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Thermodynamic Profiling Reveals DNA Polymerase Template Binding, Substrate Incorporation, and Exonuclease Function

Authors: Yaping Sun, Wu Lin, Kang Fu, Jie Gao, Xianhui Zhao, Yun He, Hui Tian

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms262411909

Products & Services: Gene Synthesis Plasmid DNA Preparation Protein Electrophoresis and Western CRISPR KI Templates

Iterative Epitope Expansion Enables Structure-Guided de novo Design of IgE-Binding Miniproteins Targeting the FcεRI Interface

Authors: Ido Calman, Hamed Shaykhalishahi, Puwanat Sangkhapreecha, Sharrol Bachas

Journal: biorxiv

Doi: 10.64898/2025.12.27.696647

Products & Services: Protein portfolio

Gut Microbe-Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Authors: Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao

Journal: Advanced Science

PubMed ID: 41386783

Doi: 10.1002/advs.202520326

Products & Services: Protein Electrophoresis and Western

Molecular insights into ligand recognition and signaling of OXGR1

Authors: Aijun Liu, Yezhou Liu, Yuanzhengyang Long, Richard D Ye

Journal: Nature Communications

PubMed ID: 41413034

Doi: 10.1038/s41467-025-67101-z

Products & Services: Protein and Antibody Isolation

Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Protein and Antibody Isolation

Semi-inductive dataset construction and framework optimization for practical drug target interaction prediction with ScopeDTI

Authors: Yigang Chen; Xiang Ji; Ziyue Zhang; Zihao Zhu; Yuming Zhou; Chang Su; Yang-Chi-Dung Lin; Hsi-Yuan Huang; Kangping Wei; Yi Lai; Ke Chen; Xingqiao Lin; Yangyi Zhang; Jiehui Fu; Yixian Huang; Shidong Cui; Shih-Chung Yen; Tao Zhang; Arieh Warshel; Hsien-Da Huang

Journal: Nature Communications

PubMed ID: 41390462

Doi: 10.1038/s41467-025-66311-9

Products & Services: Protein Electrophoresis and Western

Synthesis of Bispecific Conjugates by ADP-Ribosyl Cyclases

Authors: Sunny H Kim, Arshad J Ansari, Lei Zhang, Guoyun Kao, Thuc Oanh Hoang, Zeyu Zhang, Srinivasarao Singireddi, Benjamin B Katz, Yong Zhang

Journal: Advanced Science

PubMed ID: 41422434

Doi: 10.1002/advs.202518329

Products & Services: Protein and Antibody Isolation

Supramolecular lipid nanoparticle reprograms tumor microenvironment by cucurbit[7]uril-based host–guest recognition for STING-activating cancer immunotherapy

Authors: Yunxuan Feng, Yuan Yu, Xinyang Yu, Mengyao Li, Jiaqi Lei, Yongcan Li, Zhida Liu, Shaolong Qi, Guocan Yu

Journal: Materials Today

Doi: doi.org/10.1016/j.mattod.2025.11.029

Products & Services: Protein Electrophoresis and Western

Diet-induced RKIP downregulation disrupts PC/PE-ER homeostasis to drive MASLD

Authors: Mengjie Li, Qian Ou, Qiang Qin, Jiaxi Chen, Sen Yang, Jie Zhao, Hua Meng, Xu Li, Pinglong Xu, Cunqi Ye, Xiaojian Wang

Journal: Nature Communications

PubMed ID: 41387436

Doi: 10.1038/s41467-025-65982-8

Products & Services: Protein and Antibody Isolation

A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions

Authors: Mebratu A Bitew, Tatiana C Paredes-Santos, Parag Maru, Shruthi Krishnamurthy, Yifan Wang, Lamba O Sangaré, Samuel Duley, Yoshiki Yamaryo-Botté, Cyrille Y Botté, Jeroen P J Saeij

Journal: Nature Communications

PubMed ID: 41407671

Doi: 10.1038/s41467-025-66137-5

Products & Services: Protein and Antibody Isolation