Journal: Elife

PubMed ID: 28406400

Doi: 10.7554/eLife.23872

Products & Services: Gene Synthesis