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Amylin, human, amide

Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.
￥1300
RP11278

产品概述
Synonyms Diabetes-Associated Peptide (DAP), amide, humanInsulinoma or islet amyloid polypeptide (IAPP)
Description Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. Amylin blocks the activation of glycogen synthase by insulin.
Cas No 122384-88-7
Sequence
{LYS}{CYS}{ASN}{THR}{ALA}{THR}{CYS}{ALA}{THR}{GLN}{ARG}{LEU}
{ALA}{ASN}{PHE}{LEU}{VAL}{HIS}{SER}{SER}{ASN}{ASN}{PHE}{GLY}
{ALA}{ILE}{LEU}{SER}{SER}{THR}{ASN}{VAL}{GLY}{SER}{ASN}{THR}
{TYR}
Sequence Shortening KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Molecular Formula C165H261N51O55S2
C Terminal Amidation
Disulfide Bridge 2-7
Molecular Weight 3903.28
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产品属性
Purity > 95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store at -20°C. Keep container tightly closed. Store in a cool dry place.
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