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Discovery of stimulation-responsive immune enhancers with CRISPR activation

Authors: SimeonovDimitre R, GowenBenjamin G, BoontanrartMandy, RothTheodore L, GagnonJohn D, MumbachMaxwell R, SatpathyAnsuman T, LeeYoujin, BrayNicolas L, ChanAlice Y, LituievDmytro S, NguyenMichelle L, GateRachel E, SubramaniamMeena, LiZhongmei, WooJonathan M, MitrosTherese, RayGraham J, CurieGemma L, NaddafNicki, ChuJulia S, MaHong, BoyerEric, Van GoolFrederic, HuangHailiang, LiuRuize, TobinVictoria R, SchumannKathrin, DalyMark J, FarhKyle K, AnselK Mark, YeChun J, GreenleafWilliam J, AndersonMark S, BluestoneJeffrey A, ChangHoward Y, CornJacob E, MarsonAlexa

Journal: Nature

PubMed ID: 28854172

Doi: 10.1038/nature23875

Products & Services: Gene Synthesis

Resveratrol Ameliorates Dysregulation of Th1， Th2， Th17， and T Regulatory Cell-Related Transcription Factor Signaling in a BTBR T + tf/J Mouse Model of Autism

Authors: BakheetSaleh A, AlzahraniMohammad Zeed, AnsariMushtaq Ahmad, NadeemAhmed, ZoheirKhairy M A, AttiaSabry M, Al-AyadhiLaila Yousef, AhmadSheikh F

Journal: Mol. Neurobiol.

PubMed ID: 27578011

Doi: 10.1007/s12035-016-0066-1

Products & Services: Gene Synthesis

Downregulation of lncRNA MEG3 and miR-770-5p inhibit cell migration and proliferation in Hirschsprung's disease.

Authors: LiHongxing, LiBo, ZhuDongmei, XieHua, DuChunxia, XiaYankai, TangWei

Journal: Oncotarget

PubMed ID: 29050236

Doi: 10.18632/oncotarget.19207

Products & Services: Gene Synthesis

Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice

Authors: Toonen LJA, Rigo F, van Attikum H, van Roon-Mom WMC

Journal: Molecular therapy. Nucleic acids

PubMed ID: 28918024

Doi: 10.1016/j.omtn.2017.06.019

Products & Services: Gene Synthesis

Synthesis and Evaluation of 1,2,4-Triazolo[1,5- a ]pyrimidines as Antibacterial Agents Against Enterococcus faecium

Authors: Huan Wang; Mijoon Lee; Zhihong Peng; Blas Bl zquez; Elena Lastochkin; Malika Kumarasiri; Renee Bouley; Mayland Chang; Shahriar Mobashery

Journal: Journal of Medicinal Chemistry

PubMed ID: 25923368

Doi: 10.1021/jm501831g

Products & Services: Gene Synthesis

Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3.

Authors: Maina PK, Shao P, Jia X, Liu Q, Umesalma S, Marin M, Long D Jr, Concepción-Román S, Qi HH.

Journal: Biochim Biophys Acta.

PubMed ID: 28734980

Products & Services: Gene Synthesis

Method for Multiplexing CRISPR/Cas9 in Using Artificial Target DNA Sequences

Authors: GierschRachael M, FinniganGrego

Journal: Bio Protoc

PubMed ID: 29082289

Doi: 10.21769/BioProtoc.2557

Products & Services: Gene Synthesis

Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes

Authors: KaustioMeri, HaapaniemiEmma, GöösHelka, HautalaTimo, ParkGiljun, SyrjänenJaana, EinarsdottirElisabet, SahuBiswajyoti, KilpinenSanna, RouniojaSamuli, FogartyChristopher L, GlumoffVirpi, KulmalaPetri, KatayamaShintaro, TameneFitsum, TrottaLuca, MorgunovaEkaterina, KrjutškovKaarel, NurmiKatariina, EklundKari, LagerstedtAnssi, HelminenMerja, MarteliusTimi, MustjokiSatu, TaipaleJussi, SaarelaJanna, KereJuha, VarjosaloMarkku, SeppänenM

Journal: J. Allergy Clin. Immunol.

PubMed ID: 28115215

Doi: 10.1016/j.jaci.2016.10.054

Products & Services: Gene Synthesis

Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects.

Authors: Ruben Shrestha,Gaochao Huang,David A.Meekins,Brian V.Geisbrecht,Ping Li.

Journal: ACS Catal.

Products & Services: Gene Synthesis

Long noncoding RNA MALAT-1 is a novel inflammatory regulator in human systemic lupus erythematosus.

Authors: YangHuaxia, LiangNaixin, WangMin, FeiYunyun, SunJian, LiZhiyuan, XuYuan, GuoChao, CaoZhili, LiShanqing, JiaoYu

Journal: Oncotarget

PubMed ID: 29100395

Doi: 10.18632/oncotarget.20490

Products & Services: Gene Synthesis