protein A, G和L不同物种IgG及其亚基的结合特性
物种 |
抗体类型 |
protein A |
protein G |
protein L |
Human |
total IgG |
+++ |
+++ |
+++ |
IgG1 |
+++ |
+++ |
+++ |
IgG2 |
+++ |
+++ |
+++ |
IgG3 |
+ |
+++ |
+++ |
IgG4 |
+++ |
+++ |
+++ |
IgM |
+ |
- |
+++ |
IgD |
- |
- |
+++ |
IgA |
+ |
- |
+++ |
Fab |
+ |
+ |
+++ |
ScFv |
+ |
- |
+++ |
Mouse |
total IgG |
+++ |
+++ |
+++ |
IgM |
- |
- |
+++ |
IgG1 |
+ |
++ |
+++ |
IgG2a |
+++ |
+++ |
+++ |
IgG2b |
+++ |
+++ |
+++ |
IgG3 |
+++ |
+++ |
+++ |
Rat |
total IgG |
+ |
++ |
+++ |
IgG1 |
+ |
++ |
+++ |
IgG2a |
- |
+++ |
+++ |
IgG2b |
- |
+ |
+++ |
IgG2c |
+++ |
+++ |
+++ |
Goat |
total IgG |
+ |
+++ |
- |
IgG1 |
+ |
+++ |
- |
IgG2 |
+++ |
+++ |
- |
Sheep |
total IgG |
+ |
+++ |
- |
IgG1 |
+ |
+++ |
- |
IgG2 |
+++ |
+++ |
- |
Rabbit |
total IgG |
+++ |
+++ |
+ |
Horse |
total IgG |
+ |
+++ |
? |
IgG(ab) |
+ |
- |
? |
IgG(c) |
+ |
- |
? |
IgG(T) |
- |
+++ |
? |
Bovine |
total IgG |
+ |
+++ |
- |
IgG1 |
+ |
+++ |
- |
IgG2 |
+++ |
+++ |
- |
Guinea Pig |
total IgG |
+++ |
- |
? |
Pig |
total IgG |
+++ |
+ |
+++ |
Dog |
total IgG |
+++ |
- |
? |
Cat |
total IgG |
+++ |
- |
? |
Chicken |
total IgY |
- |
- |
- |