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Chikungunya Virus and Its Envelope Protein E2 Induce Hyperalgesia in Mice: Inhibition by Anti-E2 Monoclonal Antibodies and by Targeting TRPV1

Authors: Carina Z Segato-Vendrameto, Camila Zanluca, Amanda Z Zucoloto, Tiago H Zaninelli, Mariana M Bertozzi, Telma Saraiva-Santos, Camila R Ferraz, Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Marília F Manchope, Amanda M Dionisio, Felipe A Pinho-Ribeiro, Sergio M Borghi, Ana Luiza Pamplona Mosimann, Rubia Casagrande, Juliano Bordignon, Victor Fattori, Claudia N Duarte Dos Santos, Waldiceu A Verri

Journal: Cells

PubMed ID: 36831223

Doi: 10.3390/cells12040556

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Expression and kinetic characterization of PYCR3 Kaylen

Authors: Kaylen R Meeks , John J Tanner

Journal: Arch Biochem Biophys

PubMed ID: 36414121

Doi: 10.1016/j.abb.2022.109468

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Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex

Authors: Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Ballabio, James H Hurley

Journal: Nature

PubMed ID: 36697823

Doi: 10.1038/s41586-022-05652-7

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mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Authors: Clifford T H Hayashi , Yi Cao , Leor C Clark , Abhai K Tripathi , Fidel Zavala , Garima Dwivedi , James Knox , Mohamad-Gabriel Alameh , Paulo J C Lin , Ying K Tam , Drew Weissman , Nirbhay Kumar

Journal: NPJ Vaccines

PubMed ID: 36456563

Doi: 10.1038/s41541-022-00577-8

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Efficient Production of Epoxy-Norbornane from Norbornene by an Engineered P450 Peroxygenase

Authors: Yu Yan, Chenni Zheng, Wei Song, Jing Wu, Liang Guo, Cong Gao, Jia Liu, Xiulai Chen, Meng Zhu, Liming Liu

Journal: Chembiochem

PubMed ID: 36354378

Doi: 10.1002/cbic.202200529

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Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

Authors: Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara

Journal: Transl Res

PubMed ID: 36347491

Doi: 10.1016/j.trsl.2022.11.003

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Recombinant Vaccinia Virus Expressing Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against Infection in Mice

Authors: Min-Ju Kim, Ki-Back Chu, Su-Hwa Lee, Hae-Ji Kang, Keon-Woong Yoon, Md Atique Ahmed, Fu-Shi Quan

Journal: Trop Med Infect Dis

PubMed ID: 36355892

Doi: 10.3390/tropicalmed7110350

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TMBIM5 is the Ca /H antiporter of mammalian mitochondria

Authors: Shane Austin, Ronald Mekis, Sami E M Mohammed, Mariafrancesca Scalise, Wen-An Wang, Michele Galluccio, Christina Pfeiffer, Tamara Borovec, Katja Parapatics, Dijana Vitko, Nora Dinhopl, Nicolas Demaurex, Keiryn L Bennett, Cesare Indiveri, Karin Nowikovsky

Journal: EMBO Rep

PubMed ID: 36321428

Doi: 10.15252/embr.202254978

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Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling

Authors: Bo Yu, Shiyu Luo, Yuhan Ding, Zijie Gong, Ting Nie

Journal: AMB Express

PubMed ID: 36370155

Doi: 10.1186/s13568-022-01489-5

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Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease

Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu

Journal: Angew Chem Int Ed Engl

PubMed ID: 36308706

Doi: 10.1002/anie.202212378

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