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页码: 46/793 每页显示数量

Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry

Authors: Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke Guddat, Hongli Chen, Leike Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang

Journal: Nat Commun

PubMed ID: 37990007

Doi: 10.1038/s41467-023-42527-5

Products & Services: Gene Synthesis

Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region

Authors: Qinhong Luo , Yue Ma , Huiting Liang , Yuan Feng , Na Liu, Chenshan Lian , Lizhi Zhu , Yuxin Ye , Zhihong Liu , Zhanfeng Hou , Sijin Chen , Yaqi Wang , Chuan Dai , Chunli Song , Min Zhang , Zhipeng He , Yun Xing , Wanjin Zhong , Shuiming Li , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li

Journal: J Med Chem .

PubMed ID: 37922441

Doi: 10.1021/acs.jmedchem.3c01549

Products & Services: Gene Synthesis

Dynamics of Serum-Neutralizing Antibody Responses in Vaccinees through Multiple Doses of the BNT162b2 Vaccine

Authors: Jared Sheehan, Caleb M Ardizzone, Mayank Khanna, Amber J Trauth, Michael E Hagensee, Alistair J Ramsay

Journal: Vaccines (Basel)

PubMed ID: 38006052

Doi: 10.3390/vaccines11111720

Products & Services: Gene Synthesis

Molecular Analysis of a Congenital Myasthenic Syndrome Due to a Pathogenic Variant Affecting the C-Terminus of ColQ

Authors: Susie Barbeau, Fannie Semprez, Alexandre Dobbertin, Laurine Merriadec, Florine Roussange, Bruno Eymard, Damien Sternberg, Emmanuel Fournier, Hanice Karasoy, Cécile Martinat, Claire Legay

Journal: Int J Mol Sci

PubMed ID: 38003406

Doi: 10.3390/ijms242216217

Products & Services: Gene Synthesis

A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice

Authors: Xuetao Yang , Xidan Yang , Shouwen Du , Congxia Hu , Xiu Yang , Xingyun Wang , Xing Hu , Nino Rcheulishvili , Peng George Wang and Jihui Lin

Journal: Vaccines.

Doi: 10.3390/vaccines11091420

Products & Services: Gene Synthesis

Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing

Authors: Segewkal Heruye, Jered Myslinski, Chao Zeng, Amy Zollman, Shinichi Makino, Azuma Nanamatsu, Quoseena Mir, Sarath Chandra Janga, Emma H Doud, Michael T Eadon, Bernhard Maier, Michiaki Hamada, Tuan M Tran, Pierre C Dagher, Takashi Hato

Journal: biorxiv

PubMed ID: 37986799

Doi: 10.1101/2023.11.09.566426

Products & Services: Gene Synthesis

Human mesenchymal stem cells derived from adipose tissue showed a more robust effect than those from the umbilical cord in promoting corneal graft survival by suppressing lymphangiogenesis

Authors: Huanmin Kang, Jianing Feng, Yingqian Peng, Yingyi Liu, Yalei Yang, Ying Wu, Jian Huang, Ying Jie, Baihua Chen, Yan He

Journal: Stem Cell Res Ther

PubMed ID: 37957770

Doi: 10.1186/s13287-023-03559-2

Products & Services: Gene Synthesis

Self−Assembling Nanovaccine Fused with Flagellin Enhances Protective Effect against Foot−and−Mouth Disease Virus

Authors: Chenchen Pei , Hu Dong , Zhidong Teng , Sumin Wei , Yun Zhang , Shuanghui Yin , Jianli Tang , Shiqi Sun and Huichen Guo

Journal: Vaccines

Doi: 10.3390/vaccines11111675

Products & Services: Gene Synthesis

SUMOylation-triggered ALIX activation modulates extracellular vesicles circTLCD4-RWDD3 to promote lymphatic metastasis of non-small cell lung cancer

Authors: Xiayao Diao, Chao Guo, Hanhao Zheng, Ke Zhao, Yuming Luo, Mingjie An, Yan Lin, Jiancheng Chen, Yuanlong Li, Yuting Li, Xuehan Gao, Jiaqi Zhang, Mengxin Zhou, Wenliang Bai, Lei Liu, Guige Wang, Lanjun Zhang, Xiaotian He, Rusi Zhang, Zhihua Li, Changhao Chen, Shanqing Li

Journal: Signal Transduct Target Ther

PubMed ID: 37925421

Doi: 10.1038/s41392-023-01685-0

Products & Services: Gene Synthesis

The sleep quality- and myopia-linked PDE11A-Y727C variant impacts neural physiology by reducing catalytic activity and altering subcellular compartmentalization of the enzyme

Authors: Irina Sbornova, Emilie van der Sande, Snezana Milosavljevic, Elvis Amurrio, Steven D Burbano, Prosun Das, Helen Do, Janet L Fisher, Porschderek Kargbo, Janvi Patel, Latarsha Porcher, Chris I De Zeeuw, Magda A Meester-Smoor, Beerend H J Winkelman, Caroline C W Klaver, Ana Pocivavsek, Michy P Kelly

Journal: biorxiv

PubMed ID: 38014312

Doi: 10.1101/2023.11.16.567422

Products & Services: Gene Synthesis