GenScript - Make Research Easy - The leader in molecular cloning and gene synthesis, peptide synthesis,protein and antibody engineering.

Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies

Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao

Journal: Nat Commun

PubMed ID: 39528513

Doi: 10.1038/s41467-024-54150-z

Products & Services: Recombinant Proteins Gene Synthesis

Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma

Authors: Dongpeng Jiang, Haiwen Huang, Huimin Qin, Koukou Tang, Xiangru Shi, Tingting Zhu, Yuqing Gao, Ying Zhang, Xiaopeng Tian, Jianhong Fu, Weiwei Qu, Weilan Cai, Yang Xu, Depei Wu, Jianhong Chu

Journal: Nat Commun

PubMed ID: 37339964

Doi: 10.1038/s41467-023-39395-4

Products & Services: Recombinant Proteins

Neutralizing antibody responses against SARS-CoV-2 in patients with plasma cell disorders who are on active treatment after two doses of mRNA vaccination

Authors: Al-Ola Abdallah, Zahra Mahmoudjafari, Tahani Atieh, Nausheen Ahmed, Wei Cui, Leyla Shune, Meera Mohan, Joseph McGuirk, Cassie Remker, Margaret Foss, Ellie Karloff, Heather Fitch, Shebli Atrash

Journal: Eur J Haematol

PubMed ID: 35810359

Doi: 10.1111/ejh.13826

A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma

Authors: Mengshang Xiong, Ruoqi Liu, Xiaomin Lei, Dongmei Fan, Fangzhen Lin, Wei Hao, Xiangfei Yuan, Yuanyuan Yang, Xiaolong Zhang, Zhou Ye, Yang Lu, Yanjun Zhang, Jianxiang Wang, Dongsheng Xiong

Journal: J Immunother

PubMed ID: 34711791

Doi: 10.1097/CJI.0000000000000401

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma

Authors: Mengshang Xiong, Ruoqi Liu, Xiaomin Lei, Dongmei Fan, Fangzhen Lin, Wei Hao, Xiangfei Yuan, Yuanyuan Yang, Xiaolong Zhang, Zhou Ye, Yang Lu, Yanjun Zhang, Jianxiang Wang, Dongsheng Xiong

Journal: J Immunother

PubMed ID: 34711791

Doi: 10.1097/CJI.0000000000000401

Products & Services: Proteins, Expression, Isolation and Analysis

Full-length recombinant antibodies from : production, characterization, effector function (Fc) engineering, and clinical evaluation

Authors:

Journal: MAbs

PubMed ID: 36018829

Doi: 10.1080/19420862.2022.2111748

Products & Services: Gene Synthesis

A BCMAxCD3 bispecific T cell-engaging antibody demonstrates robust antitumor efficacy similar to that of anti-BCMA CAR T cells

Authors: David J DiLillo, Kara Olson, Katja Mohrs, Thomas Craig Meagher, Kevin Bray, Olga Sineshchekova, Thomas Startz, Jessica Kuhnert, Marc W Retter, Stephen Godin, Prachi Sharma, Frank Delfino, John Lin, Eric Smith, Gavin Thurston, Jessica R Kirshner

Journal: Blood Adv

PubMed ID: 33651100

Doi: 10.1182/bloodadvances.2020002736

Products & Services: Custom Vector Construction

BCMA-targeted immunotherapy for multiple myeloma

Authors: Yu B, Jiang T, Liu D

Journal: Journal of hematology & oncology

PubMed ID: 32943087

Doi: 10.1186/s13045-020-00962-7

Products & Services: Catalog Antibody

Adjuvant ruxolitinib therapy relieves steroid-refractory cytokine-release syndrome without impairing chimeric antigen receptor-modified T-cell function

Authors: Shuning Wei, Runxia Gu, Yingxi Xu, Xiaoyu Liu, Yanyan Xing, Xiaoyuan Gong, Chunlin Zhou, Bingcheng Liu, Guangji Zhang, Kaiqi Liu, Hui Wei, Yingchang Mi, Min Wang, Ying Wang, Jianxiang Wang

Journal: Immunotherapy

PubMed ID: 32777959

Doi: 10.2217/imt-2020-0116

Products & Services: GenParts™ DNA Fragments

BCMA-targeting Bispecific Antibody That Simultaneously Stimulates NKG2D-enhanced Efficacy Against Multiple Myeloma

Authors: Yang Wang, Hui Li, Wei Xu, Mingzhu Pan, Chun Qiao, Jialing Cai, Jingjing Xu, Min Wang, Juan Zhang

Journal: J Immunother

PubMed ID: 32349046

Doi: 10.1097/CJI.0000000000000320

Products & Services: Gene Synthesis

全部

资源中心

技术支持

关于我们