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RBM39 Contributes to MGMT Maintenance in Response to Temozolomide-Induced DNA Damage

Authors: Vahid Khalaj, Jack T Adams, Solmaz AghaAmiri, Servando Hernandez Vargas, Tyler M Bateman, Sukhen C Ghosh, Majid Momeny, Ali Azhdarinia

Journal: Cancers

PubMed ID: 41300971

Doi: 10.3390/cancers17223604

Products & Services: Protein Electrophoresis and Western

Generation of antigen-specific paired-chain antibodies using large language models

Authors: Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Gwen Jordaan, Rebecca A Gillespie, Léna Vandenabeele, Fani Pantouli, Olivia C Powers, Matthew J Vukovich, Clinton M Holt, Jeongryeol Kim, Grant Hansman, Jennifer Logue, Helen Y Chu, Sarah F Andrews, Masaru Kanekiyo, Giuseppe A Sautto, Ted M Ross, Daniel J Sheward, Jason S McLellan, Alexandra A Abu-Shmais, Ivelin S Georgiev

Journal: Cell

PubMed ID: 41192421

Doi: 10.1016/j.cell.2025.10.006.

Products & Services: Protein and Antibody Isolation

A chromosome-level genome of Astilbe chinensis unveils the evolution of a terpene biosynthetic gene cluster

Authors: Fangfang Chen, Yan Yao, Hangzhi Zhu, Jie Hu, Aohan Geng, Zhenni Xu, Xueting Fang, Weijia Cheng, Yao Zhi, Yonghong Zhang, Zixin Deng, Tiangang Liu, Li Lu

Journal: Nature Communications

PubMed ID: 41213911

Doi: 10.1038/s41467-025-64842-9.

Products & Services: Protein and Antibody Isolation

Plexin-B1 safeguards astrocyte agility and glial alignment to facilitate wound corralling and axon pathfinding in mouse spinal cord injury model

Authors: Haofei Ni, Zhilai Zhou, Molly Estill, Dalia Halawani, Chrystian Junqueira Alves, Li Shen, Ning Xie, Roland H Friedel, Hongyan Zou

Journal: Nature Communications

PubMed ID: 41253783

Doi: 10.1038/s41467-025-65095-2.

Products & Services: Protein Electrophoresis and Western

ARMH2 is a cytosolic component of CatSper crucial for sperm function

Authors: Qingqing Zhao, Shiyi Lin, Hang Kang, Yanfei Ru, Qikui Xu, Zijing Yu, Xiaofang Huang, Carlo De Rito, Giulia Sassi, Shaojie Wang, Shuya Sun, Rui Sun, Honghan Cheng, Yi Zhu, Mingxi Liu, Yongdeng Zhang, Min Jiang, Riccardo Percudani, Jean-Ju Chung, Xuhui Zeng, Zhen Yan, Jianping Wu

Journal: Nature Communications

PubMed ID: 41271765

Doi: 10.1038/s41467-025-65952-0.

Products & Services: Protein and Antibody Isolation

Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development

Authors: Hadiatullah Hadiatullah, Lianyun Lin, Zhiyan Wang, Rajamanikandan Sundarraj, Qing Wang, Xinru Lai, Nagomi Kurebayashi, Takuya Kobayashi, Toshiko Yamazawa, Yu Seby Chen, Wenlan Wang, Hongxia Zhao, Yiqing Yin, Takashi Murayama, Filip Van Petegem, Zhiguang Yuchi

Journal: Nature Communications

PubMed ID: 41253812

Doi: 10.1038/s41467-025-65096-1.

Products & Services: Protein and Antibody Isolation

Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Authors: Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan

Journal: Nature Communications

PubMed ID: 41290650

Doi: 10.1038/s41467-025-65488-3.

Products & Services: Protein and Antibody Isolation

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders

Authors: James Wellnitz; Shabbir Ahmad; Nabin Bagale; Xuemin Cheng; Jermiah Joseph; Hong Zeng; Albina Bolotokova; Aiping Dong; Shaghayegh Reza; Pegah Ghiabi; Elisa Gibson; Guiping Tu; Xianyang Li; Jian Liu; Dengfeng Dou; Jin Li; Timothy L. Foley; Anthony R. Harris; Jacquelyn L. Klug-McLeod; Jisun Lee; Zsofia Lengyel-Zhand; Justin I. Montgomery; Sylvie Sakata; Jinzhi Zhang; Hongyao Zhu; Dafydd R. Owen; Rachel J. Harding; Aled M. Edwards; Benjamin Haibe-Kains; Levon Halabelian; Alexander Tropsha; Rafael M. Cou ago

Journal: Journal of Medicinal Chemistry

PubMed ID: 41047897

Doi: 10.1021/acs.jmedchem.5c01972

Products & Services: Protein and Antibody Isolation

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Protein and Antibody Isolation