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Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2

Authors: Qian Wang, Yicheng Guo, Ryan G Casner, Jian Yu, Manoj S Nair, Jerren Ho, Eswar R Reddem, Ian A Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D Ho

Journal: Nature Communications

PubMed ID: 40615407

Doi: 10.1038/s41467-025-61472-z

Products & Services: Gene Synthesis

Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses

Authors: Tobias Plowman, Tom Hofland, Callum Hall, Rachael Thompson, Judith Pape, Kevin W Ng, Laura Doglio, George Kassiotis

Journal: SCIENCE ADVANCES

PubMed ID: 40614216

Doi: 10.1126/sciimmunol.adr1105

Products & Services: Gene Synthesis

Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

Authors: De Xing, Tao Bai, Ozlem Neyisci, Seyedeh Zahra Paylakhi, Alexander J Duval, Yasemin Tekin, Mazhar Adli

Journal: Nature Communications

PubMed ID: 40681502

Doi: 10.1038/s41467-025-61848-1

Products & Services: Gene Synthesis

Non-antibiotics disrupt colonization resistance against enteropathogens

Authors: Anne Grießhammer, Jacobo de la Cuesta-Zuluaga, Patrick Müller, Cordula Gekeler, Jan Homolak, Hsuan Chang, Katharina Schmitt, Chiara Planker, Verena Schmidtchen, Suchira Gallage, Erwin Bohn, Taylor H Nguyen, Jenny Hetzer, Mathias Heikenwälder, Kerwyn Casey Huang, Taiyeb Zahir, Lisa Maier

Journal: Nature

PubMed ID: 40670795

Doi: 10.1038/s41586-025-09217-2

Products & Services: Gene Synthesis

The mitotic chromosome periphery modulates chromosome mechanics

Authors: Tania Mendonca, Roman Urban, Kellie Lucken, George Coney, Neil M Kad, Manlio Tassieri, Amanda J Wright, Daniel G Booth

Journal: Nature Communications

PubMed ID: 40640170

Doi: 10.1038/s41467-025-61755-5

Products & Services: Gene Synthesis

Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans

Authors: Lena Peters, Moritz Drechsler, Michael A Herrera, Jing Liu, Barbara Pees, Johanna Jarstorff, Anna Czerwinski, Francesca Lubbock, Georgia Angelidou, Liesa Salzer, Karlis Arturs Moors, Nicole Paczia, Yi-Ming Shi, Hinrich Schulenburg, Christoph Kaleta, Michael Witting, Manuel Liebeke, Dominic J Campopiano, Helge B Bode, Katja Dierking

Journal: Nature Communications

PubMed ID: 40461452

Doi: 10.1038/s41467-025-60234-1

Products & Services: Gene Synthesis

KIF2C condensation concentrates PLK1 and phosphorylated BRCA2 on kinetochore microtubules in mitosis

Authors: Anastasiia Skobelkina, Manon Julien, Sylvain Jeannin, Simona Miron, Tom Egger, Rady Chaaban, Guillaume Bouvignies, Emile Alghoul, Rania Ghouil, Claire Friel, Didier Busso, Juan C Cañas, François-Xavier Theillet, Romain Le Bars, Aura Carreira, Angelos Constantinou, Jihane Basbous, Sophie Zinn-Justin

Journal: Nucleic Acids Research

PubMed ID: 40498077

Doi: 10.1093/nar/gkaf476

Products & Services: Gene Synthesis

Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2

Authors: Zhen Wang , Xiaofan Zhang ， Can Zhou , Xiaofeng Cao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 40478869

Doi: 10.1073/pnas.2502155122

Products & Services: Gene Synthesis

Collective Biosynthesis of Plant Spirooxindole Alkaloids through Enzyme Discovery and Engineering

Authors: Danni Chu, Hongkui Wang, Zhiwen Nie, Kang-Li Li, Jiaqing Cao, Meijing Yang, Qin Yin, Yang Gu, Yindi Jiang

Journal: Journal of the American Chemical Society

PubMed ID: 40504680

Doi: 10.1021/jacs.5c02990

Products & Services: Gene Synthesis

Electrochemical sensor toolkit for simultaneous glutamate detection at edge of cleft and peri-soma

Authors: Jie Liu, Yuandong Liu, Dongmin Yin, Yang Tian

Journal: Cell chemical biology

PubMed ID: 40466640

Doi: 10.1016/j.chembiol.2025.05.002

Products & Services: Gene Synthesis