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N-Acetylcysteine–Mediated Surface Remodeling of Inhaled mRNA Lipid Nanoparticles Enables Coordinated Mucosal and Systemic Antitumor Immunity

Authors: Xingdi Cheng, Qing Li, Haowei Zu, Shuai Liu, Jingjiao Li, Yixing Wen, Chen Yang, Simin Sun, Haoyu Lu, Yuzhou Zhang, Yumeng Zhao, Guizhi Shi, Meng Qin, Xueguang Lu

Journal: ADVANCED MATERIALS

PubMed ID: 42124519

Doi: doi.org/10.1002/adma.73362

Products & Services: Gene Synthesis

Deciphering the Mechanism: Overcoming Incompatibility for Continuous Cap‑1 mRNA Synthesis via Multienzyme Cascades

Authors: Shiyi Che, , Zhengjun Li, Zhiguo Su, Aibing Yu, Minsu Liu, and Songping Zhang

Journal: ACS Sustainable Chemistry & Engineering

Doi: 10.1021/acssuschemeng.5c12019

Products & Services: Gene Synthesis

Regulated transformation system (RTS): sddi-mediated programmable shut-off and mode switching of base editors

Authors: Jiacheng Deng, Jian Zhou, Hongyong Xiang, Xueyuan Li, Xiang Han, Zhen Weng, Junbo Jia, Yingshuo Shao, Yang Sima, Ming Niu, Dongmeng Li, Hongsheng Ouyang, Bin Xu, Daxin Pang, Lin Yang, Hongming Yuan

Journal: Nucleic Acids Research

PubMed ID: 41909950

Doi: doi.org/10.1093/nar/gkag162

Products & Services: Gene Synthesis Codon Optimization

From Field Overexpression to Biochemical Function: PxCYP6B4 Mediated Hydroxylation Confers Pyrethroid Resistance in Plutella xylostella

Authors: Zhuoda Liu, Yifei Zhou, Dongliang Wang, Ruichi Li, Zhen Tian, Yifan Li, Jiyuan Liu

Journal: Journal of Agricultural and Food Chemistry

PubMed ID: 41645610

Doi: 10.1021/acs.jafc.6c00843

Products & Services: Gene Synthesis Codon Optimization

Genome-Wide Identification, Characterization, Expression Analysis, and Interacting Protein Prediction of the GSK3/Shaggy-like Gene Family in Watermelon

Authors: Peng Tian, Jingjing Zhang, Bowen Liu, Xiurui Gao, Bing Li, Wei Liu and Yanrong Wu

Journal: Plants-Basel

Doi: 10.3390/plants15030484

Products & Services: Gene Synthesis

Nanobody-Based Bioconjugates as Potent and Broadly Active Inhibitors of HIV Entry

Authors: Shubhra Jyoti Saha, Rashmi Kumariya, Phoenix A Davis, Emily Tourtellott, Nicole Doria-Rose, Carole A Bewley, Ross W Cheloha

Journal: Journal of the American Chemical Society

PubMed ID: 41592176

Doi: 10.1021/jacs.5c22670

Products & Services: Gene Synthesis

Quantitative genetics of natural S. cerevisiae strains upon mating reveal heritable determinants of fitness and differential mating affinities

Authors: Sivan Kaminski Strauss, Ruthie Golomb, Donya Khoury, Noa Aharon-Hefetz, Hadar Meyer, Dayag Sheykhkarimli, Gianni Liti, Orna Dahan, Yitzhak Pilpel

Journal: Molecular Therapy

PubMed ID: 41689801

Doi: 10.1016/j.celrep.2026.116972

Products & Services: Gene Synthesis

Heterologous vs. homologous vaccine regimens: Sulfated lactosyl archaeol (SLA) archaeosome-adjuvanted SARS-CoV-2 spike protein boost following an mRNA/LNP prime induces robust and balanced immune responses

Authors: Tyler M Renner, Gerard Agbayani, Hiva Azizi, Lise Deschatelets, Renu Dudani, Blair A Harrison, Usha D Hemraz, Roger Koukiekolo, Matthew Stuible, Yves Durocher, Michael J McCluskie, Bassel Akache

Journal: Vaccine

PubMed ID: 41505874

Doi: 10.1016/j.vaccine.2025.128182

Products & Services: Codon Optimization Gene Synthesis

High-yield production of hydroxytyrosol through metabolic engineering of Yarrowia lipolytica

Authors: Bihuan Chen, Yuanyuan Wang, Danlin Wang, Yina Wang, Xiangyu Liu, Guanghui Zhang, Shengchao Yang

Journal: Synthetic and systems biotechnology

PubMed ID: 41766957

Doi: 10.1016/j.synbio.2026.01.022

Products & Services: Gene Synthesis Codon Optimization

Genome position does not impact transgene expression efficiency in the ancient red alga Cyanidioschyzon merolae

Authors: Kaian Teles, Gordon B Wellman, Yuhan Zhang, Bárbara Bastos de Freitas, Viktor A Slat, Martha R Stark, Lecong Zhou, Perry J Blackshear, Stephen D Rader, Kyle J Lauersen

Journal: bioRXIV

PubMed ID: 41659391

Doi: 10.1016/j.nbt.2026.05.004

Products & Services: Gene Synthesis