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An iterative gene-editing strategy broadens eIF4E1 genetic diversity in Solanum lycopersicum and generates resistance to multiple potyvirus isolates

Authors: Kyoka Kuroiwa, Benoit Danilo, Laura Perrot, Christina Thenault, Florian Veillet, Fabien Delacote, Philippe Duchateau, Fabien Nogué, Marianne Mazier, Jean-Luc Gallois

Journal: Plant Biotechnol J

PubMed ID: 36715107

Doi: 10.1111/pbi.14003

Products & Services: Protein and Antibody Isolation

The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer

Authors: Xue Yang, Miguel I Cruz, Elizabeth V Nguyen, Cheng Huang, Ralf B Schittenhelm, Jennii Luu, Karla J Cowley, Sung-Young Shin, Lan K Nguyen, Terry C C Lim Kam Sian, Kimberley C Clark, Kaylene J Simpson, Xiuquan Ma, Roger J Daly

Journal: Oncogene

PubMed ID: 36693952

Doi: 10.1038/s41388-023-02594-w

Products & Services: Protein and Antibody Isolation

In Vitro and In Silico Studies of Kinase Inhibitor of MAPK3 Protein to Determine Leishmania martiniquensis Treatment

Authors: Thitinan Aiebchun, Natchaya Rasri, Duangnapa Kiriwan, Suradej Siripattanapipong, Kiattawee Choowongkomon

Journal: Acta Parasitol

PubMed ID: 36637694

Doi: 10.1007/s11686-023-00659-0

Products & Services: Protein and Antibody Isolation

Booster shot of inactivated SARS-CoV-2 vaccine induces potent immune responses in people living with HIV

Authors: Haoting Zhan, Huixia Gao, Yongmei Liu, Xihong Zhang, Haolong Li, Xiaomeng Li, Lijing Wang, Chen Li, Beilei Li, Yuling Wang, Erhei Dai, Yongzhe Li

Journal: J Med Virol

PubMed ID: 36571267

Doi: 10.1002/jmv.28428

Products & Services: Protein and Antibody Isolation

Structural Basis for Self-Discrimination by Neoantigen-Specific TCRs

Authors: John P Finnigan, Jenna H Newman, Yury Patskovsky, Larysa Patskovska, Andrew S Ishizuka, Geoffrey M Lynn, Robert A Seder, Michelle Krogsgaard, Nina Bhardwaj

Journal: Res Sq

PubMed ID: 36778273

Doi: 10.21203/rs.3.rs-2531184/v1

Products & Services: Protein and Antibody Isolation

Protective Effects of against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles

Authors: Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng

Journal: Int J Mol Sci

PubMed ID: 36768377

Doi: 10.3390/ijms24032053

Products & Services: Protein and Antibody Isolation

Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov