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Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

Authors: Jessica C Hargarten, Kenneth Ssebambulidde, Seher H Anjum, Malcolm J Vaughan, Jintao Xu, Anutosh Ganguly, Brittany Dulek, Francisco Otaizo-Carrasquero, Brian Song, Sijia Tao, Yoon-Dong Park, Terri L Scott, Tracey-Ann Höltermann, Raymond F Schinazi, Prashant Chittiboina, Bridgette Jeanne Billioux, Dima A Hammoud, Michal A Olszewski, Peter R Williamson

Journal: SCIENCE ADVANCES

PubMed ID: 40117367

Doi: 10.1126/sciadv.adi9885

Products & Services: Protein Electrophoresis and Western

Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator

Authors: Demeng Sun, Xiang Li, Qingning Yuan, Yuanxia Wang, Pan Shi, Huanhuan Zhang, Tao Wang, Wenjing Sun, Shenglong Ling, Yuanchun Liu, Jinglin Lai, Wenqin Xie, Wanchao Yin, Lei Liu, H. Eric Xu, Changlin Tian

Journal: Cell Res

PubMed ID: 40118988

Doi: doi.org/10.1038/s41422-025-01095-7

Products & Services: Antibody Modification and Purification Services Protein and Antibody Isolation

A Functional 3D Biomimetic Osteon Accelerates Bone Regeneration

Authors: Chenxu Zhu, Zexi Li, Xubin Qiu, Baizhen Zhao, Huan Wang, Lijie Wang, Ming Zhuang, Jinbo Liu, Fengxuan Han, Bin Li

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202500603

Products & Services: Protein and Antibody Isolation

Splenic red pulp macrophages eliminate the liver-resistant Streptococcus pneumoniae from the blood circulation of mice

Authors: Haoran An, Yijia Huang, Zhifeng Zhao, Kunpeng Li, Jingjing Meng, Xueting Huang, Xianbin Tian, Hongyu Zhou, Jiamin Wu, Qionghai Dai, Jing-Ren Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 40073120

Doi: 10.1126/sciadv.adq6399

Products & Services: Protein and Antibody Isolation

FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Authors: Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li

Journal: Advanced Science

PubMed ID: 40091484

Doi: 10.1002/advs.202408724

Products & Services: Recombinant Proteins

Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1

Authors: Qinyu Zhu, Madeleine F Yaggi, Nikolaus Jork, Henning J Jessen, Melinda M Diver

Journal: Nature Communications

PubMed ID: 40113814

Doi: 10.1038/s41467-025-58076-y

Products & Services: Protein and Antibody Isolation

GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint

Authors: Xinhui Hui, Min Xue, Yaojun Ren, Yiran Chen, Xuenan Chen, Muhammad Asad Farooq, Yuzhou Ji, Weirong Zhan, Yunhe Huang, Bingtan Du, Jie Yao, Yixin Duan, Wenzheng Jiang

Journal: Sci Adv

PubMed ID: 40043109

Doi: doi/10.1126/sciadv.adr9395

Products & Services: Protein and Antibody Isolation

Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy

Authors: Jiexin Li, Ruiqi Yang, Chen Zhang, Jonathan F Lovell, Yumiao Zhang

Journal: J Am Chem Soc

PubMed ID: 40065259

Doi: 10.1021/jacs.4c18511

Products & Services: Recombinant Proteins

Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis

Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang

Journal: JACS Au

Doi: doi/10.1021/jacsau.5c00067

Products & Services: Protein Electrophoresis and Western

Plant essential oil targets TRPV3 for skin renewal and structural mechanism of action

Authors: Yang Li, Xuteng Lu, Xufeng Cheng, Keyu Xia, Junyan Hu, Peiyu Wang, Peiyuan Pang, Bomin Gao, Demeng Sun, Zhuzhen Zhang, Dongdong Li, Zengqin Deng, Changlin Tian, Chang Xie, Jing Yao

Journal: Nature Communications

PubMed ID: 40108208

Doi: 10.1038/s41467-025-58033-9

Products & Services: Protein and Antibody Isolation