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Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov

Journal: Cell Metab

PubMed ID: 36706758

Doi: 10.1016/j.cmet.2023.01.001

Products & Services: Protein and Antibody Isolation

Protective Effects of against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles

Authors: Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng

Journal: Int J Mol Sci

PubMed ID: 36768377

Doi: 10.3390/ijms24032053

Products & Services: Protein and Antibody Isolation

Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy

Authors: Justin M Quiles, Rita H Najor, Eileen Gonzalez, Monica Jeung, Wenjing Liang, Sarah M Burbach, Erika A Zumaya, Rachel Y Diao, Mark A Lampert, Åsa B Gustafsson

Journal: Sci Signal

PubMed ID: 36719945

Doi: 10.1126/scisignal.abo4457

Products & Services: Protein and Antibody Isolation

The establishment of multiple knockout mutants of Colletotrichum orbiculare by CRISPR-Cas9 and Cre-loxP systems

Authors: Kohji Yamada, Toya Yamamoto, Kanon Uwasa, Keishi Osakabe, Yoshitaka Takano

Journal: Fungal Genet Biol

PubMed ID: 36669556

Doi: 10.1016/j.fgb.2023.103777

Products & Services: Protein and Antibody Isolation

Plant production of a virus-like particle-based vaccine candidate against porcine reproductive and respiratory syndrome

Authors: Jordan T VanderBurgt, Ondre Harper, Christopher P Garnham, Susanne E Kohalmi, Rima Menassa

Journal: Front Plant Sci

PubMed ID: 36760639

Doi: 10.3389/fpls.2023.1044675

Products & Services: Protein and Antibody Isolation

Unusual crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing in antigen presentation

Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier

Journal: Res Sq

PubMed ID: 36747752

Doi: 10.21203/rs.3.rs-2500847/v1

Products & Services: Protein and Antibody Isolation

The FACT-targeted drug CBL0137 enhances the effects of rituximab to inhibit B-cell non-Hodgkin's lymphoma tumor growth by promoting apoptosis and autophagy

Authors: Yan Lv, Yuxin Du, Kening Li, Xiao Ma, Juan Wang, Tongde Du, Yuxin Ma, Yue Teng, Weiyan Tang, Rong Ma, Jianqiu Wu, Jianzhong Wu, Jifeng Feng

Journal: Cell Commun Signal

PubMed ID: 36691066

Doi: 10.1186/s12964-022-01031-x

Products & Services: Protein and Antibody Isolation

Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

Authors: Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang

Journal: J Nanobiotechnology

PubMed ID: 36597089

Doi: 10.1186/s12951-022-01762-6

Products & Services: Protein and Antibody Isolation

Functional characterization of a novel aminoglycoside phosphotransferase, APH(9)-Ic, and its variant from

Authors: Weina Shi, Junwan Lu, Chunlin Feng, Mengdi Gao, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Xi Lin, Kewei Li, Hailin Zhang, Yunliang Hu, Guangli Wang, Qiyu Bao, Weiyan Jiang

Journal: Front Cell Infect Microbiol

PubMed ID: 36699730

Doi: 10.3389/fcimb.2022.1097561

Products & Services: Protein and Antibody Isolation

Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition

Authors: Sara Monteiro-Reis, Vera Miranda-Gonçalves, Catarina Guimarães-Teixeira, Cláudia Martins-Lima, João Lobo, Diana Montezuma, Paula C Dias, Helene Neyret-Kahn, Isabelle Bernard-Pierrot, Rui Henrique, Carmen Jerónimo

Journal: Int J Biol Sci

PubMed ID: 36594099

Doi: 10.7150/ijbs.77181

Products & Services: Protein and Antibody Isolation