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Optimization of an alum-anchored clinical HIV vaccine candidate

Authors: Kristen A Rodrigues, Christopher A Cottrell, Jon M Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y H Chang, Parisa Yousefpour, Mariane B Melo, William R Schief, Darrell J Irvine

Journal: npj Vaccines

PubMed ID: 37573422

Doi: 10.1038/s41541-023-00711-0

Products & Services: Recombinant Proteins

High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase

Authors: Lu Yang, Tristan Wagner, Ariel Mechaly, Alexandra Boyko, Eduardo M Bruch, Daniela Megrian, Francesca Gubellini, Pedro M Alzari, Marco Bellinzoni

Journal: Nat Commun

PubMed ID: 37563123

Doi: 10.1038/s41467-023-40253-6

Products & Services: Protein and Antibody Isolation

Directed evolution rice genes with randomly multiplexed sgRNAs assembly of base editors

Authors: Ao Zhang, Tiaofeng Shan, Yan Sun, Zhipeng Chen, Jianjian Hu, Zhichao Hu, Ziheng Ming, Zhitao Zhu, Xue Li, Jun He, Shijia Liu, Ling Jiang, Xiaoou Dong, Yufeng Wu, Yanpeng Wang, Yuqiang Liu, Chao Li, Jianmin Wan

Journal: Plant Biotechnol J

PubMed ID: 37571976

Doi: 10.1111/pbi.14156

Products & Services: Protein and Antibody Isolation

Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting

Authors: Stefania Torino, Mugdha Dhurandhar, Annelore Stroobants, Raf Claessens, Rouslan G Efremov

Journal: Nat Methods

PubMed ID: 37592181

Doi: 10.1038/s41592-023-01967-z

Products & Services: Protein and Antibody Isolation

Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells

Authors: Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michael J McCluskie, Yves Durocher

Journal: Commun Med (Lond)

PubMed ID: 37612423

Doi: 10.1038/s43856-023-00340-7

Products & Services: Protein and Antibody Isolation

A non-toxic recombinant Clostridium septicum α toxin induces protective immunity in mice and rabbits

Authors: Jige Du, Irene Meki, Qianlin Li, Ying Liu, Zhen Zhu, Chenfan Pan, Yingju Xia, Lizhi Fu, Liu Yang, Suhui Zhang, Chunsheng Yin, Yufeng Luo, Tuanjie Wang, Bo Liu, Xiaoyun Chen

Journal: Toxicon

PubMed ID: 37543293

Doi: 10.1016/j.toxicon.2023.107234

Products & Services: Protein and Antibody Isolation

Directed evolution of TetR for constructing sensitive and broad-spectrum tetracycline antibiotics whole-cell biosensor

Authors: Shunlan Li, Dongdong Chen, Ziqing Liu, Shipin Tao, Tianyi Zhang, Yiwen Chen, Lingzhi Bao, Jie Ma, Yuee Huang, Shengmin Xu, Lijun Wu, Shaopeng Chen

Journal: J Hazard Mater

PubMed ID: 37633019

Doi: 10.1016/j.jhazmat.2023.132311

Products & Services: Protein and Antibody Isolation

Immunogenicity, safety and reactogenicity of heterologous (third dose) booster vaccination with a full or fractional dose of two different COVID-19 vaccines: A phase 4, single-blind, randomized controlled trial in adults

Authors: Sue Ann Costa Clemens, Natalie Marchevsky, Sarah Kelly, Sally Felle, Ahmed Eldawi, Rupetha Rajasingam, Rawan Mahmud, Teresa Lambe, Merryn Voysey, Isabela Gonzalez, Eveline Pipolo Milan, Maria Cleonice Justino, Sagida Bibi, Parvinder Aley, Ralf Clemens, Andrew J Pollard

Journal: Hum Vaccin Immunother

PubMed ID: 37438960

Doi: 10.1080/21645515.2023.2233400

Products & Services: Protein and Antibody Isolation

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1

Authors: Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey F Taylor, Zu-Wen Sun, Ryan J Ezell, Anup Vaidya, Matthew J Meiners, Marcus A Cheek, William J Rice, Vladimir Svetlov, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache

Journal: Sci Adv

PubMed ID: 37556531

Doi: 10.1126/sciadv.adg9832

Products & Services: Protein and Antibody Isolation

Photoaffinity labelling displacement assay using multiple recombinant protein domains

Authors: David J Fallon, Alex Phillipou, Christopher J Schofield, David House, Nicholas C O Tomkinson, Jacob T Bush

Journal: Biochem J

PubMed ID: 37401534

Doi: 10.1042/BCJ20230129

Products & Services: Protein and Antibody Isolation