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C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening

Authors: Guiyou Tian, Lirong Huang, Zhaopeng Xu, Chen Lu, Wei Yuan, Yulin Wu, Zhipeng Liao, Jia Gao, Qiang Luo, Bo Cheng, Xinjun Liao, Huiqiang Lu

Journal: SCIENCE ADVANCES

PubMed ID: 40344050

Doi: 10.1126/sciadv.adv2032

Products & Services: Gene Synthesis

Auxin-salicylic acid seesaw regulates the age-dependent balance between plant growth and herbivore defense

Authors: Wen-Hao Han, Feng-Bin Zhang, Shun-Xia Ji, Kai-Lu Liang, Jun-Xia Wang, Xiao-Ping Fan, Shu-Sheng Liu, Xiao-Wei Wang

Journal: SCIENCE ADVANCES

PubMed ID: 40344064

Doi: 10.1126/sciadv.adu5141

Products & Services: Gene Synthesis

Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP

Authors: Justin M Waldern, Colin Taylor, Catherine A Giannetti, Patrick S Irving, Scott R Allen, Mingyi Zhu, Rolf Backofen, Dave Mathews, Kevin M Weeks, Alain Laederach

Journal: Nucleic Acids Research

PubMed ID: 39713457

Doi: 10.1101/2024.12.13.628372

Products & Services: Gene Synthesis

Fe(III)−H2O2 as an Alternative Oxidant for Catalytic Sulfoxidation in Cytochrome P450 Enzymes: Combined Theoretical and Experimental Evidence

Authors: Musen Li, Langxing Liao, Zhihui Jiang, Zongyu Bao, Shengbiao Ji, Binju Wang

Journal: ACS catalysis

Doi: doi.org/10.1021/acscatal.5c01673

Products & Services: Gene Synthesis Codon Optimization

Influence of expression and purification protocols on G biochemical activity: kinetics of plant and mammalian G protein cycles

Authors: Timothy E. Gookin; David Chakravorty; Sarah M. Assmann

Journal: Frontiers in molecular biosciences

PubMed ID: 40260404

Doi: 10.3389/fmolb.2025.1513660

Products & Services: Gene Synthesis

HR eye & MMR eye: one-day assessment of DNA repair-defective tumors eligible for targeted therapy

Authors: Shinta Saito, Shingo Kato, Usaki Arai, Atsuki En, Jun Tsunezumi, Taichi Mizushima, Kensuke Tateishi, Noritaka Adachi

Journal: Nature Communications

PubMed ID: 40355434

Doi: 10.1038/s41467-025-59462-2

Products & Services: Gene Synthesis

A FAN1 point mutation associated with accelerated Huntington's disease progression alters its PCNA-mediated assembly on DNA

Authors: Jonas Aretz, Gayathri Jeyasankar, Anna Salerno-Kochan, Maren Thomsen, Gabriel Thieulin-Pardo, Tasir Haque, Edith Monteagudo, Dan Felsenfeld, Michael Finley, Thomas F Vogt, Julien Boudet, Brinda C Prasad

Journal: Nature Communications

PubMed ID: 40368883

Doi: 10.1038/s41467-025-59324-x

Products & Services: Gene Synthesis

Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces

Authors: Xiaowei Li, Yanyan Wang, Xin Chen, Leon Eisentraut, Chunjun Zhan, Jens Nielsen, Yun Chen

Journal: Nature Communications

PubMed ID: 40379631

Doi: 10.1038/s41467-025-59966-x

Products & Services: Gene Synthesis

Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca2+ dependent allosteric binding site

Authors: Leslie A Dakin, Li Xing, Justin Hall, Weidong Ding, Felix F Vajdos, Jeffrey W Pelker, Simeon Ramsey, Paul Balbo, Parag V Sahasrabudhe, Mary Ellen Banker, Won Young Choi, Stephen W Wright, Jeanne S Chang, John M Curto, Jennifer E Davoren, Susan E Drozda, Kimberly F Fennell, Kentaro Futatsugi, Steve Kortum, Katherine L Lee, Shenping Liu, Frank Lovering, Jennifer A Nicki, John I Trujillo, Fabien Vincent, Mark E Schnute

Journal: Nature Communications

PubMed ID: 40379660

Doi: 10.1038/s41467-025-59919-4

Products & Services: Gene Synthesis

Interaction networks of SIM-binding groove mutants reveal alternate modes of SUMO binding and profound impact on SUMO conjugation

Authors: Laura A Claessens, Matty Verlaan-de Vries, Nienke Broekman, Martijn S Luijsterburg, Alfred C O Vertegaal

Journal: SCIENCE ADVANCES

PubMed ID: 40367183

Doi: 10.1126/sciadv.adp2643

Products & Services: Gene Synthesis