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Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern

Authors: Tyler M Renner, Bassel Akache, Matthew Stuible, Nazanin Rohani, Yuneivy Cepero-Donates, Lise Deschatelets, Renu Dudani, Blair A Harrison, Jason Baardsnes, Izel Koyuturk, Jennifer J Hill, Usha D Hemraz, Sophie Régnier, Anne E G Lenferink, Yves Durocher, Michael J McCluskie

Journal: Frontiers in Immunology

PubMed ID: 37122746

Doi: 10.3389/fimmu.2023.1182556

Products & Services: Recombinant Proteins Gene Synthesis

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases

Authors: Iris D Zelnik, Beatriz Mestre, Jonathan J Weinstein, Tamir Dingjan, Stav Izrailov, Shifra Ben-Dor, Sarel J Fleishman, Anthony H Futerman

Journal: Nat Commun

PubMed ID: 37087500

Doi: 10.1038/s41467-023-38047-x

Products & Services: Proteins, Expression, Isolation and Analysis

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb based on CRISPR/Cas12a empowered electrochemical biosensor

Authors: Yuanyuan Yue, Songtao Wang, Qiang Jin, Nan An, Lina Wu, He Huang

Journal: Anal Chim Acta

PubMed ID: 37225346

Doi: 10.1016/j.aca.2023.341241

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria

Authors: Sukyeong Lee, Sang Bum Lee, Nuri Sung, Wendy W Xu, Changsoo Chang, Hyun-Eui Kim, Andre Catic, Francis T F Tsai

Journal: Nat Commun

PubMed ID: 37041140

Doi: 10.1038/s41467-023-37657-9

Products & Services: Proteins, Expression, Isolation and Analysis

Interaction of LARP4 to filamin A mechanosensing domain regulates cell migrations

Authors: Zhenfeng Mao, Fumihiko Nakamura

Journal: Front Cell Dev Biol

PubMed ID: 37169020

Doi: 10.3389/fcell.2023.1152109

Products & Services: Proteins, Expression, Isolation and Analysis

Organization, genomic targeting, and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis

Authors: Wei Fu, Yaoguang Yu, Jie Shu , Zewang Yu, Yixiong Zhong, Tao Zhu, Zhihao Zhang, Zhenwei Liang, Yuhai Cui, Chen Chen , Chenlong Li

Journal: Plant Cell .

PubMed ID: 37062961

Doi: 10.1093/plcell/koad111

Products & Services: Proteins, Expression, Isolation and Analysis

SLFN5-mediated chromatin dynamics sculpt higherorder DNA repair topology

Authors: Jinzhou Huang, Chenming Wu, Jake A Kloeber, Huanyao Gao, Ming Gao, Qian Zhu, Yiming Chang, Fei Zhao, Guijie Guo, Kuntian Luo, Haiming Dai, Sijia Liu, Qiru Huang, Wootae Kim, Qin Zhou, Shouhai Zhu, Zheming Wu, Xinyi Tu, Ping Yin, Min Deng, Liewei Wang, Jian Yuan, Zhenkun Lou

Journal: molecular cell

PubMed ID: 36854302

Doi: 10.1016/j.molcel.2023.02.004

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Multifunctional activity-based chemical probes for sirtuins

Authors: Chiranjeev Sharma, Dickson Donu, Alyson M Curry, Elizabeth Barton, Yana Cen

Journal: RSC Adv

PubMed ID: 37063743

Doi: 10.1039/d3ra02133e

Products & Services: Proteins, Expression, Isolation and Analysis

Enhanced Degradation of Mutant -Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection

Authors: Allison S Vanecek, Jelena Mojsilovic-Petrovic, Robert G Kalb, Jetze J Tepe

Journal: ACS Chem Neurosci

PubMed ID: 37015082

Doi: 10.1021/acschemneuro.2c00732

Products & Services: Recombinant Proteins

Lactucin Synthase Inactivation Boosts the Accumulation of Anti-inflammatory 8-Deoxylactucin and Its Derivatives in Chicory ( L)

Authors: Katarina Cankar, Johanna Christina Hakkert, Robert Sevenier, Christina Papastolopoulou, Bert Schipper, João P Baixinho, Naiara Fernández, Melanie S Matos, Ana Teresa Serra, Claudia Nunes Santos, Khabat Vahabi, Alain Tissier, Paul Bundock, Dirk Bosch

Journal: J Agric Food Chem

PubMed ID: 37036799

Doi: 10.1021/acs.jafc.2c08959

Products & Services: Proteins, Expression, Isolation and Analysis