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Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing

Authors: Qiubing Chen, Xuebin Wang, Yizhou Zhang, Ming Tian, Junyi Duan, Ying Zhang, Hao Yin

Journal: NSR

Doi: 10.1093/nsr/nwae135

Products & Services: Gene Synthesis

Visualization of the Association of Dimeric Protein Complexes on Specific Enhancers in the Salivary Gland Nuclei of Larva

Authors: Solène Vanderperre, Samir Merabet

Journal: Cells

PubMed ID: 38607052

Doi: 10.3390/cells13070613

Products & Services: Gene Synthesis

The molecular immune modulator adenosine deaminase-1 enhances HIV specific humoral and cellular responses to a native-like HIV envelope trimer DNA vaccine

Authors: Michele A Kutzler, Gina Cusimano, David Joyner, Emily Konopka, Roshell Muir, Philip Barnette, Melanie Guderian, Iván Del Moral-Sánchez, Ronald Derking, Tom Bijl, Jonne Snitselaar, Photis Rotsides, Kyra Woloszczuk, Matthew Bell, Gabriela Canziani, Irwin Chaiken, Ann Hessell, Yannic Bartsch, Rogier Sanders, Elias Haddad

Journal: Res Sq

PubMed ID: 38746176

Doi: 10.21203/rs.3.rs-4139764/v1

Products & Services: Gene Synthesis

Mitochondria-Selective Dicationic Small-Molecule Ligand Targeting G-Quadruplex Structures for Human Colorectal Cancer Therapy

Authors: Bo-Xin Zheng, Wei Long, Wende Zheng, Yaoxun Zeng, Xiao-Chun Guo, Ka-Hin Chan, Meng-Ting She, Alan Siu-Lun Leung, Yu-Jing Lu, Wing-Leung Wong

Journal: J Med Chem

PubMed ID: 38624086

Doi: 10.1021/acs.jmedchem.3c02240

Products & Services: Gene Synthesis

Developing a Novel Enzalutamide-Resistant Prostate Cancer Model via AR F877L Mutation in LNCaP Cells

Authors: Ruifeng Wang, Shuhua Ma, Nengwei Xu, Yumiao Gan, Pengya Li, Jingying Zhang, Zhixiang Zhang, Qingyang Gu, Jian Xiang

Journal: Curr Protoc

PubMed ID: 38652202

Doi: 10.1002/cpz1.1033

Products & Services: Gene Synthesis

Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system

Authors: Lijie Guo, Pingping Huang, Zhaoxing Li, Young-Cheul Shin, Purui Yan, Meiling Lu, Meirong Chen, Yibei Xiao

Journal: Nat Chem Biol

PubMed ID: 37932527

Doi: 10.1038/s41589-023-01478-0

Products & Services: Molecular Biology Reagents Gene Synthesis

A selective Fibroblast Growth Factor Receptor 1/2 PROTAC degrader with 1 antitumor activity

Authors: Ying Kong , Xinyue Zhao , Zhaofu Wang , Siqi Yuan , Sheng Chen , Shidi Lou , Shichao Ma , Yunfeng Li , Xinghao Wang , Yangfeng Ge , Guobin Li , Hongbing Yang , Mengxi Zhao , Dandan Li , Hailong Zhang , Wenfu Tan , Juan Wang

Journal: Molecular cancer therapeutics

PubMed ID: 38647531

Doi: 10.1158/1535-7163.MCT-23-0719

Products & Services: Gene Synthesis

Identification of hyperthermophilic D-allulose 3-epimerase from Thermotoga sp and its application as a high-performance biocatalyst for D-allulose synthesis

Authors: Ji-Dong Shen, Bao-Ping Xu, Te-Li Yu, Yong-Xiang Fei, Xue Cai, Liang-Gang Huang, Li-Qun Jin, Zhi-Qiang Liu, Yu-Guo Zheng

Journal: Bioprocess Biosyst Eng

PubMed ID: 38676737

Doi: 10.1007/s00449-024-02989-3

Products & Services: Gene Synthesis

The Female-Biased General Odorant Binding Protein 2 of Displays Binding Affinity for Biologically Active Host Plant Volatiles

Authors: Jingjing Tu, Zehua Wang, Fan Yang, Han Liu, Guanghang Qiao, Aihuan Zhang, Shanning Wang

Journal: Biology (Basel)

PubMed ID: 38666886

Doi: 10.3390/biology13040274

Products & Services: Gene Synthesis

AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans

Authors: Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran

Journal: Science immunology

PubMed ID: 38579013

Doi: 10.1126/sciimmunol.adi8039

Products & Services: Gene Synthesis