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Alternatively spliced NFKB1 transcripts enriched in Andean Aymara modulate inflammation, HIF and hemoglobin

Authors: Jihyun Song, Seonggyun Han, Ricardo Amaru, Lucie Lanikova, Teddy Quispe, Dongwook Kim, Jacob E Crawford, Soo Jin Kim, Younghee Lee, Josef T Prchal

Journal: Nature Communications

PubMed ID: 39971917

Doi: 10.1038/s41467-025-56848-0

Products & Services: Protein Electrophoresis and Western

Perturbing Organelle-Level K+/Ca2+ Homeostasis by Nanotherapeutics for Enhancing Ion-Mediated Cancer Immunotherapy

Authors: Jun-Long Liang , Qian-Xiao Huang , Qi-Wen Chen , Xiao-Kang Jin , Zi-Yi Han 1, Ping Ji , Si-Xue Cheng , Wei-Hai Chen , Xian-Zheng Zhang

Journal: Adv Mater

PubMed ID: 39955648

Doi: 10.1002/adma.202416574

Products & Services: Recombinant Proteins

Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival

Authors: Wen Wei, Xueqin Gao, Jiawei Qian, Lei Li, Chen Zhao, Li Xu, Yanfei Zhu, Zhenzhen Liu, Nengrong Liu, Xueqing Wang, Zhicong Jin, Bowen Liu, Lan Xu, Jin Dong, Suping Zhang, Jiarong Wang, Yumu Zhang, Yao Yu, Zhanjun Yan, Yanjun Yang, Jie Lu, Yixuan Fang, Na Yuan, Jianrong Wang

Journal: Journal of Clinical Investigation

PubMed ID: 39589832

Doi: 10.1172/JCI177375.

Products & Services: Protein and Antibody Isolation

Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane

Authors: Kathryn M Hastie, Zhe Li Salie, Zunlong Ke, Peter J Halfmann, Lisa Evans DeWald, Sara McArdle, Ariadna Grinyó, Edgar Davidson, Sharon L Schendel, Chitra Hariharan, Michael J Norris, Xiaoying Yu, Chakravarthy Chennareddy, Xiaoli Xiong, Megan Heinrich, Michael R Holbrook, Benjamin Doranz, Ian Crozier, Yoshihiro Kawaoka, Luis M Branco, Jens H Kuhn, John A G Briggs, Gabriella Worwa, Carl W Davis, Rafi Ahmed, Erica Ollmann Saphire

Journal: Nature Communications

PubMed ID: 39900911

Doi: 10.1038/s41467-025-56452-2

Products & Services: Protein and Antibody Isolation

Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation

Authors: Muriel Sébastien, Alexandra L Paquette, Emily N P Prowse, Adam G Hendricks, Gary J Brouhard

Journal: Nature Communications

PubMed ID: 39966472

Doi: 10.1038/s41467-025-56951-2

Products & Services: Protein Electrophoresis and Western

Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development

Authors: Feifei Yuan, Jihong Yang, Fanglin Ma, Zhe Hu, Vikas Malik, Ruge Zang, Dan Li, Xianle Shi, Xin Huang, Hongwei Zhou, Jianlong Wang

Journal: Nature Communications

PubMed ID: 39988597

Doi: 10.1038/s41467-025-57165-2

Products & Services: Protein Electrophoresis and Western

Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice

Authors: Yuxuan Chen , Xiaohong Chen , Yao Zhang , Meng Wang , Minqi Yang , Ruiji Wang , Xiaojie Yan , Shiyi Shao , Huhu Xin , Qida Hu , Wei Wei , Yuan Ping

Journal: Sci Transl Med

PubMed ID: 39813319

Doi: 10.1126/scitranslmed.adl5800

Products & Services: Recombinant Proteins

Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence

Authors: Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

Journal: Journal of nanobiotechnology

PubMed ID: 39844298

Doi: 10.1186/s12951-025-03103-9

Products & Services: Recombinant Proteins

Inhalable nanovesicles loaded with a STING agonist enhance CAR-T cell activity against solid tumors in the lung

Authors: Tianchuan Zhu, Yuchen Xiao, Zhenxing Chen, Hanxi Ding, Shoudeng Chen, Guanmin Jiang & Xi Huang

Journal: Nature Communications

PubMed ID: 39747173

Doi: 10.1038/s41467-024-55751-4

Products & Services: Protein and Antibody Reagents

Drug inhibition and substrate transport mechanisms of human VMAT2

Authors: Feiwen Wei, Huihui Liu, Wei Zhang, Jufang Wang & Yanqing Zhang