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Arabidopsis thaliana FLA4 functions as a glycan-stabilized soluble factor via its carboxy-proximal Fasciclin 1 domain.

Authors: Xue H, Veit C, Abas L, Tryfona T, Maresch D, Ricardi MM, Estevez JM,, Strasser R, Seifert GJ.

Journal: Plant J

PubMed ID: 28482115

Doi: 10.1111/tpj.13591

Products & Services: Gene Synthesis

A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo.

Authors: Shih TC, Liu R, Fung G, Bhardwaj G, Ghosh PM,,, Lam KS.

Journal: Mol Cancer Ther

PubMed ID: 28396365

Doi: 10.1158/1535-7163.MCT-16-0690

Products & Services: Gene Synthesis

Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia.

Authors: D'Souza A, Pearman CM, Wang Y, Nakao S, Logantha SJRJ, Cox C, Bennett H, Zhang Y, Johnsen AB, Linscheid N, Poulsen PC, Elliott J, Coulson J, McPhee J, Robertson A, da Costa Martins PA, Kitmitto A, Wisløff U, Cartwright EJ, Monfredi O, Lundby A, Dobrzynski H, Oceandy D, Morris GM, Boyett MR.

Journal: Circ Res

PubMed ID: 28821541

Doi: 10.1161/CIRCRESAHA.117.311607

Products & Services: Gene Synthesis

Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes.

Authors: LuChunfeng，XuWenxuan，ShaoJiangjuan，ZhangFeng，ChenAnping，ZhengShiz

Journal: Toxicol. Sci.

PubMed ID: 27837167

Doi: 10.1093/toxsci/kfw228

Products & Services: Gene Synthesis

An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses.

Authors: Holthausen DJ, Lee SH, Kumar VT, Bouvier NM, Krammer F, Ellebedy AH, Wrammert J, Lowen AC, George S, Pillai MR, Jacob J.

Journal: Immunity

PubMed ID: 28423338

Products & Services: Gene Synthesis

The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2.

Authors: Vető B,, Bojcsuk D, Bacquet C, Kiss J, Sipeki S, Martin L, Buday L,, Bálint BL, Arányi T,.

Journal: PLoS ONE

PubMed ID: 28196117

Doi: 10.1371/journal.pone.0172020

Products & Services: Gene Synthesis

Gene Delivery of Activated Factor VII Using Alternative Adeno-Associated Virus Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and Adeno-Associated Virus Neutralizing Antibodies.

Authors: Sun J,, Hua B,, Chen X, Samulski RJ,, Li C,.

Journal: Hum Gene Ther

PubMed ID: 28478688

Doi: 10.1089/hum.2017.016

Products & Services: Gene Synthesis

TUFT1, a novel candidate gene for metatarsophalangeal osteoarthritis, plays a role in chondrogenesis on a calcium-related pathway.

Authors: Sliz E,,, Taipale M,,, Welling M,,, Skarp S,,, Alaraudanjoki V, Ignatius J, Ruddock L,, Nissi R, Männikkö M,.

Journal: PLoS ONE

PubMed ID: 28410428

Doi: 10.1371/journal.pone.0175474

Products & Services: Gene Synthesis

Novel AgoshRNA molecules for silencing of the CCR5 co-receptor for HIV-1 infection.

Authors: Herrera-Carrillo E, Berkhout B.

Journal: PLoS ONE

PubMed ID: 28542329

Doi: 10.1371/journal.pone.0177935

Products & Services: Gene Synthesis

Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.

Authors: Merkel PA, Xie G, Monach PA, Ji X, Ciavatta DJ, Byun J, Pinder BD, Zhao A, Zhang J, Tadesse Y, Qian D, Weirauch M, Nair R, Tsoi A, Pagnoux C, Carette S, Chung S, Cuthbertson D, Davis JC Jr, Dellaripa PF, Forbess L, Gewurz-Singer O, Hoffman GS, Khalidi N, Koening C, Langford CA, Mahr AD, McAlear C, Moreland L, Seo EP, Specks U, Spiera RF, Sreih A, St Clair EW, Stone JH, Ytterberg SR, Elder JT, Qu J, Ochi T, Hirano N, Edberg JC, Falk RJ, Amos CI, Siminovitch KA; Vasculitis Clinical Research Consortium.

Journal: Arthritis Rheumatol

PubMed ID: 28029757

Doi: 10.1002/art.40034

Products & Services: Gene Synthesis