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Design and Semisynthesis of Ubiquitin Extension Probes for Structural Analysis of Cullin1-Mediated Substrate Polyubiquitination

Authors: Chuntong Li, Fangyu Zhao, Chong Zuo, Liying Zhang, Yangwode Jing, Xu Li, Guo-Chao Chu, Luyu Shi, Yingyue Zhang, Han Wang, Shuzhe Sun, Maoshen Sun, Huasong Ai, Lu-Jun Liang, Jinghong Li

Journal: Journal of the American Chemical Society

PubMed ID: 40561458

Doi: 10.1021/jacs.5c06399

Products & Services: Gene Synthesis Codon Optimization

Improving diffusion-based protein backbone generation with global-geometry-aware latent encoding

Authors: Yuyang Zhang, Yuhang Liu, Zinnia Ma, Min Li, Chunfu Xu & Haipeng Gong

Journal: Nature Machine Intelligence

Doi: doi.org/10.1038/s42256-025-01059-x

Products & Services: Gene Synthesis

Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses

Authors: Kong Yen Liew, Yaju Wang, Sneha Sree Mullapudi, Dinah Binte Aziz, Wenjie Fan, Min Luo, Paul Anantharajah Tambyah, Yee-Joo Tan

Journal: Viruses

PubMed ID: 40733504

Doi: 10.3390/v17070886

Products & Services: Gene Synthesis Codon Optimization PCR Cloning and Subcloning

Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain

Authors: Guillaume Mas , Sebastian Hiller

Journal: Nature Communications

PubMed ID: 40449998

Doi: 10.1038/s41467-025-60343-x

Products & Services: Gene Synthesis

RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

Authors: Akihito Sakoguchi, Samuel G Chamberlain, Alexander M Mørch, Marcus Widdess, Thomas E Harrison, Michael L Dustin, Hisashi Arase, Matthew K Higgins, Shiroh Iwanaga

Journal: Nature

PubMed ID: 40500441

Doi: 10.1038/s41586-025-09091-y

Products & Services: Gene Synthesis

Identification of a gene conferring broad-spectrum orthotospovirus resistance in Solanaceae

Authors: Yong Liu, Jie Wang, Chongkun Zuo, Weishu Fan, Cheng Yuan, Jianmin Zeng, Haiqin Yu, Zhijun Tong, Xueyi Sui, Yi Xu, Min Zhu, Xiaorong Tao, Jiongjiong Chen, Hanhui Kuang, Polina Yu Novikova, Changjun Huang

Journal: SCIENCE ADVANCES

PubMed ID: 40532009

Doi: 10.1126/sciadv.adw4333

Products & Services: Gene Synthesis

A New Vaccine Candidate Expressing JUNV GP1–GP2 Against Argentine Hemorrhagic Fever Based on Baculovirus Surface Display

Authors: Carla Tomatis, Mara C A M Aguiar, Nancy Charo, Silvia Aquila, Pablo D Thomas, Paula N Arrías, Matías L Pidre, Víctor Romanowski, Laura Riera, Julia Brignone, Andrea Maiza, Eugenio Antonio Carrera Silva, María Florencia Ferrer, Ricardo Martín Gómez

Journal: Current microbiology

PubMed ID: 40514553

Doi: 10.1007/s00284-025-04320-z

Products & Services: Gene Synthesis

Deciphering the role of accessory proteins in Arabidopsis chloroplast editosomes via interaction with a synthetic PPR-PLS factor in E. coli

Authors: Jose M Lombana , Maureen R Hanson , Stéphane Bentolila

Journal: Nucleic Acids Research

PubMed ID: 40498070

Doi: 10.1093/nar/gkaf483

Products & Services: Gene Synthesis

Mechanism of DNA degradation by CBASS Cap5 endonuclease immune effector

Authors: Olga Rechkoblit, Daniela Sciaky, Mi Ni, Yangmei Li, Jithesh Kottur, Gang Fang, Aneel K Aggarwal

Journal: Nature Communications

PubMed ID: 40473611

Doi: 10.1038/s41467-025-60484-z

Products & Services: Gene Synthesis

Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish

Authors: Sema Elif Eski, Jiarui Mi, Macarena Pozo-Morales, Gabriel Garnik Hovhannisyan, Camille Perazzolo, Rita Manco, Imane Ez-Zammoury, Dev Barbhaya, Anne Lefort, Frédérick Libert, Federico Marini, Esteban N Gurzov, Olov Andersson, Sumeet Pal Singh

Journal: nature COMMUNICATION

PubMed ID: 40480975

Doi: 10.1038/s41467-025-60334-y

Products & Services: Gene Synthesis