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Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage

Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin

Journal: Mol Ther Nucleic Acids

PubMed ID: 40125272

Doi: doi.org/10.1016/j.omtn.2025.102485

Products & Services: Gene Synthesis

Controllable intein splicing and N-terminal cleavage at mesophilic temperatures

Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon

Journal: Front Bioeng Biotechnol

PubMed ID: 39991137

Doi: 10.3389/fbioe.2025.1543573

Products & Services: Gene Synthesis Mutagenesis Services

ABC transporter activity is affected by the size of lipid nanodiscs

Authors: Annabella Nouel Barreto, Luis G Cuello, Maria E Zoghbi

Journal: FEBS Letters

PubMed ID: 39748569

Doi: 10.1002/1873-3468.15096

Products & Services: Gene Synthesis Custom Vector Construction

Massively parallel variant-to-function mapping determines functional regulatory variants of non-small cell lung cancer

Authors: Congcong Chen, Yang Li, Yayun Gu, Qiqi Zhai, Songwei Guo, Jun Xiang, Yuan Xie, Mingxing An, Chenmeijie Li, Na Qin, Yanan Shi, Liu Yang, Jun Zhou, Xianfeng Xu, Ziye Xu, Kai Wang, Meng Zhu, Yue Jiang, Yuanlin He, Jing Xu, Rong Yin, Liang Chen, Lin Xu, Juncheng Dai, Guangfu Jin, Zhibin Hu, Cheng Wang, Hongxia Ma, Hongbing Shen

Journal: Nature Communications

PubMed ID: 39910069

Doi: 10.1038/s41467-025-56725-w

Products & Services: Gene Synthesis

Expression, purification and characterization of a novel triple fusion protein developed for the immunotherapy of survivin positive cancers

Authors: Ambreen Rashid, Mohammad Azad, Anuja Krishnan, Jagdish C Gupta, G P Talwar

Journal: Protein Expression and Purification

PubMed ID: 39396748

Doi: 10.1016/j.pep.2024.106614

Products & Services: Gene Synthesis

Antibody prophylaxis may mask subclinical SIV infections in macaques

Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.

Journal: Nature

PubMed ID: 39910294

Doi: 10.1038/s41586-024-08500-y

Products & Services: Gene Synthesis

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Humanized Recombinant Immunotoxin Targeting hCG Demonstrates Therapeutic Potential for Advanced Stage Difficult to Treat Cancers

Authors: Kirti Nain, Kritika Sonar, Sibasis Sahoo, Jagdish C Gupta, Sonam Grover, Arockiasamy Arulandu, G P Talwar

Journal: Journal of durg targeting

PubMed ID: 39394941

Doi: 10.1080/1061186X.2024.2416247

Products & Services: Gene Synthesis

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

Products & Services: Gene Synthesis